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BIK cDNA Clone – BCL2-Interacting Killer (Apoptosis-Inducing) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273482

MBS1273482 is a cDNA clone targeting BIK. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BIK, cDNA Clone
Full Product Name
BIK cDNA Clone
Product Gene Name
Sequence
atgtctgaag taagacccct ctccagagac atcttgatgg agaccctcct gtatgagcag ctcctggaac ccccgaccat ggaggttctt ggcatgactg actctgaaga ggacctggac cctatggagg acttcgattc tttggaatgc atggagggca gtgacgcatt ggccctgcgg ctggcctgca tcggggacga gatggacgtg agcctcaggg ccccgcgcct ggcccagctc tccgaggtgg ccatgcacag cctgggtctg gctttcatct acgaccagac tgaggacatc agggatgttc ttagaagttt catggacggt ttcaccacac ttaaggagaa cataatgagg ttctggagat ccccgaaccc cgggtcctgg gtgtcctgcg aacaggtgct gctggcgctg ctgctgctgc tggcgctgct gctgccgctg ctcagcgggg gcctgcacct gctgctcaag tga
Molecular Weight
18,016 Da
OMIM
603392
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of BIK cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BIK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens BCL2-interacting killer (apoptosis-inducing), mRNA
NCBI Official Synonym Full Names
BCL2 interacting killer
NCBI Official Symbol
BIK
NCBI Official Synonym Symbols
BP4; NBK; BIP1
UniProt Protein Name
Bcl-2-interacting killer
UniProt Synonym Protein Names
Apoptosis inducer NBK; BIP1; BP4
UniProt Gene Name
BIK
UniProt Synonym Gene Names
NBK
UniProt Entry Name
BIK_HUMAN
NCBI Protein Information
bcl-2-interacting killer

NCBI Summary for BIK

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
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UniProt Comments for BIK

BIK: accelerates programmed cell death. Binding to the apoptosis repressors Bcl-xL, Bcl-2, or BHRF1 (the Epstein-Barr virus homolog of Bcl-2) suppresses its death-promoting activity. Contains 1 Bcl-2 homology 3 (BH3) domain. Does not interact with Bax.

Protein type: Apoptosis; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 22q13.31

Molecular Function: protein binding

Biological Process: apoptosis; male gonad development; positive regulation of protein homooligomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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