Human ACTB cDNA Clone Expression Plasmid – Cat# MBS1268882

ACTB cDNA Clone – Actin, Beta (Human)

Name: ACTB cDNA Clone; Actin, Beta; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268882
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268882

MBS1268882 is a cDNA clone targeting ACTB. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACTB, cDNA Clone

Full Product Name

ACTB cDNA Clone

Product Gene Name

ACTB cdna clone

Sequence

atggatgatg atatcgccgc gctcgtcgtc gacaacggct ccggcatgtg caaggccggc ttcgcgggcg acgatgcccc ccgggccgtc ttcccctcca tcgtggggcg ccccaggcac cagggcgtga tggtgggcat gggtcagaag gattcctatg tgggcgacga ggcccagagc aagagaggca tcctcaccct gaagtacccc atcgagcacg gcatcgtcac caactgggac gacatggaga aaatctggca ccacaccttc tacaatgagc tgcgtgtgcc tcccgaggag caccccgtgc tgctgaccga ggcccccctg aaccccaagg ccaaccgcga gaagatgacc cagatcatgt ttgagacctt caacacccca gccatgtacg ttgctatcca ggctgtgcta tccctgtacg cctctggccg taccactggc atcgtgatgg actccggtga cggggtcacc cacactgtgc ccatctacga ggggtatgcc ctcccccatg ccatcctgcg tctggacctg gctggccggg acctgactga ctacctcatg aagatcctca ccgagcgcgg ctacagcttc accaccacgg ccgagcggga aatcgtgcgt gacattaagg agaagctgtg ctacgtcgcc ctggacttcg agcaagagat ggccacggct gcttccagct cctccctgga gaagagctac gagctgcctg acggccaggt catcaccatt ggcaatgagc ggttccgctg ccctgaggca ctcttccagc cttccttcct gggcatggag tcctgtggca tccacgaaac taccttcaac tccatcatga agtgtgacgt ggacatccgc aaagacctgt acgccaacac agtgctgtct ggcggcacca ccatgtaccc tggcattgcc gacaggatgc agaaggagat cactgccctg gcacccagca caatgaagat caagatcatt gctcctcctg agcgcaagta ctccgtgtgg atcggcggct ccatcctggc ctcgctgtcc accttccagc agatgtggat cagcaagcag gagtatgacg agtccggccc ctccatcgtc caccgcaaat gcttctag

Molecular Weight

41,737 Da

OMIM

102630

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ACTB cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACTB. It may not necessarily be applicable to this product.

NCBI GI #

16359157

NCBI GeneID

NCBI Accession #

BC016045

UniProt Secondary Accession #

P02570; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5

UniProt Related Accession #

P60709

NCBI Official Full Name

Homo sapiens actin, beta, mRNA

NCBI Official Synonym Full Names

actin beta

NCBI Official Symbol

ACTB

NCBI Official Synonym Symbols

BRWS1; PS1TP5BP1

UniProt Protein Name

Actin, cytoplasmic 1

UniProt Synonym Protein Names

Beta-actin

Protein Family

Actin

UniProt Gene Name

ACTB

UniProt Entry Name

ACTB_HUMAN

NCBI Protein Information

actin, cytoplasmic 1

NCBI Summary for ACTB

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]

UniProt Comments for ACTB

ACTB: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCET2. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cytoplasm; cytoskeleton; cytosol; extracellular space; focal adhesion; membrane; NuA4 histone acetyltransferase complex; nuclear chromatin; nucleoplasm; plasma membrane; protein complex; ribonucleoprotein complex

Molecular Function: identical protein binding; kinesin binding; nitric-oxide synthase binding; nucleosomal DNA binding; protein binding; structural constituent of cytoskeleton; Tat protein binding

Biological Process: ATP-dependent chromatin remodeling; cell motility; ephrin receptor signaling pathway; positive regulation of gene expression, epigenetic; retinal homeostasis; substantia nigra development; vascular endothelial growth factor receptor signaling pathway

Disease: Baraitser-winter Syndrome 1; Dystonia, Juvenile-onset

Research Articles on ACTB

1. crucial role of Glu270 in ADP-ribosylation of actin by Ia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ACTB cdna clone

Products by Pathway	Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Chaperonin-mediated Protein Folding Pathway antibodies	Chaperonin-mediated Protein Folding Pathway Diagram
Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies	Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram

Diseases associated with ACTB cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>79 publications with ACTB and Neoplasms
Carcinoma Antibodies	>39 publications with ACTB and Carcinoma
Liver Diseases Antibodies	>17 publications with ACTB and Liver Diseases
Disease Models, Animal Antibodies	>16 publications with ACTB and Disease Models, Animal
Breast Neoplasms Antibodies	>12 publications with ACTB and Breast Neoplasms
Lung Diseases Antibodies	>12 publications with ACTB and Lung Diseases
Brain Diseases Antibodies	>12 publications with ACTB and Brain Diseases
Kidney Diseases Antibodies	>11 publications with ACTB and Kidney Diseases
Liver Neoplasms Antibodies	>10 publications with ACTB and Liver Neoplasms
Necrosis Antibodies	>9 publications with ACTB and Necrosis

Organs/Tissues associated with ACTB cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>50 publications with ACTB and Blood
Brain Antibodies	>45 publications with ACTB and Brain
Liver Antibodies	>41 publications with ACTB and Liver
Muscle Antibodies	>37 publications with ACTB and Muscle
Kidney Antibodies	>24 publications with ACTB and Kidney
Lung Antibodies	>19 publications with ACTB and Lung
Heart Antibodies	>18 publications with ACTB and Heart
Embryonic Tissue Antibodies	>14 publications with ACTB and Embryonic Tissue
Bone Antibodies	>14 publications with ACTB and Bone
Connective Tissue Antibodies	>13 publications with ACTB and Connective Tissue