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Phospho-SRC3 (Thr24) Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9615296

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRC-3, Blocking Peptide
Full Product Name
Phospho-SRC3 (Thr24) Blocking Peptide
Product Gene Name
SRC-3 blocking peptide
Product Synonym Gene Name
NCOA3
Product Synonym Names
ACTR; AIB 1; AIB-1; AIB1; Amplified in breast cancer 1; Amplified in breast cancer 1 protein; bHLHe42; CAGH 16; CAGH16; CBP interacting protein; CBP-interacting protein; Class E basic helix-loop-helix protein 42; CTG 26; CTG26; KAT13B/AIB1; MGC141848; NCOA 3; NCoA-3; Ncoa3; NCOA3_HUMAN; Nuclear receptor coactivator 3; pCIP; RAC 3; RAC-3; RAC3; Receptor associated coactivator 3; Receptor-associated coactivator 3; SRC 3; SRC-3; SRC3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM 1; TRAM-1; TRAM1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
SRC3 (Thr24) peptide (MBS9615296) is used for blocking the activity of SRC3 (Thr24) antibody (MBS9600740)
Molecular Weight
154,892 Da
OMIM
601937
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for SRC-3 blocking peptide
Blocking/Control

Other Notes

Small volumes of SRC-3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRC-3 purchase

MBS9615296 is a blocking peptide targeting SRC-3. Also known as Phospho-SRC3 (Thr24) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for SRC-3. It may not necessarily be applicable to this product.

NCBI GI #
291490685
NCBI GeneID
8202
NCBI Accession #
NP_001167559.1
UniProt Primary Accession #
Q9Y6Q9
UniProt Secondary Accession #
Q0VF45; Q5JYD9; Q5JYE0; Q9BR49; Q9UPC9; Q9UPG4; Q9UPG7; A4LAZ5
UniProt Related Accession #
Q9Y6Q9
GenBank Nucleotide #
NM_001174088.1
NCBI Official Full Name
nuclear receptor coactivator 3 isoform d
NCBI Official Synonym Full Names
nuclear receptor coactivator 3
NCBI Official Symbol
NCOA3
NCBI Official Synonym Symbols
ACTR; AIB1; RAC3; SRC3; pCIP; AIB-1; CTG26; SRC-3; CAGH16; KAT13B; TNRC14; TNRC16; TRAM-1; bHLHe42
UniProt Protein Name
Nuclear receptor coactivator 3
UniProt Synonym Protein Names
ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42; bHLHe42; Receptor-associated coactivator 3; RAC-3; Steroid receptor coactivator protein 3; SRC-3; Thyroid hormone receptor activator molecule 1
UniProt Gene Name
NCOA3
UniProt Synonym Gene Names
AIB1; BHLHE42; RAC3; TRAM1; NCoA-3; AIB-1; pCIP; bHLHe42; RAC-3; SRC-3; TRAM-1
UniProt Entry Name
NCOA3_HUMAN
NCBI Protein Information
nuclear receptor coactivator 3; CBP-interacting protein; amplified in breast cancer 1 protein; class E basic helix-loop-helix protein 42; receptor-associated coactivator 3; steroid receptor coactivator protein 3; thyroid hormone receptor activator molecul

NCBI Summary for SRC-3

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
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Research Articles on SRC-3

1. Results indicate a combination of decreased expression of ERs, AR and SRC-3 but not SRC-1 may be involved in the tumorigenesis of gliomas, ERalpha/SRC-3 axis may play central role in the regulation these tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SRC-3 blocking peptide

 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 Retinoic Acid Receptors-mediated Signaling Pathway antibodies  Retinoic Acid Receptors-mediated Signaling Pathway Diagram

Diseases associated with SRC-3 blocking peptide

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >127 publications with SRC-3 and Breast Neoplasms
 Adenocarcinoma Antibodies  >28 publications with SRC-3 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >19 publications with SRC-3 and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >16 publications with SRC-3 and Prostatic Neoplasms
 Disease Models, Animal Antibodies  >13 publications with SRC-3 and Disease Models, Animal
 Ovarian Neoplasms Antibodies  >12 publications with SRC-3 and Ovarian Neoplasms
 Hyperplasia Antibodies  >11 publications with SRC-3 and Hyperplasia
 Liver Neoplasms Antibodies  >11 publications with SRC-3 and Liver Neoplasms
 Inflammation Antibodies  >10 publications with SRC-3 and Inflammation
 Liver Diseases Antibodies  >10 publications with SRC-3 and Liver Diseases

Organs/Tissues associated with SRC-3 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >30 publications with SRC-3 and Blood
 Liver Antibodies  >29 publications with SRC-3 and Liver
 Prostate Antibodies  >28 publications with SRC-3 and Prostate
 Thyroid Antibodies  >21 publications with SRC-3 and Thyroid
 Lymph Antibodies  >19 publications with SRC-3 and Lymph
 Lymph Node Antibodies  >19 publications with SRC-3 and Lymph Node
 Lung Antibodies  >17 publications with SRC-3 and Lung
 Uterus Antibodies  >17 publications with SRC-3 and Uterus
 Brain Antibodies  >16 publications with SRC-3 and Brain
 Muscle Antibodies  >16 publications with SRC-3 and Muscle
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