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PFTK1 Antibody (N-Term P82) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9226326

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
PFTK1 (CDK14), Blocking Peptide
Full Product Name
PFTK1 Antibody (N-term P82) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
KIAA0834; PFTK1
Product Synonym Names
Cyclin-dependent kinase 14; Cell division protein kinase 14; Serine/threonine-protein kinase PFTAIRE-1; hPFTAIRE1; CDK14; KIAA0834; PFTK1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human PFTK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
PFTK1 peptide (MBS9226326) is used for blocking the activity of PFTK1 antibody (MBS9208851)
Molecular Weight
47,760 Da
OMIM
610679
Cellular Location
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note: Recruited to the cell membrane by CCNY
Tissue Location
Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.

Other Notes

Small volumes of CDK14 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK14 purchase

MBS9226326 is a blocking peptide targeting CDK14. Also known as PFTK1 Antibody (N-term P82) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK14. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cyclin-dependent kinase 14
NCBI Official Synonym Full Names
cyclin dependent kinase 14
NCBI Official Symbol
CDK14
NCBI Official Synonym Symbols
PFTK1; PFTAIRE1
UniProt Protein Name
Cyclin-dependent kinase 14
UniProt Synonym Protein Names
Cell division protein kinase 14; Serine/threonine-protein kinase PFTAIRE-1; hPFTAIRE1
UniProt Gene Name
CDK14
UniProt Synonym Gene Names
KIAA0834; PFTK1; hPFTAIRE1
UniProt Entry Name
CDK14_HUMAN
NCBI Protein Information
cyclin-dependent kinase 14

NCBI Summary for CDK14

PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]

UniProt Comments for CDK14

CDK14: a protein kinase of the CDK family. May play a role in meiosis as well as in neuron differentiation and/or function. Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, CMGC; Motility/polarity/chemotaxis; Kinase, protein; Cell cycle regulation; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; CDK family; CDK/TAIRE subfamily; TAIRE subfamily

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: cytoplasm; nucleus; plasma membrane

Molecular Function: cyclin binding; cyclin-dependent protein kinase activity; protein binding

Biological Process: G2/M transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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