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BEND3 cDNA Clone – BEN Domain Containing 3 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274013

MBS1274013 is a cDNA clone targeting BEND3. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BEND3, cDNA Clone
Full Product Name
BEND3 cDNA Clone
Product Gene Name
BEND3 cdna clone
Sequence
ATGAACTCAA CTGAATTCAC CGAAGATGTA GAAGAAGTTC TAAAAAGTAT CACTGTGAAA GTGGAGACAG AGGCTGAAGA TGCTGCTCTG GACTGCTCCG TGAATTCCAG GACTTCTGAG AAGCACTCTG TGGACAGCGT CCTCACTGCC CTGCAGGACT CCAGCAAACG AAAGCAGCTG GTCAGCGATG GCCTGCTAGA CTCTGTCCCC GGCGTGAAGA GGAGGCGGCT GATCCCCGAG GCTCTCCTAG CAGGCATGCG GAACCGTGAG AACAGCTCGC CCTGCCAAGG CAATGGTGAG CAGGCCGGCA GGGGCAGGAG CCTGGGCAAT GTGTGGCCTG GAGAGGAGGA GCCCTGCAAC GATGCCACCA CCCCTTCCTA CAAGAAGCCT CTGTATGGCA TCTCGCACAA GATCATGGAG AAGAAGAATC CTCCCTCGGG GGACCTGCTA AACGTGTACG AGCTCTTTGA GAAGGCAAAC GCCAGCAACA GCCCCTCGTC ACTGCGGCTC CTGAATGAGC CACAGAAGCG GGACTGTGGC AGCACCGGGG CAGGCACTGA CAACGACCCC AACATCTACT TCCTGATCCA GAAGATGTTC TACATGCTGA ACACCCTCAC GTCCAACATG TCCCAGCTGC ACAGCAAGGT GGACCTGCTC TCCCTTGAGG TGAGCCGCAT CAAGAAGCAG GTGAGCCCCA CTGAGATGGT GGCCAAATTC CAGCCGCCCC CTGAGTACCA GCTCACAGCC GCAGAGCTCA AGCAGATCGT GGACCAGAGC CTGTCAGGGG GGGACCTGGC CTGCCGCTTG CTGGTGCAGC TCTTCCCCGA GCTCTTCAGC GACGTGGACT TCTCCCGGGG CTGCAGTGCC TGTGGCTTTG CGGCCAAGCG CAAGCTGGAG TCGCTGCACC TGCAGCTCAT CCGCAACTAT GTGGAGGTCT ACTACCCCTC GGTGAAGGAC ACGGCTGTGT GGCAGGCCGA GTGCCTGCCC CAGCTGAACG ACTTCTTCAG CCGCTTCTGG GCCCAGCGGG AAATGGAGGA CAGCCAGCCC AGCGGCCAGG TCGCCAGCTT CTTTGAGGCA GAGCAGGTGG ACCCCGGCCA CTTCCTGGAC AACAAAGACC AGGAGGAGGC CCTGTCTCTT GACCGGAGCA GCACCATCGC CTCAGACCAC GTGGTGGACA CGCAGGACCT CACTGAGTTC CTGGACGAAG CCTCCTCACC AGGCGAGTTT GCCGTCTTCC TCCTCCACCG GCTCTTCCCC GAGCTCTTCG ACCACCGCAA GCTGGGTGAA CAGTACAGCT GCTACGGGGA CGGTGGAAAG CAGGAGCTGG ACCCGCAGCG GCTGCAGATC ATCCGCAACT ACACGGAGAT CTACTTCCCT GACATGCAGG AGGAGGAGGC CTGGCTGCAG CAGTGTGCCC AGCGCATCAA CGACGAGCTC GAGGGCCTGG GGCTGGACGC GGGCAGTGAA GGCGACCCCC CGCGTGATGA CTGCTACGAC TCCTCCAGTC TGCCCGACGA CATCTCAGTG GTCAAGGTGG AGGACAGCTT CGAGGGCGAG CGGCCGGGTC GCCGCTCCAA GAAGATCTGG CTGGTGCCCA TCGACTTCGA CAAGTTAGAG ATCCCCCAGC CTGACTTCGA GGTGCCCGGT GCCGACTGCC TGCTCAGCAA GGAGCAGCTA CGCAGCATCT ACGAGAGCAG CCTGTCCATC GGCAACTTCG CCTCGCGCCT GCTGGTGCAC CTGTTCCCCG AGCTCTTCAC GCACGAGAAC CTGCGCAAGC AGTACAGCTG CAGCGGCTCC CTGGGCAAGA AGCAGCTGGA CCCCTCCCGC ATCAAGCTCA TCCGCCACTA CGTGCAGCTG CTCTACCCAC GCGCCAAAAA CGACCGCGTC TGGACCCTGG AGTTCGTGGG CAAACTGGAT GAGCGCTGCC GGCGCCGGGA CACGGAGCAA AGGCGCTCCT ACCAGCAGCA GCGCAAGGTC CACGTGCCGG GCCCTGAGTG CAGAGACTTG ACCAGCTATG CAATCAACCC CGAGAGGTTC CGGGAGGAGT TTGAGGGGCC CCCACTGCCC CCCGAGAGGA GCAGCAAGGA CTTTTGCAAG ATCCCCTTGG ACGAGCTGGT GGTCCCCTCG CCTGACTTCC CGGTGCCTTC TCCCTACCTG CTGTCTGACA AGGAGGTGCG TGAGATCGTG CAGCAGAGCC TCTCCGTGGG CAACTTTGCC GCCCGGCTCC TCGTCCGCCT GTTTCCCGAA CTCTTCACCG CCGAGAACCT CCGGCTGCAG TACAACCATT CCGGGGCTTG CAACAAGAAG CAACTGGACC CCACGCGGCT GCGGCTCATC CGCCACTACG TGGAAGCCGT CTACCCGGTG GAGAAGATGG AGGAGGTGTG GCACTACGAA TGTATCCCCA GCATCGATGA GAGGTGCCGC CGCCCCAACA GGAAAAAATG CGACATCCTC AAGAAAGCAA AGAAAGTGGA GAAGTGA
Molecular Weight
94,475 Da
OMIM
616374
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of BEND3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BEND3. It may not necessarily be applicable to this product.

NCBI GI #
124297092
NCBI GeneID
57673
NCBI Accession #
BC131628
UniProt Secondary Accession #
Q9HCL9; A2RRH2
UniProt Related Accession #
Q5T5X7
NCBI Official Full Name
Homo sapiens BEN domain containing 3, mRNA
NCBI Official Synonym Full Names
BEN domain containing 3
NCBI Official Symbol
BEND3
NCBI Official Synonym Symbols
KIAA1553
UniProt Protein Name
BEN domain-containing protein 3
Protein Family
BEN domain-containing protein
UniProt Gene Name
BEND3
UniProt Synonym Gene Names
KIAA1553
UniProt Entry Name
BEND3_HUMAN
NCBI Protein Information
BEN domain-containing protein 3

UniProt Comments for BEND3

BEND3: Involved in transcription repression. {ECO:0000269|PubMed:21914818}. Interacts with HDAC2 and HDAC3, but not HDAC1. Interacts with SALL4. {ECO:0000269|PubMed:21914818}

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: nuclear heterochromatin; nucleolus

Molecular Function: protein binding; rDNA binding

Biological Process: chromatin silencing at rDNA; DNA methylation; negative regulation of transcription from RNA polymerase II promoter
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Research Articles on BEND3

1. propose that there is a link between binding of BEND3 to the CALR rs138452745 C-allele and removal of NFI binding site from this nucleotide, and the evolution of human-specific higher brain functions

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with BEND3 cdna clone

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >4 publications with BEND3 and Brain Diseases
 Nervous System Diseases Antibodies  >3 publications with BEND3 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with BEND3 and Disease Models, Animal
 Liver Failure Antibodies  >1 publications with BEND3 and Liver Failure
 Neurodegenerative Diseases Antibodies  >1 publications with BEND3 and Neurodegenerative Diseases
 Brain Edema Antibodies  >1 publications with BEND3 and Brain Edema
 Liver Diseases Antibodies  >1 publications with BEND3 and Liver Diseases

Organs/Tissues associated with BEND3 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >29 publications with BEND3 and Brain
 Bone Antibodies  >3 publications with BEND3 and Bone
 Liver Antibodies  >3 publications with BEND3 and Liver
 Spinal Cord Antibodies  >1 publications with BEND3 and Spinal Cord
 Lung Antibodies  >1 publications with BEND3 and Lung
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