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RAD Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9624276

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAD, Blocking Peptide
Full Product Name
RAD Blocking Peptide
Product Gene Name
RAD blocking peptide
Product Synonym Gene Name
RRAD
Product Synonym Names
GTP binding protein RAD; GTP-binding protein RAD; RAD; RAD_HUMAN; RAD1; RAS (RAD and GEM) like GTP binding 3; Ras associated with diabetes; Ras related associated with diabetes; REM3; RRAD
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
RAD peptide (MBS9624276) is used for blocking the activity of RAD antibody (MBS9605559)
Molecular Weight
33,245 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (66955582..66959439, complement). Location: 16q22
OMIM
179503
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for RAD blocking peptide
Blocking/Control

Other Notes

Small volumes of RAD blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAD purchase

MBS9624276 is a blocking peptide targeting RAD.

Additional Details

NCBI/Uniprot data below describe general gene information for RAD. It may not necessarily be applicable to this product.

NCBI GI #
192807327
NCBI GeneID
6236
NCBI Accession #
NP_001122322.1
UniProt Primary Accession #
P55042
UniProt Secondary Accession #
Q96F39
UniProt Related Accession #
P55042
GenBank Nucleotide #
NM_001128850.1
NCBI Official Full Name
GTP-binding protein RAD
NCBI Official Synonym Full Names
Ras-related associated with diabetes
NCBI Official Symbol
RRAD
NCBI Official Synonym Symbols
RAD; RAD1; REM3
UniProt Protein Name
GTP-binding protein RAD
UniProt Synonym Protein Names
RAD1; Ras associated with diabetes
Protein Family
Transcription factor
UniProt Gene Name
RRAD
UniProt Synonym Gene Names
RAD
UniProt Entry Name
RAD_HUMAN
NCBI Protein Information
GTP-binding protein RAD; ras associated with diabetes; RAS (RAD and GEM) like GTP binding 3

UniProt Comments for RAD

RRAD: a small G protein of the RGK family. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Interacts with calmodulin preferentially in the inactive, GDP-bound form. Interacts with CAMK2D and CACNB2. Interaction with CACNB2 regulates the trafficking of CACNA1C to the cell membrane. Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.

Protein type: G protein, monomeric, RGK; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 16q22

Cellular Component: plasma membrane

Molecular Function: calmodulin binding; GTPase activity; protein binding; GTP binding

Biological Process: metabolic process; small GTPase mediated signal transduction
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Research Articles on RAD

1. Rad over expression could be a molecular target to improve bortezomib sensitivity in human leukemia and lymphoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAD blocking peptide

 Reference Product  PubMed Publications
 NME1 blocking peptide  >2 publications with RAD and NME1

Pathways associated with RAD blocking peptide

 Products by Pathway  Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram

Diseases associated with RAD blocking peptide

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with RAD and Neoplasms
 Cardiovascular Diseases Antibodies  >7 publications with RAD and Cardiovascular Diseases
 Carcinoma Antibodies  >6 publications with RAD and Carcinoma
 Nervous System Diseases Antibodies  >5 publications with RAD and Nervous System Diseases
 Disease Models, Animal Antibodies  >5 publications with RAD and Disease Models, Animal
 Lung Neoplasms Antibodies  >3 publications with RAD and Lung Neoplasms
 Inflammation Antibodies  >3 publications with RAD and Inflammation
 Carcinoma, Non-Small-Cell Lung Antibodies  >3 publications with RAD and Carcinoma, Non-Small-Cell Lung
 Liver Neoplasms Antibodies  >2 publications with RAD and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with RAD and Liver Diseases

Organs/Tissues associated with RAD blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >36 publications with RAD and Muscle
 Heart Antibodies  >14 publications with RAD and Heart
 Embryonic Tissue Antibodies  >4 publications with RAD and Embryonic Tissue
 Brain Antibodies  >4 publications with RAD and Brain
 Lung Antibodies  >4 publications with RAD and Lung
 Connective Tissue Antibodies  >3 publications with RAD and Connective Tissue
 Kidney Antibodies  >3 publications with RAD and Kidney
 Prostate Antibodies  >2 publications with RAD and Prostate
 Pancreas Antibodies  >2 publications with RAD and Pancreas
 Liver Antibodies  >2 publications with RAD and Liver
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