TACC2 Blocking Peptide – Cat# MBS9622377

TACC2 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: TACC2 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9622377
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9622377

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TACC2, Blocking Peptide

Full Product Name

TACC2 Blocking Peptide

Product Gene Name

TACC2 blocking peptide

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

TACC2 peptide (MBS9622377) is used for blocking the activity of TACC2 antibody (MBS9612433)

Molecular Weight

2948

OMIM

605302

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for TACC2 blocking peptide

Blocking/Control

Other Notes

Small volumes of TACC2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TACC2 purchase

MBS9622377 is a blocking peptide targeting TACC2.

Additional Details

NCBI/Uniprot data below describe general gene information for TACC2. It may not necessarily be applicable to this product.

NCBI GI #

122066295

NCBI GeneID

10579

NCBI Accession #

O95359.3

UniProt Primary Accession #

O95359

UniProt Secondary Accession #

Q4VXL0; Q4VXL3; Q4VXL6; Q4VXL7; Q5U5T7; Q86WG6; Q86WG7; Q8TCK9; Q9BVQ1; Q9NZ41; Q9NZR5

UniProt Related Accession #

O95359

NCBI Official Full Name

Transforming acidic coiled-coil-containing protein 2

NCBI Official Synonym Full Names

transforming, acidic coiled-coil containing protein 2

NCBI Official Symbol

TACC2

NCBI Official Synonym Symbols

AZU-1; ECTACC

UniProt Protein Name

Transforming acidic coiled-coil-containing protein 2

UniProt Synonym Protein Names

Anti-Zuai-1; AZU-1

Protein Family

Transforming acidic coiled-coil-containing protein

UniProt Gene Name

TACC2

UniProt Synonym Gene Names

AZU-1

UniProt Entry Name

TACC2_HUMAN

NCBI Protein Information

transforming acidic coiled-coil-containing protein 2; anti zuai-1

NCBI Summary for TACC2

Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for TACC2

TACC2: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. Belongs to the TACC family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: microtubule cytoskeleton; nucleoplasm; cytoplasm; nucleolus; microtubule organizing center; nucleus

Molecular Function: protein domain specific binding; nuclear hormone receptor binding

Biological Process: cell proliferation; regulation of microtubule-based process; astral microtubule organization and biogenesis; neurogenesis; cerebral cortex development; microtubule cytoskeleton organization and biogenesis; interkinetic nuclear migration

Research Articles on TACC2

1. Data suggest that TACC2 is highly expressed in prostate cancer cells and contributes to cell cycle progression and cell proliferation in androgen-nonresponsive prostate cancer cells; overexpression of TACC2 leads to recurrence of prostate cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with TACC2 blocking peptide

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>7 publications with TACC2 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>2 publications with TACC2 and Cardiovascular Diseases
Neutropenia Antibodies	>1 publications with TACC2 and Neutropenia
Nervous System Diseases Antibodies	>1 publications with TACC2 and Nervous System Diseases
Anemia Antibodies	>1 publications with TACC2 and Anemia
Heart Diseases Antibodies	>1 publications with TACC2 and Heart Diseases
Precancerous Conditions Antibodies	>1 publications with TACC2 and Precancerous Conditions
Necrosis Antibodies	>1 publications with TACC2 and Necrosis
Hyperplasia Antibodies	>1 publications with TACC2 and Hyperplasia

Organs/Tissues associated with TACC2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>5 publications with TACC2 and Kidney
Prostate Antibodies	>4 publications with TACC2 and Prostate
Heart Antibodies	>4 publications with TACC2 and Heart
Muscle Antibodies	>4 publications with TACC2 and Muscle
Brain Antibodies	>4 publications with TACC2 and Brain
Mammary Gland Antibodies	>3 publications with TACC2 and Mammary Gland
Embryonic Tissue Antibodies	>2 publications with TACC2 and Embryonic Tissue
Bone Antibodies	>2 publications with TACC2 and Bone
Testis Antibodies	>1 publications with TACC2 and Testis
Vascular Antibodies	>1 publications with TACC2 and Vascular