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ADRM1 cDNA Clone – Adhesion Regulating Molecule 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270382

MBS1270382 is a cDNA clone targeting ADRM1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADRM1, cDNA Clone
Full Product Name
ADRM1 cDNA Clone
Product Gene Name
ADRM1 cdna clone
Sequence
atgacgacct caggcgcgct ctttccaagc ctggtgccag gctctcgggg cgcctccaac aagtacttgg tggagtttcg ggcgggaaag atgtccctga aggggaccac cgtgactccg gataagcgga aagggctggt gtacattcag cagacggacg actcgcttat tcacttctgc tggaaggaca ggacgtccgg gaacgtggaa gacgacttga tcatcttccc tgacgactgt gagttcaagc gggtgccgca gtgccccagc gggagggtct acgtgctgaa gttcaaggca gggtccaagc ggcttttctt ctggatgcag gaacccaaga cagaccagga tgaggagcat tgccggaaag tcaacgagta tctgaacaac cccccgatgc ctggggcact gggggccagc ggaagcagcg gccacgaact ctctgcgcta ggcggtgagg gtggcctgca gagcctgctg ggaaacatga gccacagcca gctcatgcag ctcatcggac cagccggcct cggaggactg ggtgggctgg gggccctgac tggacctggc ctggccagtt tactggggag cagtgggcct ccagggagca gctcctcctc cagctcccgg agccagtcgg cagcggtcac cccgtcatcc accacctctt ccacccgtgc caccccagcc ccttctgctc cagcagctgc ctcagcaact agcccgagcc ccgcgcccag ttccgggaat ggagccagca cagcagccag cccgacccag cccatccagc tgagcgacct ccagagcatc ctggccacga tgaacgtacc agccgggcca gcaggcggcc agcaagtgga cctggccagt gtgctgacgc cggagataat ggctcccatc ctcgccaacg cggatgtcca ggagcgcctg cttccctact tgccatctgg ggagtcgctg ccgcagaccg cggatgagat ccagaatacc ctgacctcgc cccagttcca gcaggccctg ggcatgttca gcgcagcctt ggcctcgggg cagctgggcc ccctcatgtg ccagttcggt ctgcctgcag aggctgtgga ggccgccaac aagggcgatg tggaagcgtt tgccaaagcc atgcagaaca acgccaagcc cgagcagaaa gagggcgaca cgaaggacaa gaaggacgaa gaggaggaca tgagcctgga ctga
Molecular Weight
42,153 Da
OMIM
610650
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ADRM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADRM1. It may not necessarily be applicable to this product.

NCBI GI #
33878567
NCBI GeneID
11047
NCBI Accession #
BC017245
UniProt Secondary Accession #
Q96FJ7; Q9H1P2; A0PKB1
UniProt Related Accession #
Q16186
NCBI Official Full Name
Homo sapiens adhesion regulating molecule 1, mRNA
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Official Symbol
ADRM1
NCBI Official Synonym Symbols
ARM1; ARM-1; GP110
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Synonym Protein Names
110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog
Protein Family
Proteasomal ubiquitin receptor
UniProt Gene Name
ADRM1
UniProt Synonym Gene Names
GP110; Gp110; ARM-1; hRpn13
UniProt Entry Name
ADRM1_HUMAN
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1

NCBI Summary for ADRM1

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for ADRM1

ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family.

Protein type: Proteasome complex; Cell development/differentiation

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cytoplasm; integral to plasma membrane; membrane; nucleoplasm; plasma membrane; proteasome complex

Molecular Function: protease binding; protein binding

Biological Process: proteasome assembly; RNA elongation from RNA polymerase II promoter
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Research Articles on ADRM1

1. the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ADRM1 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >11 publications with ADRM1 and Neoplasms
 Carcinoma Antibodies  >6 publications with ADRM1 and Carcinoma
 Adenocarcinoma Antibodies  >3 publications with ADRM1 and Adenocarcinoma
 Liver Neoplasms Antibodies  >2 publications with ADRM1 and Liver Neoplasms
 Breast Neoplasms Antibodies  >2 publications with ADRM1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with ADRM1 and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >1 publications with ADRM1 and Carcinoma, Hepatocellular
 Nervous System Diseases Antibodies  >1 publications with ADRM1 and Nervous System Diseases
 Liver Diseases Antibodies  >1 publications with ADRM1 and Liver Diseases
 Brain Diseases Antibodies  >1 publications with ADRM1 and Brain Diseases

Organs/Tissues associated with ADRM1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with ADRM1 and Kidney
 Liver Antibodies  >2 publications with ADRM1 and Liver
 Ovary Antibodies  >2 publications with ADRM1 and Ovary
 Bone Antibodies  >2 publications with ADRM1 and Bone
 Lymph Antibodies  >2 publications with ADRM1 and Lymph
 Lymph Node Antibodies  >2 publications with ADRM1 and Lymph Node
 Blood Antibodies  >1 publications with ADRM1 and Blood
 Prostate Antibodies  >1 publications with ADRM1 and Prostate
 Pancreas Antibodies  >1 publications with ADRM1 and Pancreas
 Embryonic Tissue Antibodies  >1 publications with ADRM1 and Embryonic Tissue
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