C-Jun ELISA Kit for Cat

Name: Cat C-JUN ELISA Kit; C-Jun; MyBioSource
Brand: MyBioSource
SKU: MBS080671
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS080671

MBS080671 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-Jun, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

C-Jun, ELISA Kit

Full Product Name

Cat C-Jun ELISA Kit

Product Gene Name

C-JUN elisa kit

Species Reactivity

Cat

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

35,629 Da

Chromosome Location

Chromosome: 6; NC_010448.3 (141231122..141232332). Location: chromosome: 6

3D Structure

ModBase 3D Structure for P56432

Other Notes

Small volumes of C-JUN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C-JUN. It may not necessarily be applicable to this product.

NCBI GI #

1911701

NCBI GeneID

396913

NCBI Accession #

AAB50808.1

UniProt Primary Accession #

P56432

UniProt Related Accession #

P56432

NCBI Official Full Name

c-Jun

NCBI Official Symbol

C-JUN

NCBI Official Synonym Symbols

Jun

UniProt Protein Name

Transcription factor AP-1

UniProt Synonym Protein Names

Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog

Protein Family

C-Jun-amino-terminal kinase-interacting protein

UniProt Gene Name

JUN

UniProt Synonym Gene Names

AP1

UniProt Entry Name

JUN_PIG

NCBI Protein Information

transcription factor AP-1; AP1; activator protein 1; proto-oncogene c-jun; V-jun avian sarcoma virus 17 oncogene homolog

UniProt Comments for C-JUN

Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation

By similarity.

Subunit structure: Heterodimer with either FOS or BATF3 or ATF7

By similarity. The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex

By similarity. Interacts with RNF187 and HIPK3

By similarity.

Subcellular location: Nucleus

By similarity.

Post-translational modification: Phosphorylated by CaMK4 and PRKDC; phosphorylation enhances the transcriptional activity. Phosphorylated by HIPK3. Phosphorylated by DYRK2 at Ser-243; this primes the protein for subsequent phosphorylation by GSK3B at Thr-239. Phosphorylated at Thr-239, Ser-243 and Ser-249 by GSK3B; phosphorylation reduces its ability to bind DNA. Phosphorylated by PAK2 at Thr-2, Thr-8, Thr-89, Thr-93 and Thr-286 thereby promoting JUN-mediated cell proliferation and transformation. Phosphorylated by PLK3 following hypoxia or UV irradiation, leading to increase DNA-binding activity

By similarity.Acetylated at Lys-271 by EP300

By similarity.

Sequence similarities: Belongs to the bZIP family. Jun subfamily.Contains 1 bZIP (basic-leucine zipper) domain.

Research Articles on C-JUN

1. The effects of prostaglandin F2alpha administration on transcription factor AP-1 expression and the expression of downstream genes involved in luteolysis are reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with C-JUN elisa kit

Reference Product	PubMed Publications
FOS elisa kit	>6365 publications with C-JUN and FOS
TNF elisa kit	>2606 publications with C-JUN and TNF
EGF elisa kit	>735 publications with C-JUN and EGF
HIF1A elisa kit	>247 publications with C-JUN and HIF1A
IL6 elisa kit	>163 publications with C-JUN and IL6
IL8 elisa kit	>78 publications with C-JUN and IL8
IL1B elisa kit	>43 publications with C-JUN and IL1B
IL12B elisa kit	>18 publications with C-JUN and IL12B
MAPK9 elisa kit	>9 publications with C-JUN and MAPK9
MAPK10 elisa kit	>2 publications with C-JUN and MAPK10

Pathways associated with C-JUN elisa kit

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Diseases associated with C-JUN elisa kit

Disease Name	Pubmed Publications
Death Antibodies	>5411 publications with C-JUN and Death
Nervous System Diseases Antibodies	>4928 publications with C-JUN and Nervous System Diseases
Immune System Diseases Antibodies	>3916 publications with C-JUN and Immune System Diseases
Necrosis Antibodies	>3687 publications with C-JUN and Necrosis
Central Nervous System Diseases Antibodies	>2916 publications with C-JUN and Central Nervous System Diseases
Disease Models, Animal Antibodies	>2907 publications with C-JUN and Disease Models, Animal
Brain Diseases Antibodies	>2819 publications with C-JUN and Brain Diseases
Congenital Abnormalities Antibodies	>1994 publications with C-JUN and Congenital Abnormalities
Liver Diseases Antibodies	>1949 publications with C-JUN and Liver Diseases
Lung Diseases Antibodies	>1778 publications with C-JUN and Lung Diseases

Organs/Tissues associated with C-JUN elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6498 publications with C-JUN and Brain
Embryonic Tissue Antibodies	>1868 publications with C-JUN and Embryonic Tissue
Intestine Antibodies	>1159 publications with C-JUN and Intestine
Ovary Antibodies	>760 publications with C-JUN and Ovary
Adipose Tissue Antibodies	>596 publications with C-JUN and Adipose Tissue
Thymus Antibodies	>444 publications with C-JUN and Thymus
Uterus Antibodies	>422 publications with C-JUN and Uterus