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ADNP cDNA Clone – Activity-Dependent Neuroprotector Homeobox (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274992

MBS1274992 is a cDNA clone targeting ADNP. More details

$1380 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ADNP, cDNA Clone
Full Product Name
ADNP cDNA Clone
Product Gene Name
ADNP cdna clone
Sequence
atgttccaac ttcctgtcaa caatcttggc agtttaagaa aagcccggaa aactgtgaaa aaaatactta gtgacattgg gttggaatac tgtaaagaac atatagaaga ttttaaacaa tttgaaccta atgactttta tttgaaaaac actacatggg aggatgtagg actgtgggac ccatcactta cgaaaaacca ggactatcgg acaaaacctt tctgctgcag cgcttgtcca tgttcctcaa aattcttctc tgcctacaaa agtcatttcc gcaatgtcca tagtgaagac tttgaaaata ggattctcct taattgcccc tactgtacct tcaatgcaga caaaaagact ttggaaacac acattaaaat atttcatgct ccgaacgcca gcgcaccaag tagcagcctc agcactttca aagataaaaa caaaaatgat ggccttaaac ctaagcaggc tgacagtgta gagcaagctg tttattactg taagaagtgc acttaccgag atcctcttta tgaaatagtt aggaagcaca tttacaggga acattttcag catgtggcag caccttacat agcaaaggca ggagaaaaat cactcaatgg ggcagtcccc ttaggctcga atgcccgaga agagagtagt attcactgca aacgatgcct tttcatgcca aagtcctatg aagctttggt acagcatgtc atcgaagacc atgaacgtat aggctatcag gtcactgcca tgattgggca cacaaatgta gtggttcccc gatccaaacc cttgatgcta attgctccca aacctcaaga caagaagagc atgggactcc caccaaggat cggttccctt gcttctggaa atgtccggtc tttaccatca cagcagatgg tgaatcgact ctcaatacca aagcctaact taaattctac aggagtcaac atgatgtcca gtgttcatct gcagcagaac aactatggag tcaaatctgt aggccagggt tacagtgttg gtcagtcaat gagactgggt ctaggtggca acgcaccagt ttccattcct caacaatctc agtctgtaaa gcagttactt ccaagtggaa acggaaggtc ttatgggctt gggtcagagc agaggtccca ggcaccagca agatactccc tgcagtctgc taatgcctct tctctctcat cgggccagtt aaagtctcct tccctctctc agtcacaggc atccagagtg ttaggtcagt ccagttccaa acctgctgca gctgccacag gccctccccc aggtaacact tcctcaactc aaaagtggaa aatatgtaca atctgtaatg agctttttcc tgaaaatgtc tatagtgtgc acttcgaaaa aggacataaa gctgagaaag tcccagcagt agccaactac attatgaaaa tacacaattt tactagcaaa tgcctctact gtaatcgcta tttacccaca gatactctgc tcaaccatat gttaattcat ggtctgtctt gtccatattg ccgttcaact ttcaatgatg tggaaaagat ggccgcacac atgcggatgg ttcacattga tgaagagatg ggacctaaaa cagattctac tttgagtttt gatttgacat tgcagcaggg tagtcacact aacatccatc tcctggtaac tacatacaat ctgagggatg ccccagctga atctgttgct taccatgccc aaaataatcc tccagttcct ccaaagccac agccaaaggt tcaggaaaag gcagatatcc ctgtaaaaag ttcacctcaa gctgcagtgc cctataaaaa agatgttggg aaaacccttt gtcctctttg cttttcaatc ctaaaaggac ccatatctga tgcacttgca catcacttac gagagaggca ccaagttatt cagacggttc atccagttga gaaaaagctc acctacaaat gtatccattg ccttggtgtg tataccagca acatgaccgc ctcaactatc actctgcatc tagttcactg caggggcgtt ggaaagaccc aaaatggcca ggataagaca aatgcaccct ctcggcttaa tcagtctcca agtctggcac ctgtgaagcg cacttacgag caaatggaat ttcccttact gaaaaaacga aagttagatg atgatagtga ttcacccagc ttctttgaag agaagcctga agagcctgtt gttttagctt tagaccccaa gggtcatgaa gatgattcct atgaagccag gaaaagcttt ctaacaaagt atttcaacaa acagccctat cccaccagga gagaaattga gaagctagca gccagtttat ggttatggaa gagtgacatc gcttcccatt ttagtaacaa aaggaagaag tgtgtccgtg attgtgaaaa gtacaagcct ggcgtgttgc tggggtttaa catgaaagaa ttaaataaag tcaagcatga gatggatttt gacgctgagt ggctatttga aaatcatgat gagaaggatt ccagagtcaa tgctagtaag actgctgaca aaaagctcaa ccttgggaag gaagatgaca gttcctcaga cagttttgaa aatttggaag aagaatccaa tgaaagtggt agcccttttg accctgtttt tgaagttgaa cctaaaatct ctaacgataa cccagaggaa catgtactga aggtaattcc tgaggatgct tcagaatctg aggagaagct agaccaaaaa gaggatggtt caaaatacga aactattcat ttgactgagg aaccaaccaa actaatgcac aatgcatctg atagtgaggt tgaccaagac gatgttgttg agtggaaaga cggtgcttct ccatctgaga gtgggcctgg atcccaacaa gtgtcagact ttgaggacaa tacctgcgaa atgaaaccag gaacctggtc tgacgagtct tcccaaagcg aagatgcaag gagcagtaag ccagctgcca aaaaaaaggc taccatgcaa ggtgacagag agcagttgaa atggaagaat agttcctatg gaaaagttga agggttttgg tctaaggacc agtcacagtg gaagaatgca tctgagaatg atgagcgctt atctaacccc cagattgagt ggcagaatag cacaattgac agtgaggatg gggaacagtt tgacaacatg actgatggag tagctgagcc catgcatggc agcttagccg gagttaaact gagcagccaa caggcctaa
Molecular Weight
123,563 Da
OMIM
611386
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ADNP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADNP. It may not necessarily be applicable to this product.

