Human B4GALT3 cDNA Clone Expression Plasmid – Cat# MBS1278056

B4GALT3 cDNA Clone – UDP-Gal:betaglcnac Beta 1,4- Galactosyltransferase, Polypeptide 3 (Human)

Name: B4GALT3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278056
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278056

MBS1278056 is a cDNA clone targeting B4GALT3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

B4GALT3, cDNA Clone

Full Product Name

B4GALT3 cDNA Clone

Product Gene Name

B4GALT3 cdna clone

Sequence

atgttgcgga ggctgctgga gcggccttgc acgctggccc tgcttgtggg ctcccagctg gctgtcatga tgtacctgtc actggggggc ttccgaagtc tcagtgccct atttggccga gatcagggac cgacatttga ctattctcac cctcgtgatg tctacagtaa cctcagtcac ctgcctgggg ccccaggggg tcctccagct cctcaaggtc tgccctactg tccagaacga tctcctctct tagtgggtcc tgtgtcagtg tcctttagcc cagtgccatc actggcagag attgtggagc ggaatccccg ggtagaacca gggggccggt accgccctgc aggttgtgag ccccgctccc gaacagccat cattgtgcct catcgtgccc gggagcacca cctgcgcctg ctgctctacc acctgcaccc cttcttgcag cgccagcagc ttgcttatgg catctatgtc atccaccagg ctggaaatgg aacatttaac agggcaaaac tgttgaatgt tggggtgcga gaggccctgc gtgatgaaga gtgggactgc ctgttcttgc acgatgtgga cctcttgcca gaaaatgacc acaatctgta tgtgtgtgac ccccggggac cccgccatgt tgccgttgct atgaacaagt ttggatacag cctcccgtac ccccagtact tcggaggagt ctcagcactt actcctgacc agtacctgaa gatgaatggc ttccccaatg aatactgggg ctggggtggt gaggatgacg acattgctac cagggtgcgc ctggctggga tgaagatctc tcggcccccc acatctgtag gacactataa gatggtgaag caccgaggag ataagggcaa tgaggaaaat ccccacagat ttgacctcct ggtccgtacc cagaattcct ggacgcaaga tgggatgaac tcactgacat accagttgct ggctcgagag ctggggcctc tttataccaa catcacagca gacattggga ctgaccctcg gggtcctcgg gctccttctg ggccacgtta cccacctggt tcctcccaag ccttccgtca agagatgctg caacgccggc ccccagccag gcctgggcct ctatctactg ccaaccacac agccctccga ggttcacact ga

Molecular Weight

15,654 Da

OMIM

604014

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of B4GALT3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for B4GALT3. It may not necessarily be applicable to this product.

NCBI GI #

12653026

NCBI GeneID

8703

NCBI Accession #

BC000276

UniProt Secondary Accession #

O60910; Q9BPZ4; Q9H8T2; D3DVG3

UniProt Related Accession #

O60512

NCBI Official Full Name

Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3, mRNA

NCBI Official Synonym Full Names

beta-1,4-galactosyltransferase 3

NCBI Official Symbol

B4GALT3

NCBI Official Synonym Symbols

beta4Gal-T3

UniProt Protein Name

Beta-1,4-galactosyltransferase 3

UniProt Synonym Protein Names

UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3Including the following 3 domains:N-acetyllactosamine synthase (EC:2.4.1.90)Alternative name(s):Nal synthase

Protein Family

Beta-1,4-galactosyltransferase

UniProt Gene Name

B4GALT3

UniProt Synonym Gene Names

Beta-1,4-GalTase 3; Beta4Gal-T3; b4Gal-T3

UniProt Entry Name

B4GT3_HUMAN

NCBI Protein Information

beta-1,4-galactosyltransferase 3

NCBI Summary for B4GALT3

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for B4GALT3

B4GALT3: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Belongs to the glycosyltransferase 7 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Glycan Metabolism - N-glycan biosynthesis; EC 2.4.1.38; Transferase; Membrane protein, integral; Glycan Metabolism - keratan sulfate biosynthesis; EC 2.4.1.90; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane

Molecular Function: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; galactosyltransferase activity

Biological Process: keratan sulfate biosynthetic process

Research Articles on B4GALT3

1. our findings evidenced that B4GALT3 upregulated by miR-27a contributes to the tumorigenic activities by b1-integrin pathway and might provide potential biomarkers for cervical cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with B4GALT3 cdna clone

Products by Pathway	Pathway Diagram
Asparagine N-linked Glycosylation Pathway antibodies	Asparagine N-linked Glycosylation Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies	Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies	Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies	Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
Glycosphingolipid Biosynthesis, Neolacto-series, LacCer => NLc4Cer Pathway antibodies	Glycosphingolipid Biosynthesis, Neolacto-series, LacCer => NLc4Cer Pathway Diagram
Glycosphingolipid Biosynthesis, Neolacto-series, LacCer => NLc4Cer Pathway antibodies	Glycosphingolipid Biosynthesis, Neolacto-series, LacCer => NLc4Cer Pathway Diagram
Keratan Sulfate Biosynthesis Pathway antibodies	Keratan Sulfate Biosynthesis Pathway Diagram

Diseases associated with B4GALT3 cdna clone

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>1 publications with B4GALT3 and Immune System Diseases

Organs/Tissues associated with B4GALT3 cdna clone

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with B4GALT3 and Bone
Brain Antibodies	>1 publications with B4GALT3 and Brain