TLK2 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: TLK2 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9624649
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9624649

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TLK2, Blocking Peptide

Full Product Name

TLK2 Blocking Peptide

Product Gene Name

TLK2 blocking peptide

Product Synonym Names

MGC44450; PKU alpha; PKU-alpha; Serine/threonine kinase; Serine/threonine protein kinase tousled like 2; Serine/threonine-protein kinase tousled-like 2; TLK 2; tlk2; TLK2_HUMAN; Tousled like kinase 2; Tousled-like kinase 2

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

TLK2 peptide (MBS9624649) is used for blocking the activity of TLK2 antibody (MBS9605932)

Molecular Weight

87,661 Da

OMIM

608439

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for TLK2 blocking peptide

Blocking/Control

Other Notes

Small volumes of TLK2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLK2 purchase

MBS9624649 is a blocking peptide targeting TLK2.

Additional Details

NCBI/Uniprot data below describe general gene information for TLK2. It may not necessarily be applicable to this product.

NCBI GI #

547235496

NCBI GeneID

11011

NCBI Accession #

NP_001271262.1

UniProt Primary Accession #

Q86UE8

UniProt Secondary Accession #

Q9UKI7; Q9Y4F7; D3DU07

UniProt Related Accession #

Q86UE8

GenBank Nucleotide #

NM_001284333.1

NCBI Official Full Name

serine/threonine-protein kinase tousled-like 2 isoform C

NCBI Official Synonym Full Names

tousled-like kinase 2

NCBI Official Symbol

TLK2

NCBI Official Synonym Symbols

HsHPK; PKU-ALPHA

UniProt Protein Name

Serine/threonine-protein kinase tousled-like 2

UniProt Synonym Protein Names

HsHPK; PKU-alpha; Tousled-like kinase 2

Protein Family

Serine/threonine-protein kinase tousled

UniProt Gene Name

TLK2

UniProt Entry Name

TLK2_HUMAN

NCBI Protein Information

serine/threonine-protein kinase tousled-like 2

UniProt Comments for TLK2

TLK2: Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, Other; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Other group; TLK family

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: perinuclear region of cytoplasm; intermediate filament; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding

Biological Process: negative regulation of autophagy; peptidyl-serine phosphorylation; regulation of chromatin assembly or disassembly; chromatin modification; cell cycle; protein amino acid phosphorylation; response to DNA damage stimulus; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; chromosome segregation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TLK2 blocking peptide

Reference Product	PubMed Publications
ASF1A blocking peptide	>2 publications with TLK2 and ASF1A
ASF1B blocking peptide	>2 publications with TLK2 and ASF1B

Pathways associated with TLK2 blocking peptide

Products by Pathway	Pathway Diagram
DNA Damage Response Pathway antibodies	DNA Damage Response Pathway Diagram

Diseases associated with TLK2 blocking peptide

Disease Name	Pubmed Publications
Abnormalities, Multiple Antibodies	>1 publications with TLK2 and Abnormalities, Multiple
Mental Disorders Antibodies	>1 publications with TLK2 and Mental Disorders
Infertility, Male Antibodies	>1 publications with TLK2 and Infertility, Male

Organs/Tissues associated with TLK2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with TLK2 and Brain
Blood Antibodies	>1 publications with TLK2 and Blood
Prostate Antibodies	>1 publications with TLK2 and Prostate
Connective Tissue Antibodies	>1 publications with TLK2 and Connective Tissue
Testis Antibodies	>1 publications with TLK2 and Testis