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VAPA Antibody(c-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9224319

MBS9224319 is a blocking peptide targeting VAPA. Also known as VAPA Antibody(C-term) Blocking peptide. May play a role in vesicle trafficking. More details

$455 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VAPA, Blocking Peptide
Full Product Name
VAPA Antibody(C-term) Blocking peptide
Product Gene Name
VAPA blocking peptide
Product Synonym Gene Name
VAP33
Product Synonym Names
Vesicle-associated membrane protein-associated protein A; VAMP-A; VAMP-associated protein A; VAP-A; 33 kDa VAMP-associated protein; VAP-33; VAPA; VAP33
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
VAPA peptide (MBS9224319) is used for blocking the activity of VAPA antibody (MBS9206569)
Molecular Weight
32,614 Da
OMIM
605703
Cellular Location
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note: Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells
Tissue Location
Ubiquitous.

Other Notes

Small volumes of VAPA blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VAPA. It may not necessarily be applicable to this product.

NCBI GI #
122066680
NCBI GeneID
9218
NCBI Accession #
Q9P0L0.3
UniProt Primary Accession #
Q9P0L0
UniProt Secondary Accession #
O75453; Q5U0E7; Q9UBZ2; A6NDZ0; D3DUI3
UniProt Related Accession #
Q9P0L0
NCBI Official Full Name
Vesicle-associated membrane protein-associated protein A
NCBI Official Synonym Full Names
VAMP associated protein A
NCBI Official Symbol
VAPA
NCBI Official Synonym Symbols
VAP-A; VAP33; VAP-33; hVAP-33
UniProt Protein Name
Vesicle-associated membrane protein-associated protein A
UniProt Synonym Protein Names
33 kDa VAMP-associated protein; VAP-33
Protein Family
Vesicle-associated membrane protein-associated protein
UniProt Gene Name
VAPA
UniProt Synonym Gene Names
VAP33; VAMP-A; VAMP-associated protein A; VAP-A; VAP-33
UniProt Entry Name
VAPA_HUMAN
NCBI Protein Information
vesicle-associated membrane protein-associated protein A

NCBI Summary for VAPA

The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for VAPA

VAPA: May play a role in vesicle trafficking. Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18p11.22

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; perinuclear region of cytoplasm; plasma membrane; tight junction; vesicle

Molecular Function: FFAT motif binding; microtubule binding; protein binding; protein domain specific binding; protein heterodimerization activity; signal transducer activity

Biological Process: cell death; endoplasmic reticulum organization and biogenesis; ER to Golgi vesicle-mediated transport; neurite development; positive regulation of I-kappaB kinase/NF-kappaB cascade; sphingolipid biosynthetic process
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Research Articles on VAPA

1. The effects of sterol manipulation of HuH7 cells on complexes of established sterol-binding Oxysterol-binding protein related proteins with their endoplasmic reticulum receptor, VAMP-associated protein A (VAPA), were examined.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VAPA blocking peptide

 Products by Pathway  Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid De Novo Biosynthesis Pathway antibodies  Sphingolipid De Novo Biosynthesis Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Diseases associated with VAPA blocking peptide

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >35 publications with VAPA and Lung Diseases
 Nervous System Diseases Antibodies  >25 publications with VAPA and Nervous System Diseases
 Death Antibodies  >8 publications with VAPA and Death
 Immune System Diseases Antibodies  >8 publications with VAPA and Immune System Diseases
 Inflammation Antibodies  >7 publications with VAPA and Inflammation
 Necrosis Antibodies  >7 publications with VAPA and Necrosis
 Disease Models, Animal Antibodies  >6 publications with VAPA and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >4 publications with VAPA and Cardiovascular Diseases
 Weight Loss Antibodies  >3 publications with VAPA and Weight Loss
 Edema Antibodies  >2 publications with VAPA and Edema

Organs/Tissues associated with VAPA blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >57 publications with VAPA and Blood
 Brain Antibodies  >24 publications with VAPA and Brain
 Lung Antibodies  >23 publications with VAPA and Lung
 Liver Antibodies  >17 publications with VAPA and Liver
 Nerve Antibodies  >13 publications with VAPA and Nerve
 Lymph Antibodies  >11 publications with VAPA and Lymph
 Lymph Node Antibodies  >11 publications with VAPA and Lymph Node
 Spleen Antibodies  >10 publications with VAPA and Spleen
 Bone Antibodies  >8 publications with VAPA and Bone
 Bone Marrow Antibodies  >7 publications with VAPA and Bone Marrow
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