WASF3 Blocking Peptide

Name: WASF3 Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3235627
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3235627

This is a synthetic peptide designed for use in combination with anti-WASF3 antibody madeTarget Description: WASF3 is a member of the Wiskott-Aldrich syndrome protein family. It is a protein that forms a multiprotein complex that links receptor kinases and… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WASF3, Blocking Peptide

Full Product Name

WASF3 Peptide

Product Gene Name

WASF3 blocking peptide

Product Synonym Gene Name

Brush-1; KIAA0900; SCAR3; WAVE3

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

WASF3 peptide (MBS3235627) is used for blocking the activity of WASF3 antibody (MBS3210672)

Molecular Weight

55kDa

OMIM

605068

Product Categories/Family for WASF3 blocking peptide

Peptide

Applications Tested/Suitable for WASF3 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of WASF3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WASF3 purchase

MBS3235627 is a blocking peptide targeting WASF3. Also known as WASF3 Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for WASF3. It may not necessarily be applicable to this product.

NCBI GI #

13699803

NCBI GeneID

10810

NCBI Accession #

NP_006637

UniProt Primary Accession #

Q9UPY6

UniProt Related Accession #

Q9UPY6

GenBank Nucleotide #

NM_006646

NCBI Official Full Name

wiskott-Aldrich syndrome protein family member 3 isoform 1

NCBI Official Synonym Full Names

WASP family member 3

NCBI Official Symbol

WASF3

NCBI Official Synonym Symbols

SCAR3; WAVE3; Brush-1

UniProt Protein Name

Wiskott-Aldrich syndrome protein family member 3

UniProt Synonym Protein Names

Protein WAVE-3; Verprolin homology domain-containing protein 3

Protein Family

Wiskott-Aldrich syndrome protein family

UniProt Gene Name

WASF3

UniProt Synonym Gene Names

KIAA0900; SCAR3; WAVE3; WASP family protein member 3

UniProt Entry Name

WASF3_HUMAN

NCBI Protein Information

wiskott-Aldrich syndrome protein family member 3

NCBI Summary for WASF3

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

UniProt Comments for WASF3

WASF3: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Binds actin and the Arp2/3 complex. Expressed in ovary and brain. Belongs to the SCAR/WAVE family.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: cytoskeleton; lamellipodium; cytoplasm

Molecular Function: actin binding

Biological Process: positive regulation of myelination; lamellipodium biogenesis; regulation of cell shape; actin filament polymerization; protein complex assembly; cytoskeleton organization and biogenesis; oligodendrocyte development

Research Articles on WASF3

1. Study demonstrated that the expression levels of WAVE3 in pancreatic cancer tissues were prominently higher than those in the non-cancerous tissues which seems to be associated with lymphatic metastasis, poorly differentiated tumors. Furthermore, findings suggest that WAVE3 influences cell proliferation, migration and invasion via the AKT pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with WASF3 blocking peptide

Reference Product	PubMed Publications
ACTR3 blocking peptide	>1 publications with WASF3 and ACTR3

Pathways associated with WASF3 blocking peptide

Products by Pathway	Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies	Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies	Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram

Diseases associated with WASF3 blocking peptide

Disease Name	Pubmed Publications
Necrosis Antibodies	>2 publications with WASF3 and Necrosis
Uterine Neoplasms Antibodies	>2 publications with WASF3 and Uterine Neoplasms
Lung Diseases Antibodies	>1 publications with WASF3 and Lung Diseases
Intestinal Neoplasms Antibodies	>1 publications with WASF3 and Intestinal Neoplasms

Organs/Tissues associated with WASF3 blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with WASF3 and Brain
Prostate Antibodies	>4 publications with WASF3 and Prostate
Lung Antibodies	>2 publications with WASF3 and Lung
Bone Antibodies	>1 publications with WASF3 and Bone
Nerve Antibodies	>1 publications with WASF3 and Nerve
Intestine Antibodies	>1 publications with WASF3 and Intestine
Embryonic Tissue Antibodies	>1 publications with WASF3 and Embryonic Tissue
Muscle Antibodies	>1 publications with WASF3 and Muscle
Uterus Antibodies	>1 publications with WASF3 and Uterus