Human ABCA8 cDNA Clone Expression Plasmid – Cat# MBS1274497

ABCA8 cDNA Clone – ATP-Binding Cassette, Sub-Family A (ABC1), Member 8 (Human)

Name: ABCA8 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274497
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274497

MBS1274497 is a cDNA clone targeting ABCA8. More details

$350 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABCA8, cDNA Clone

Full Product Name

ABCA8 cDNA Clone

Product Gene Name

ABCA8 cdna clone

Sequence

atgaggaaga gaaagatcag tgtgtgtcaa caaacttggg ccttattatg caagaacttt cttaaaaaat ggagaatgaa aagagagtcc ttaatggaat ggctgaattc attgctccta ctactttgtt tgtatatata tcctcatagt catcaagtaa atgatttttc ttcactgctt accatggacc tgggacgggt agatacattt aatgaatcca gattttctgt tgtatacaca cctgtcacca acacgaccca acagataatg aataaagtag cctctactcc cttcctggca ggtaaagagg tcttgggact gccagatgag gaaagtatta aagaattcac agcaaattat cctgaagaaa tagtaagagt cacctttact aatacatact catatcattt gaagttcttg ctaggacatg gaatgccagc aaagaaggag cacaaggacc atacagctca ttgttatgaa acaaatgaag atgtttactg tgaagtttca gtattttgga aggaaggttt tgtggctctt caagctgcca ttaatgctgc tattatagaa atcacaacaa atcactcagt gatggaggag ctgatgtcag ttactggaaa aaatatgaag atgcattcct tcattggtca atcaggagtt ataactgatt tgtacctttt ttcctgcatt atttcatttt cctcattcat ttactatgca tctgttaatg tcacaagaga gaggaaaagg atgaaggcct tgatgacaat gatgggtctt cgggattcag cgttctggtg a

Molecular Weight

183,677 Da

OMIM

612505

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ABCA8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCA8. It may not necessarily be applicable to this product.

NCBI GI #

28839742

NCBI GeneID

10351

NCBI Accession #

BC047765

UniProt Secondary Accession #

Q86WW0; A1L3U3; C9JQE6

UniProt Related Accession #

O94911

NCBI Official Full Name

Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 8, mRNA

NCBI Official Synonym Full Names

ATP binding cassette subfamily A member 8

NCBI Official Symbol

ABCA8

UniProt Protein Name

ATP-binding cassette sub-family A member 8

Protein Family

ABC transporter A family

UniProt Gene Name

ABCA8

UniProt Synonym Gene Names

KIAA0822

UniProt Entry Name

ABCA8_HUMAN

NCBI Protein Information

ATP-binding cassette sub-family A member 8

NCBI Summary for ABCA8

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt Comments for ABCA8

ABCA8: ATP-dependent lipophilic drug transporter. Belongs to the ABC transporter superfamily. ABCA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Mitochondrial; Transporter, ABC family; Transporter; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: mitochondrial inner membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; xenobiotic-transporting ATPase activity

Biological Process: lipid transport; transmembrane transport; transport

Research Articles on ABCA8

1. These data suggest a direct relationship between the levels of ABCA8 and the ectopic expression of alpha-syn and increased expression of p25alpha

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ABCA8 cdna clone

Products by Pathway	Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram
ABC-family Proteins Mediated Transport Pathway antibodies	ABC-family Proteins Mediated Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with ABCA8 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with ABCA8 and Neoplasms
Drug Toxicity Antibodies	>2 publications with ABCA8 and Drug Toxicity
Lung Neoplasms Antibodies	>1 publications with ABCA8 and Lung Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with ABCA8 and Ovarian Neoplasms
Brain Diseases Antibodies	>1 publications with ABCA8 and Brain Diseases
Nervous System Diseases Antibodies	>1 publications with ABCA8 and Nervous System Diseases

Organs/Tissues associated with ABCA8 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>10 publications with ABCA8 and Brain
Heart Antibodies	>5 publications with ABCA8 and Heart
Liver Antibodies	>4 publications with ABCA8 and Liver
Lung Antibodies	>2 publications with ABCA8 and Lung
Muscle Antibodies	>2 publications with ABCA8 and Muscle
Pancreas Antibodies	>1 publications with ABCA8 and Pancreas
Testis Antibodies	>1 publications with ABCA8 and Testis
Nerve Antibodies	>1 publications with ABCA8 and Nerve
Vascular Antibodies	>1 publications with ABCA8 and Vascular
Kidney Antibodies	>1 publications with ABCA8 and Kidney