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TOB1 Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9227709

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TOB1, Blocking Peptide
Full Product Name
TOB1 Antibody (N-term) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
TOB; TROB1
Product Synonym Names
Protein Tob1; Transducer of erbB-2 1; TOB1; TOB; TROB1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human TOB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
TOB1 peptide (MBS9227709) is used for blocking the activity of TOB1 antibody (MBS9213306)
Molecular Weight
38,155 Da
OMIM
605523
Cellular Location
Cytoplasm. Nucleus. Note: Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic.
Tissue Location
Ubiquitous.

Other Notes

Small volumes of TOB1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOB1 purchase

MBS9227709 is a blocking peptide targeting TOB1. Also known as TOB1 Antibody (N-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for TOB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Protein Tob1
NCBI Official Synonym Full Names
transducer of ERBB2, 1
NCBI Official Symbol
TOB1
NCBI Official Synonym Symbols
TOB; TROB; APRO5; APRO6; PIG49; TROB1
UniProt Protein Name
Protein Tob1
UniProt Synonym Protein Names
Transducer of erbB-2 1
Protein Family
UniProt Gene Name
TOB1
UniProt Synonym Gene Names
TOB; TROB1
UniProt Entry Name
TOB1_HUMAN
NCBI Protein Information
protein Tob1

NCBI Summary for TOB1

This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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UniProt Comments for TOB1

TOB1: Anti-proliferative protein that interacts with the erbB- 2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. Belongs to the BTG family.

Protein type: Adaptor/scaffold; Cell cycle regulation

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: CCR4-NOT complex

Molecular Function: protein binding; receptor tyrosine kinase binding; SH3/SH2 adaptor activity

Biological Process: negative regulation of cell proliferation; negative regulation of translation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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