TDRD1 Blocking Peptide

Name: TDRD1 Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS544554
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS544554

Antigenic Blocking Peptide Tudor domain-containing protein 1Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the… More details

$315 / 0.25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TDRD1, Blocking Peptide

Full Product Name

TDRD1 Peptide

Product Gene Name

TDRD1 blocking peptide

Product Synonym Names

Cancer/testis antigen 41.1; CT41.1; FLJ21082; MTR 1; Tudor domain containing protein 1 antibody

Form/Format

Antigenic Blocking Peptide

Concentration

Quantity: 250 ug; Volume: 100 ul (lot specific)

Preparation and Storage

-20 degree C for long term storage

Antibody/Peptide Pairs

TDRD1 peptide (MBS544554) is used for blocking the activity of TDRD1 antibody (MBS540240)

Antibody/Peptide Pairs

TDRD1 peptide (MBS544554) is used for blocking the activity of TDRD1 antibody (MBS5400040)

Molecular Weight

79,170 Da

OMIM

605796

Immunogen

Synthetic Peptide

Expression

Testis and ovary specific. Also expressed in several cancers.

Molecular Function

metal ion binding

Subcellular Location

Cytoplasm (Note: Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Also present in chromatoid body)

Applications Tested/Suitable for TDRD1 blocking peptide

Immunocompeition, Immunodepletion

Application Notes for TDRD1 blocking peptide

Western Blot: 1:500

Other Notes

Small volumes of TDRD1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TDRD1 purchase

MBS544554 is a blocking peptide targeting TDRD1. Also known as TDRD1 Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for TDRD1. It may not necessarily be applicable to this product.

NCBI GI #

194385600

NCBI GeneID

56165

NCBI Accession #

BAG65177.1

UniProt Primary Accession #

Q9BXT4

UniProt Secondary Accession #

Q4G0Y8; Q6P518; Q9H7B3; A6NEN3; A6NMN2; B3KVI4; B4E2L5; D3DRC2

UniProt Related Accession #

Q9BXT4

NCBI Official Full Name

unnamed protein product

NCBI Official Synonym Full Names

tudor domain containing 1

NCBI Official Symbol

TDRD1

NCBI Official Synonym Symbols

CT41.1

UniProt Protein Name

Tudor domain-containing protein 1

UniProt Synonym Protein Names

Cancer/testis antigen 41.1; CT41.1

Protein Family

Tudor domain-containing protein

UniProt Gene Name

TDRD1

UniProt Synonym Gene Names

CT41.1

UniProt Entry Name

TDRD1_HUMAN

NCBI Protein Information

tudor domain-containing protein 1

NCBI Summary for TDRD1

This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for TDRD1

TDRD1: Plays a central role during spermatogenesis by participating in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins. Belongs to the TDRD1 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: cytoplasm

Molecular Function: metal ion binding; protein binding

Biological Process: DNA methylation during gametogenesis; germ cell development; meiotic cell cycle; multicellular organismal development; RNA-mediated gene silencing; spermatogenesis

Research Articles on TDRD1

1. ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TDRD1 blocking peptide

Reference Product	PubMed Publications
PIWIL2 blocking peptide	>13 publications with TDRD1 and PIWIL2
PIWIL1 blocking peptide	>11 publications with TDRD1 and PIWIL1
PIWIL4 blocking peptide	>6 publications with TDRD1 and PIWIL4
DDX4 blocking peptide	>5 publications with TDRD1 and DDX4
NANOS2 blocking peptide	>1 publications with TDRD1 and NANOS2
ASZ1 blocking peptide	>1 publications with TDRD1 and ASZ1
MOV10L1 blocking peptide	>1 publications with TDRD1 and MOV10L1

Pathways associated with TDRD1 blocking peptide

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Gene Silencing By RNA Pathway antibodies	Gene Silencing By RNA Pathway Diagram
PIWI-interacting RNA (piRNA) Biogenesis Pathway antibodies	PIWI-interacting RNA (piRNA) Biogenesis Pathway Diagram

Diseases associated with TDRD1 blocking peptide

Disease Name	Pubmed Publications
Infertility, Female Antibodies	>2 publications with TDRD1 and Infertility, Female
Adenocarcinoma Antibodies	>1 publications with TDRD1 and Adenocarcinoma
Cell Transformation, Neoplastic Antibodies	>1 publications with TDRD1 and Cell Transformation, Neoplastic
Hyperplasia Antibodies	>1 publications with TDRD1 and Hyperplasia
Neoplasm Metastasis Antibodies	>1 publications with TDRD1 and Neoplasm Metastasis

Organs/Tissues associated with TDRD1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>17 publications with TDRD1 and Testis
Prostate Antibodies	>8 publications with TDRD1 and Prostate
Liver Antibodies	>2 publications with TDRD1 and Liver
Brain Antibodies	>2 publications with TDRD1 and Brain