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PYDC1 Antibody (Center) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9219677

Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase… More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PYDC1, Blocking Peptide
Full Product Name
PYDC1 Antibody (Center) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
ASC2; ASCI; POP1; PYC1
Product Synonym Names
Pyrin domain-containing protein 1; PAAD-only protein 1; Pyrin-only protein 1; PYDC1; ASC2; ASCI; POP1; PYC1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of PYDC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
PYDC1 peptide (MBS9219677) is used for blocking the activity of PYDC1 antibody (MBS9213649)
Molecular Weight
10,107 Da
OMIM
615700
Cellular Location
Cytoplasm.
Tissue Location
Predominantly expressed in monocytes, macrophages and granulocytes.

Other Notes

Small volumes of PYDC1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PYDC1 purchase

MBS9219677 is a blocking peptide targeting PYDC1. Also known as PYDC1 Antibody (Center) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for PYDC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Pyrin domain-containing protein 1
NCBI Official Synonym Full Names
pyrin domain containing 1
NCBI Official Symbol
PYDC1
NCBI Official Synonym Symbols
ASC2; POP1; PYC1; cPOP1
UniProt Protein Name
Pyrin domain-containing protein 1
UniProt Synonym Protein Names
PAAD-only protein 1
UniProt Gene Name
PYDC1
UniProt Synonym Gene Names
cPOP1
UniProt Entry Name
PYDC1_HUMAN
NCBI Protein Information
pyrin domain-containing protein 1

UniProt Comments for PYDC1

PYDC1: Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytosol; IkappaB kinase complex; nucleus

Molecular Function: protein binding

Biological Process: inhibition of NF-kappaB transcription factor; innate immune response; negative regulation of interleukin-1 beta secretion; negative regulation of protein kinase activity; positive regulation of interleukin-1 beta secretion; tumor necrosis factor-mediated signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PYDC1 blocking peptide

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with PYDC1 and Inflammation
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