Human AGFG1 cDNA Clone Expression Plasmid – Cat# MBS1268161

AGFG1 cDNA Clone – Arfgap with Fg Repeats 1 (Human)

Name: AGFG1 cDNA Clone; Arfgap with Fg Repeats 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268161
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268161

MBS1268161 is a cDNA clone targeting AGFG1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AGFG1, cDNA Clone

Full Product Name

AGFG1 cDNA Clone

Product Gene Name

AGFG1 cdna clone

Sequence

atggcggcca gcgcgaagcg gaagcaggag gagaagcacc tgaagatgct gcgggacatg accggcctcc cgcacaaccg aaagtgcttc gactgcgacc agcgcggccc cacctacgtt aacatgacgg tcggctcctt cgtgtgtacc tcctgctccg gcagcctgcg aggattaaat ccaccacaca gggtgaaatc tatctccatg acaacattca cacaacagga aattgaattc ttacaaaaac atggaaatga agtctgtaag cagatttggc taggattatt tgatgataga tcttcagcaa ttccagactt cagggatcca caaaaagtga aagagtttct acaagaaaag tatgaaaaga aaagatggta tgtcccgcca gaacaagcca aagtcgtggc atcagttcat gcatctattt cagggtcctc tgccagtagc acaagcagca cacctgaggt caaaccactg aaatctcttt taggggattc tgcaccaaca ctgcacttaa ataagggcac acctagtcag tccccagttg taggtcgttc tcaagggcag cagcaggaga agaagcaatt tgacctttta agtgatctcg gctcagacat ctttgctgct ccagctcctc agtcaacagc tacagccaat tttgctaact ttgcacattt caacagtcat gcagctcaga attctgcaaa tgcagatttt gcaaactttg atgcatttgg acagtctagt ggttcgagta attttggagg tttccccaca gcaagtcact ctccttttca gccccaaact acaggtggaa gtgctgcatc agtaaatgct aattttgctc attttgataa cttccccaaa tcctccagtg ctgattttgg aaccttcaat acttcccaga gtcatcaaac agcatcagct gttagtaaag tttcaacgaa caaagctggt ttacagactg cagacaaata tgcagcactt gctaatttag acaatatctt cagtgccggg caaggtggtg atcagggaag tggctttggg accacaggta aagctcctgt tggttctgtg gtttcagttc ccagtcagtc aagtgcatct tcagacaagt atgcagctct ggcagaacta gacagcgttt tcagttctgc agccacctcc agtaatgcgt atacttccac aagtaatgct agcagcaatg tttttggaac agtgccagtg gttgcttctg cacagacaca gcctgcttca tcaagtgtgc ctgctccatt tggagctacg ccttccacaa atccatttgt tgctgctgct ggtccttctg tggcatcttc tacaaaccca tttcagacca atgccagagg agcaacagcg gcaacctttg gcactgcatc catgagcatg cccacgggat tcggcactcc tgctccctac agtcttccca ccagctttag tggcagcttt cagcagcctg cctttccagc ccaagcagct ttccctcaac agacagcttt ttctcaacag cccaatggtg caggttttgc agcatttgga caaacaaagc cagtagtaac cccttttggt caagttgcag ctgctggagt atctagtaat ccttttatga ctggtgcacc aacaggacaa tttccaacag gaagctcatc aaccaatcct ttcttatag

Molecular Weight

60,767 Da

OMIM

600862

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of AGFG1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AGFG1. It may not necessarily be applicable to this product.

NCBI GI #

34192113

NCBI GeneID

3267

NCBI Accession #

BC030592

UniProt Secondary Accession #

Q15277; Q4VAS0; Q4VAS1; Q4VAS3; Q53QT8; Q53R11; B3KUL1; E9PHX7

UniProt Related Accession #

P52594

NCBI Official Full Name

Homo sapiens ArfGAP with FG repeats 1, mRNA

NCBI Official Synonym Full Names

ArfGAP with FG repeats 1

NCBI Official Symbol

AGFG1

NCBI Official Synonym Symbols

HRB; RAB; RIP

UniProt Protein Name

Arf-GAP domain and FG repeat-containing protein 1

UniProt Synonym Protein Names

HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein

Protein Family

Arf-GAP domain and FG repeat-containing protein

UniProt Gene Name

AGFG1

UniProt Synonym Gene Names

HRB; RAB; RIP

UniProt Entry Name

AGFG1_HUMAN

NCBI Protein Information

arf-GAP domain and FG repeat-containing protein 1

NCBI Summary for AGFG1

The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

UniProt Comments for AGFG1

RIP: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. Interacts with EPS15R and EPS15. Interacts with FCHO1. Ubiquitously expressed. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Nuclear export

Chromosomal Location of Human Ortholog: 2q36.3

Cellular Component: intracellular membrane-bound organelle; nuclear pore

Molecular Function: protein binding; RNA binding

Biological Process: mRNA export from nucleus

Research Articles on AGFG1

1. HRB knock-down affected CD4 downregulation induced by Nef but not by HIV-1 Vpu.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with AGFG1 cdna clone

Products by Pathway	Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram

Diseases associated with AGFG1 cdna clone

Disease Name	Pubmed Publications
Necrosis Antibodies	>49 publications with AGFG1 and Necrosis
Neoplasms Antibodies	>21 publications with AGFG1 and Neoplasms
Inflammation Antibodies	>9 publications with AGFG1 and Inflammation
Cell Transformation, Neoplastic Antibodies	>4 publications with AGFG1 and Cell Transformation, Neoplastic
Skin Diseases Antibodies	>3 publications with AGFG1 and Skin Diseases
Liver Diseases Antibodies	>3 publications with AGFG1 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with AGFG1 and Liver Neoplasms
Drug Toxicity Antibodies	>1 publications with AGFG1 and Drug Toxicity
Brain Diseases Antibodies	>1 publications with AGFG1 and Brain Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with AGFG1 and Carcinoma, Hepatocellular

Organs/Tissues associated with AGFG1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>12 publications with AGFG1 and Blood
Lung Antibodies	>7 publications with AGFG1 and Lung
Liver Antibodies	>4 publications with AGFG1 and Liver
Heart Antibodies	>3 publications with AGFG1 and Heart
Brain Antibodies	>3 publications with AGFG1 and Brain
Kidney Antibodies	>2 publications with AGFG1 and Kidney
Vascular Antibodies	>2 publications with AGFG1 and Vascular
Pancreas Antibodies	>2 publications with AGFG1 and Pancreas
Intestine Antibodies	>2 publications with AGFG1 and Intestine
Thyroid Antibodies	>1 publications with AGFG1 and Thyroid