POLR2I Blocking Peptide – Cat# MBS9626040

POLR2I Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: POLR2I Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9626040
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9626040

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POLR2I, Blocking Peptide

Full Product Name

POLR2I Blocking Peptide

Product Gene Name

POLR2I blocking peptide

Product Synonym Names

DNA directed RNA polymerase II 14.5 kDa polypeptide; DNA directed RNA polymerase II polypeptide I; DNA directed RNA polymerase II subunit I; DNA directed RNA polymerase II subunit RPB9; DNA-directed RNA polymerase II subunit I; DNA-directed RNA polymerase II subunit RPB9; hRPB14.5; POLR2I; Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa; RNA polymerase II 14.5 kDa subunit; RNA polymerase II subunit B9; RPB14.5; RPB9; RPB9_HUMAN

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

POLR2I peptide (MBS9626040) is used for blocking the activity of POLR2I antibody (MBS9607324)

Molecular Weight

14,523 Da

OMIM

180662

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for POLR2I blocking peptide

Blocking/Control

Other Notes

Small volumes of POLR2I blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POLR2I purchase

MBS9626040 is a blocking peptide targeting POLR2I.

Additional Details

NCBI/Uniprot data below describe general gene information for POLR2I. It may not necessarily be applicable to this product.

NCBI GI #

5453930

NCBI GeneID

5438

NCBI Accession #

NP_006224.1

UniProt Primary Accession #

P36954

UniProt Secondary Accession #

Q6NW05; B2R5J2

UniProt Related Accession #

P36954

GenBank Nucleotide #

NM_006233.4

NCBI Official Full Name

Homo sapiens polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa (POLR2I), mRNA

NCBI Official Synonym Full Names

polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

NCBI Official Symbol

POLR2I

NCBI Official Synonym Symbols

RPB9; hRPB14.5

UniProt Protein Name

DNA-directed RNA polymerase II subunit RPB9

UniProt Synonym Protein Names

DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit; RPB14.5

UniProt Gene Name

POLR2I

UniProt Synonym Gene Names

RNA polymerase II subunit B9; RPB14.5

UniProt Entry Name

RPB9_HUMAN

NCBI Protein Information

DNA-directed RNA polymerase II subunit RPB9; DNA-directed RNA polymerase II 14.5 kDa polypeptide; DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit; RNA polymerase II subunit B9; RPB14.5

NCBI Summary for POLR2I

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008]

UniProt Comments for POLR2I

POLR2I: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

Protein type: Nucleotide Metabolism - pyrimidine; Transcription initiation complex; Transferase; Nucleotide Metabolism - purine; RNA processing; EC 2.7.7.6

Chromosomal Location of Human Ortholog: 19q12

Cellular Component: nucleoplasm; DNA-directed RNA polymerase II, core complex; nucleus

Molecular Function: DNA binding; zinc ion binding; DNA-directed RNA polymerase activity

Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; mRNA capping; viral reproduction; nucleotide-excision repair; positive regulation of viral transcription; somatic stem cell maintenance; RNA splicing; transcription-coupled nucleotide-excision repair; RNA elongation from RNA polymerase II promoter; gene expression; DNA repair

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with POLR2I blocking peptide

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Eukaryotic Transcription Initiation Pathway antibodies	Eukaryotic Transcription Initiation Pathway Diagram
Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies	Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram