Human ACTL6A cDNA Clone Expression Plasmid – Cat# MBS1272792

ACTL6A cDNA Clone – Actin-Like 6a (Human)

Name: ACTL6A cDNA Clone; Actin-Like 6a; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272792
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272792

MBS1272792 is a cDNA clone targeting ACTL6A. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACTL6A, cDNA Clone

Full Product Name

ACTL6A cDNA Clone

Product Gene Name

ACTL6A cdna clone

Sequence

atgagcggcg gcgtgtacgg gggagatgaa gttggagccc ttgtttttga cattggatcc tatactgtga gagctggtta tgctggtgag gactgcccca aggtggattt tcctacagct attggtatgg tggtagaaag agatgacgga agcacattaa tggaaataga tggcgataaa ggcaaacaag gcggtcccac ctactacata gatactaatg ctctgcgtgt tccgagggag aatatggagg ccatttcacc tctaaaaaat gggatggttg aagactggga tagtttccaa gctattttgg atcataccta caaaatgcat gtcaaatcag aagccagtct ccatcctgtt ctcatgtcag aggcaccgtg gaatactaga gcaaagagag agaaactgac agagttaatg tttgaacact acaacatccc tgccttcttc ctttgcaaaa ctgcagtttt gacagcattt gctaatggtc gttctactgg gctgattttg gacagtggag ccactcatac cactgcaatt ccagtccacg atggctatgt ccttcaacaa ggcattgtga aatcccctct tgctggagac tttattacta tgcagtgcag agaactcttc caagaaatga atattgaatt ggttcctcca tatatgattg catcaaaaga agctgttcgt gaaggatctc cagcaaactg gaaaagaaaa gagaagttgc ctcaggttac gaggtcttgg cacaattata tgtgtaattg tgttatccag gattttcaag cttcggtact tcaagtgtca gattcaactt atgatgaaca agtggctgca cagatgccaa ctgttcatta tgaattcccc aatggctaca attgtgattt tggtgcagag cggctaaaga ttccagaagg attatttgac ccttccaatg taaaggggtt atcaggaaac acaatgttag gagtcagtca tgttgtcacc acaagtgttg ggatgtgtga tattgacatc agaccaggtc tctatggcag tgtaatagtg gcaggaggaa acacactaat acagagtttt actgacaggt tgaatagaga gctgtctcag aaaactcctc caagtatgcg gttgaaattg attgcaaata atacaacagt ggaacggagg tttagctcat ggattggcgg ctccattcta gcctctttgg gtacctttca acagatgtgg atttccaagc aagaatatga agaaggaggg aagcagtgtg tagaaagaaa atgcccttga

Molecular Weight

43,236 Da

OMIM

604958

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ACTL6A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACTL6A. It may not necessarily be applicable to this product.

NCBI GI #

22137781

NCBI GeneID

NCBI Accession #

BC036371

UniProt Secondary Accession #

Q8TAE5; Q9BVS8; Q9H0W6; B3KMN1; D3DNR9

UniProt Related Accession #

O96019

NCBI Official Full Name

Homo sapiens actin-like 6A, mRNA

NCBI Official Synonym Full Names

actin like 6A

NCBI Official Symbol

ACTL6A

NCBI Official Synonym Symbols

Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA

UniProt Protein Name

Actin-like protein 6A

UniProt Synonym Protein Names

53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K

Protein Family

Actin-like protein

UniProt Gene Name

ACTL6A

UniProt Synonym Gene Names

BAF53; BAF53A; INO80K; BAF53A

UniProt Entry Name

ACL6A_HUMAN

NCBI Protein Information

actin-like protein 6A

NCBI Summary for ACTL6A

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for ACTL6A

BAF53A: an actin-related protein involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of the helicase SMARCA4 and for association of the SMARCA4 containing remodelling complex BAF with chromatin/nuclear matrix. A component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of specific genes. Two alternatively spliced human isoforms have been described.

Chromosomal Location of Human Ortholog: 3q26.33

Cellular Component: NuA4 histone acetyltransferase complex; nuclear chromatin; nucleoplasm; nucleus; plasma membrane; protein complex; SWI/SNF complex

Molecular Function: chromatin binding; nucleosomal DNA binding; protein binding

Biological Process: ATP-dependent chromatin remodeling; chromatin remodeling; signal transduction

Research Articles on ACTL6A

1. ACTL6A protein expression predicts poor prognosis of hepatocellular carcinoma and metastasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ACTL6A cdna clone

Products by Pathway	Pathway Diagram
C-MYC Pathway antibodies	C-MYC Pathway Diagram
Gastric Cancer Network 1 Pathway antibodies	Gastric Cancer Network 1 Pathway Diagram
Prostate Cancer Pathway antibodies	Prostate Cancer Pathway Diagram
TNF-alpha/NF-kB Signaling Pathway antibodies	TNF-alpha/NF-kB Signaling Pathway Diagram
Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies	Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram

Diseases associated with ACTL6A cdna clone

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>1 publications with ACTL6A and Disease Models, Animal
Kidney Diseases Antibodies	>1 publications with ACTL6A and Kidney Diseases
Uterine Cervical Neoplasms Antibodies	>1 publications with ACTL6A and Uterine Cervical Neoplasms

Organs/Tissues associated with ACTL6A cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with ACTL6A and Brain
Kidney Antibodies	>2 publications with ACTL6A and Kidney
Embryonic Tissue Antibodies	>1 publications with ACTL6A and Embryonic Tissue