Human ATP6AP2 cDNA Clone Expression Plasmid – Cat# MBS1272504

ATP6AP2 cDNA Clone – Atpase, H+ Transporting, Lysosomal Accessory Protein 2 (Human)

Name: ATP6AP2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272504
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272504

MBS1272504 is a cDNA clone targeting ATP6AP2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATP6AP2, cDNA Clone

Full Product Name

ATP6AP2 cDNA Clone

Product Gene Name

ATP6AP2 cdna clone

Sequence

ATGGCTGTGT TTGTCGTGCT CCTGGCGTTG GTGGCGGGTG TTTTGGGGAA CGAGTTTAGT ATATTAAAAT CACCAGGGTC TGTTGTTTTC CGAAATGGAA ATTGGCCTAT ACCAGGAGAG CGGATCCCAG ACGTGGCTGC ATTGTCCATG GGCTTCTCTG TGAAAGAAGA CCTTTCTTGG CCAGGACTCG CAGTGGGTAA CCTGTTTCAT CGTCCTCGGG CTACCGTCAT GGTGATGGTG AAGGGAGTGA ACAAACTGGC TCTACCCCCA GGCAGTGTCA TTTCGTACCC TTTGGAGAAT GCAGTTCCTT TTAGTCTTGA CAGTGTTGCA AATTCCATTC ACTCCTTATT TTCTGAGGAA ACTCCTGTTG TTTTGCAGTT GGCTCCCAGT GAGGAAAGAG TGTATATGGT AGGGAAGGCA AACTCAGTGT TTGAAGACCT TTCAGTCACC TTGCGCCAGC TCCGTAATCG CCTGTTTCAA GAAAACTCTG TTCTCAGTTC ACTCCCCCTC AATTCTCTGA GTAGGAACAA TGAAGTTGAC CTGCTCTTTC TTTCTGAACT GCAAGTGCTA CATGATATTT CAAGCTTGCT GTCTCGTCAT AAGCATCTAG CCAAGGATCA TTCTCCTGAT TTATATTCAC TGGAGCTGGC AGGTTTGGAT GAAATTGGGA AGCGTTATGG GGAAGACTCT GAACAATTCA GAGATGCTTC TAAGATCCTT GTTGACGCTC TGCAAAAGTT TGCAGATGAC ATGTACAGTC TTTATGGTGG GAATGCAGTG GTAGAGTTAG TCACTGTCAA GTCATTTGAC ACCTCCCTCA TTAGGAAGAC AAGGACTATC CTTGAGGCAA AACAAGCGAA GAACCCAGCA AGTCCCTATA ACCTTGCATA TAAGTATAAT TTTGAATATT CCGTGGTTTT CAACATGGTA CTTTGGATAA TGATCGCCTT GGCCTTGGCT GTGATTATCA CCTCTTACAA TATTTGGAAC ATGGATCCTG GATATGATAG CATCATTTAT AGGATGACAA ACCAGAAGAT TCGAATGGAT TGA

Molecular Weight

35,612 Da

OMIM

300423

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ATP6AP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP6AP2. It may not necessarily be applicable to this product.

NCBI GI #

54038755

NCBI GeneID

10159

NCBI Accession #

BC084541

UniProt Secondary Accession #

Q5QTQ7; Q6T7F5; Q8NBP3; Q8NG15; Q96FV6; Q96LB5; Q9H2P8; Q9UG89; B7Z9I3

UniProt Related Accession #

O75787

NCBI Official Full Name

Homo sapiens ATPase, H+ transporting, lysosomal accessory protein 2, mRNA

NCBI Official Synonym Full Names

ATPase H+ transporting accessory protein 2

NCBI Official Symbol

ATP6AP2

NCBI Official Synonym Symbols

PRR; M8-9; MRXE; RENR; XMRE; XPDS; HT028; MRXSH; ELDF10; ATP6IP2; MSTP009; APT6M8-9; ATP6M8-9

UniProt Protein Name

Renin receptor

UniProt Synonym Protein Names

ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10; N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit

Protein Family

Renin receptor

UniProt Gene Name

ATP6AP2

UniProt Synonym Gene Names

ATP6IP2; CAPER; ELDF10; ATP6M8-9; V-ATPase M8.9 subunit

UniProt Entry Name

RENR_HUMAN

NCBI Protein Information

renin receptor

NCBI Summary for ATP6AP2

This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]

UniProt Comments for ATP6AP2

ATP6AP2: Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS). Defects in ATP6AP2 are a cause of mental retardation X- linked with epilepsy (MRXE). MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp11.4

Disease: Mental Retardation, X-linked, Syndromic, Hedera Type; Parkinsonism With Spasticity, X-linked

Research Articles on ATP6AP2

1. Study identifies a renin-angiotensin system-independent function for the (P)RR in the regulation of LDL metabolism by controlling the levels of SORT1 and LDL receptor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ATP6AP2 cdna clone

Products by Pathway	Pathway Diagram
ACE Inhibitor Pathway antibodies	ACE Inhibitor Pathway Diagram
Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies	Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Wnt Signaling Network Pathway antibodies	Wnt Signaling Network Pathway Diagram

Diseases associated with ATP6AP2 cdna clone

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>27 publications with ATP6AP2 and Cardiovascular Diseases
Hypertension Antibodies	>23 publications with ATP6AP2 and Hypertension
Kidney Diseases Antibodies	>9 publications with ATP6AP2 and Kidney Diseases
Fibrosis Antibodies	>6 publications with ATP6AP2 and Fibrosis
Heart Diseases Antibodies	>5 publications with ATP6AP2 and Heart Diseases
Inflammation Antibodies	>4 publications with ATP6AP2 and Inflammation
Neoplasms Antibodies	>3 publications with ATP6AP2 and Neoplasms
Proteinuria Antibodies	>3 publications with ATP6AP2 and Proteinuria
Hypertrophy Antibodies	>3 publications with ATP6AP2 and Hypertrophy
Atherosclerosis Antibodies	>3 publications with ATP6AP2 and Atherosclerosis

Organs/Tissues associated with ATP6AP2 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>23 publications with ATP6AP2 and Kidney
Blood Antibodies	>18 publications with ATP6AP2 and Blood
Vascular Antibodies	>12 publications with ATP6AP2 and Vascular
Heart Antibodies	>11 publications with ATP6AP2 and Heart
Muscle Antibodies	>10 publications with ATP6AP2 and Muscle
Placenta Antibodies	>6 publications with ATP6AP2 and Placenta
Brain Antibodies	>6 publications with ATP6AP2 and Brain
Embryonic Tissue Antibodies	>4 publications with ATP6AP2 and Embryonic Tissue
Eye Antibodies	>4 publications with ATP6AP2 and Eye
Uterus Antibodies	>2 publications with ATP6AP2 and Uterus