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AGXT2L2 cDNA Clone – Alanine-Glyoxylate Aminotransferase 2-Like 2 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276699

MBS1276699 is a cDNA clone targeting AGXT2L2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AGXT2L2, cDNA Clone
Full Product Name
AGXT2L2 cDNA Clone
Product Gene Name
AGXT2L2 cdna clone
Sequence
atggccgcag accagcgccc gaaggccgac acgctggccc tgaggcaacg gctcatcagc tcttcctgca gactcttttt tcccgaggat cctgttaaga ttgtccgggc ccaagggcag tacatgtacg atgaacaggg ggcagaatac atcgattgca tcagcaatgt ggcgcacgtt gggcactgcc accctctcgt ggtccaagca gcacatgagc agaaccaggt gctcaacacc aacagccggt acctgcatga caacatcgtg gactatgcgc agaggctgtc agagaccctg ccggagcagc tctgtgtgtt ctatttcctg aattctgggt cagaagccaa tgacctggcc ctgaggctgg ctcgccacta cacgggacac caggacgtgg tggtattaga tcatgcgtat cacggccacc tgagctccct gattgacatc agtccctaca agttccgcaa cctggatggc cagaaggagt gggtccacgt ggcacctctc ccagacacct accggggccc ctaccgggag gaccacccca acccagctat ggcctatgcc aacgaggtga aacgtgtggt cagcagtgca caggagaagg gcaggaagat tgcagccttc ttcgctgagt ctctgcccag tgtgggaggg cagatcattc cccctgctgg ctacttctcc caagtggcag agcacatccg caaggccgga ggggtctttg ttgcagatga gatccaggtt ggctttggcc gggtaggcaa gcacttctgg gccttccagc tccagggaaa agacttcgtc cctgacatcg tcaccatggg caagtccatt ggcaacggcc accctgttgc ctgcgtggcc gcaacccagc ctgtggcgag ggcatttgaa gccaccggcg ttgagtactt caacacgttt gggggcagcc cagtgtcctg cgctgtgggg ctggccgtcc tgaatgtctt ggagaaggag cagctccagg atcatgccac cagtgtaggc agcttcctga tgcagctcct cgggcagcaa aaaatcaaac atcccatcgt cggggatgtc aggggtgttg ggctcttcat tggtgtggat ctgatcaaag atgaggccac aaggacacca gcaactgaag aggctgccta cttggtatca aggctgaagg agaactacgt tttgctgagc actgatggcc ctgggaggaa catcctgaag tttaagcccc caatgtgctt cagcctggac aatgcacggc aggtggtggc aaagctggat gccattctga ctgacatgga agagaaggtg agaagttgtg aaacgctgag gctccagccc taa
Molecular Weight
18,857 Da
OMIM
614683
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of AGXT2L2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AGXT2L2. It may not necessarily be applicable to this product.

NCBI GI #
22902220
NCBI GeneID
85007
NCBI Accession #
BC037567
UniProt Secondary Accession #
Q8WYS6; Q96HW8; A8K7P6; B3KN36; D3DWP9
UniProt Related Accession #
Q8IUZ5
NCBI Official Full Name
Homo sapiens alanine-glyoxylate aminotransferase 2-like 2, mRNA
NCBI Official Synonym Full Names
5-phosphohydroxy-L-lysine phospho-lyase
NCBI Official Symbol
PHYKPL
NCBI Official Synonym Symbols
PHLU; AGXT2L2
UniProt Protein Name
5-phosphohydroxy-L-lysine phospho-lyase
UniProt Synonym Protein Names
Alanine--glyoxylate aminotransferase 2-like 2
UniProt Gene Name
PHYKPL
UniProt Synonym Gene Names
AGXT2L2
UniProt Entry Name
AT2L2_HUMAN
NCBI Protein Information
5-phosphohydroxy-L-lysine phospho-lyase

NCBI Summary for AGXT2L2

This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
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UniProt Comments for AGXT2L2

AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 4.2.3.134

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: mitochondrial matrix

Molecular Function: identical protein binding; lyase activity; protein binding; pyridoxal phosphate binding

Biological Process: collagen catabolic process; lysine catabolic process

Disease: Phosphohydroxylysinuria
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Research Articles on AGXT2L2

1. Phosphohydroxylysinuria is due to mutations in the AGXT2L2 gene and the resulting lack of activity of phosphohydroxylysine phospholyase in vivo.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with AGXT2L2 cdna clone

 Products by Pathway  Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies  Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
 Lysine Catabolism Pathway antibodies  Lysine Catabolism Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
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