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Mouse Prkx Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9220445

Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis.… More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prkx, Blocking Peptide
Full Product Name
Mouse Prkx Antibody (N-term) Blocking peptide
Product Gene Name
Prkx blocking peptide
Product Synonym Gene Name
Pkare
Product Synonym Names
cAMP-dependent protein kinase catalytic subunit PRKX; PrKX; Protein kinase X; Protein kinase X-linked; Serine/threonine-protein kinase PRKX; PKA-related protein kinase; Prkx; Pkare
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of Mouse Prkx. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
Prkx peptide (MBS9220445) is used for blocking the activity of Prkx antibody (MBS9211226)
Molecular Weight
40,467 Da
Cellular Location
Cytoplasm. Nucleus. Note: cAMP induces nuclear translocation
Tissue Location
Widely expressed.

Other Notes

Small volumes of Prkx blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Prkx purchase

MBS9220445 is a blocking peptide targeting Prkx. Also known as Mouse Prkx Antibody (N-term) Blocking peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for Prkx. It may not necessarily be applicable to this product.

NCBI GI #
41017499
NCBI GeneID
19108
NCBI Accession #
Q922R0.1
UniProt Primary Accession #
Q922R0
UniProt Secondary Accession #
Q3UCD1; Q8BHD6; Q9QZ12; B1AVU0
UniProt Related Accession #
Q922R0
NCBI Official Full Name
cAMP-dependent protein kinase catalytic subunit PRKX
NCBI Official Synonym Full Names
protein kinase, X-linked
NCBI Official Symbol
Prkx
NCBI Official Synonym Symbols
PKX1; Pkare
UniProt Protein Name
cAMP-dependent protein kinase catalytic subunit PRKX
UniProt Synonym Protein Names
PKA-related protein kinase
Protein Family
cAMP-dependent protein kinase
UniProt Gene Name
Prkx
UniProt Synonym Gene Names
Pkare; PrKX; Protein kinase X; Protein kinase X-linked; Serine/threonine-protein kinase PRKX
UniProt Entry Name
PRKX_MOUSE
NCBI Protein Information
cAMP-dependent protein kinase catalytic subunit PRKX

UniProt Comments for Prkx

PRKX: Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation. A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

Protein type: EC 2.7.11.1; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; PKA family

Cellular Component: cytoplasm; nucleus

Molecular Function: cAMP-dependent protein kinase activity; protein serine/threonine kinase activity

Biological Process: angiogenesis; cell adhesion; cell-substrate adhesion; endothelial cell migration; endothelial cell proliferation; myeloid cell differentiation; peptidyl-serine phosphorylation; protein amino acid autophosphorylation; regulation of cell adhesion; regulation of cell migration
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Research Articles on Prkx

1. The interaction of PRKX with Pin-1, Magi-1 and Bag-3 could contribute to the stimulating role of PRKX in angiogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Prkx blocking peptide

 Reference Product  PubMed Publications
 Prkar1a blocking peptide  >1 publications with Prkx and Prkar1a

Pathways associated with Prkx blocking peptide

 Products by Pathway  Pathway Diagram
 Apoptosis Signaling Pathway antibodies  Apoptosis Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with Prkx blocking peptide

 Disease Name  Pubmed Publications
 Chromosome Aberrations Antibodies  >9 publications with Prkx and Chromosome Aberrations
 Urogenital Abnormalities Antibodies  >6 publications with Prkx and Urogenital Abnormalities
 Kidney Diseases Antibodies  >6 publications with Prkx and Kidney Diseases
 Disease Models, Animal Antibodies  >3 publications with Prkx and Disease Models, Animal
 Nervous System Diseases Antibodies  >3 publications with Prkx and Nervous System Diseases
 Heart Diseases Antibodies  >1 publications with Prkx and Heart Diseases
 Inflammation Antibodies  >1 publications with Prkx and Inflammation
 Fatty Liver Antibodies  >1 publications with Prkx and Fatty Liver
 Cell Transformation, Neoplastic Antibodies  >1 publications with Prkx and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >1 publications with Prkx and Liver Diseases

Organs/Tissues associated with Prkx blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >11 publications with Prkx and Kidney
 Heart Antibodies  >6 publications with Prkx and Heart
 Embryonic Tissue Antibodies  >6 publications with Prkx and Embryonic Tissue
 Lung Antibodies  >4 publications with Prkx and Lung
 Bone Antibodies  >3 publications with Prkx and Bone
 Brain Antibodies  >3 publications with Prkx and Brain
 Spleen Antibodies  >2 publications with Prkx and Spleen
 Connective Tissue Antibodies  >2 publications with Prkx and Connective Tissue
 Thymus Antibodies  >1 publications with Prkx and Thymus
 Ovary Antibodies  >1 publications with Prkx and Ovary
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