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PP5 Antibody (C-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9231570

PPP5C belongs to the PPP phosphatase family, PP-T subfamily, and may play a role in the regulation of RNA biogenesis and/or mitosis. In vitro,PPP5C dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1. More details

$455 / 0.5 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PP5, Blocking Peptide
Full Product Name
PP5 Antibody (C-term) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
PPP5C
Product Synonym Names
Serine/threonine-protein phosphatase 5; PP5; Protein phosphatase T; PP-T; PPT; PPP5C; PPP5
Form/Format
Lyophilized with 100% acetonitrile and is supplied as a powder.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human PPP5C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
PP5 peptide (MBS9231570) is used for blocking the activity of PP5 (PP5C) antibody (MBS9202924)
OMIM
600658
Reconstitution
Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.

Other Notes

Small volumes of PP5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PP5 purchase

MBS9231570 is a blocking peptide targeting PP5. Also known as PP5 Antibody (C-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for PP5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein phosphatase 5 isoform 1
NCBI Official Synonym Full Names
protein phosphatase 5 catalytic subunit
NCBI Official Symbol
PPP5C
NCBI Official Synonym Symbols
PP5; PPT; PPP5
UniProt Protein Name
Serine/threonine-protein phosphatase 5
UniProt Synonym Protein Names
Protein phosphatase T
UniProt Gene Name
PPP5C
UniProt Synonym Gene Names
PPP5; PP5; PP-T; PPT
UniProt Entry Name
PPP5_HUMAN
NCBI Protein Information
serine/threonine-protein phosphatase 5

NCBI Summary for PP5

This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
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UniProt Comments for PP5

Function: May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1.

Catalytic activity: A phosphoprotein + H2O = a protein + phosphate.

Cofactor: Binds 1 iron ion per subunit

By similarity.Binds 1 manganese ion per subunit

By similarity.

Subunit structure: Interacts with CDC16 and CDC27. Ref.8

Subcellular location: Nucleus. Cytoplasm. Note: Predominantly nuclear. But also present in the cytoplasm.

Tissue specificity: Ubiquitous.

Sequence similarities: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.Contains 3 TPR repeats.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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