NCBI GI #
50370284
NCBI GeneID
23394
NCBI Accession #
BC075794
UniProt Secondary Accession #
O94881; Q5BKU2; Q9UG34; E1P5Y2
UniProt Related Accession #
Q9H2P0
NCBI Official Full Name
Homo sapiens activity-dependent neuroprotector homeobox, mRNA
NCBI Official Synonym Full Names
activity dependent neuroprotector homeobox
NCBI Official Symbol
ADNP
NCBI Official Synonym Symbols
ADNP1; HVDAS; MRD28
UniProt Protein Name
Activity-dependent neuroprotector homeobox protein
UniProt Synonym Protein Names
Activity-dependent neuroprotective protein
Protein Family
Activity-dependent neuroprotector homeobox protein
UniProt Gene Name
ADNP
UniProt Synonym Gene Names
ADNP1; KIAA0784
UniProt Entry Name
ADNP_HUMAN
NCBI Protein Information
activity-dependent neuroprotector homeobox protein

NCBI Summary for ADNP

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for ADNP

ADNP: Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.

Protein type: C2H2-type zinc finger protein; DNA-binding; Apoptosis

Chromosomal Location of Human Ortholog: 20q13.13

Molecular Function: protein binding

Disease: Mental Retardation, Autosomal Dominant 28
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Research Articles on ADNP

1. ADNP expression was increased in male hippocampus samples compared to female samples.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ADNP cdna clone

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >26 publications with ADNP and Brain Diseases
 Drug Toxicity Antibodies  >22 publications with ADNP and Drug Toxicity
 Death Antibodies  >19 publications with ADNP and Death
 Neurodegenerative Diseases Antibodies  >15 publications with ADNP and Neurodegenerative Diseases
 Disease Models, Animal Antibodies  >15 publications with ADNP and Disease Models, Animal
 Brain Injuries Antibodies  >10 publications with ADNP and Brain Injuries
 Inflammation Antibodies  >4 publications with ADNP and Inflammation
 Seizures Antibodies  >4 publications with ADNP and Seizures
 Nerve Degeneration Antibodies  >4 publications with ADNP and Nerve Degeneration
 Poisoning Antibodies  >3 publications with ADNP and Poisoning

Organs/Tissues associated with ADNP cdna clone

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >73 publications with ADNP and Nerve
 Brain Antibodies  >65 publications with ADNP and Brain
 Embryonic Tissue Antibodies  >13 publications with ADNP and Embryonic Tissue
 Blood Antibodies  >9 publications with ADNP and Blood
 Eye Antibodies  >6 publications with ADNP and Eye
 Placenta Antibodies  >2 publications with ADNP and Placenta
 Kidney Antibodies  >2 publications with ADNP and Kidney
 Uterus Antibodies  >2 publications with ADNP and Uterus
 Ganglia Antibodies  >2 publications with ADNP and Ganglia
 Heart Antibodies  >1 publications with ADNP and Heart
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