Human C9 cDNA Clone Expression Plasmid – Cat# MBS1278424

C9 cDNA Clone – Complement Component 9 (Human)

Name: C9 cDNA Clone; Complement Component 9; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278424
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278424

MBS1278424 is a cDNA clone targeting C9. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

C9, cDNA Clone

Full Product Name

C9 cDNA Clone

Product Gene Name

C9 cdna clone

Sequence

atgtcagcct gccggagctt tgcagttgca atctgcattt tagaaataag catcctcaca gcacagtaca cgaccagtta tgacccagag ctaacagaaa gcagtggctc tgcatcacac atagactgca gaatgagccc ctggagtgaa tggtcacaat gcgatccttg tctcagacaa atgtttcgtt caagaagcat tgaggtcttt ggacaattta atgggaaaag atgcaccgac gctgtgggag acagacgaca gtgtgtgccc acagagccct gtgaggatgc tgaggatgac tgcggaaatg actttcaatg cagtacaggc agatgcataa agatgcgact tcggtgtaat ggtgacaatg actgcggaga cttttcagat gaggatgatt gtgaaagtga gccccgtccc ccctgcagag acagagtggt agaagagtct gagctggcac gaacagcagg ctatgggatc aacattttag ggatggatcc cctaagcaca ccttttgaca atgagttcta caatggactc tgtaaccggg atcgggatgg aaacactctg acatactacc gaagaccttg gaacgtggct tctttgatct atgaaaccaa aggcgagaaa aatttcagaa ccgaacatta cgaagaacaa attgaagcat ttaaaagtat catccaagag aagacatcaa attttaatgc agctatatct ctaaaattta cacccactga aacaaataaa gctgaacaat gttgtgagga aacagcctcc tcaatttctt tacatggcaa gggtagtttt cggttttcat attccaaaaa tgaaacttac caactatttt tgtcatattc ttcaaagaag gaaaaaatgt ttctgcatgt gaaaggagaa attcatctgg gaagatttgt aatgagaaat cgcgatgttg tgctcacaac aacttttgtg gatgatataa aagctttgcc aactacctat gaaaagggag aatattttgc ctttttggaa acctatggaa ctcactacag tagctctggg tctctaggag gactctatga actaatatat gttttggata aagcttccat gaagcggaaa ggtgttgaac taaaagacat aaagagatgc cttgggtatc atctggatgt atctctggct ttctctgaaa tctctgttgg agctgaattt aataaagatg attgtgtaaa gaggggagag ggtagagctg taaacatcac cagtgaaaac ctcatagatg atgttgtttc actcataaga ggtggaacca gaaaatatgc atttgaactg aaagaaaagc ttctccgagg aaccgtgatt gatgtgactg actttgtcaa ctgggcctct tccataaatg atgctcctgt tctcattagt caaaaactgt ctcctatata taatctggtt ccagtgaaaa tgaaaaatgc acacctaaag aaacaaaact tggaaagagc cattgaagac tatatcaatg aatttagtgt aagaaaatgc cacacatgcc aaaatggagg tacagtgatt ctaatggatg gaaagtgttt gtgtgcctgc ccattcaaat ttgagggaat tgcctgtgaa atcagtaaac aaaaaatttc tgaaggattg ccagccctag agttccccaa tgaaaaatag

Molecular Weight

63,173 Da

OMIM

120940

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of C9 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C9. It may not necessarily be applicable to this product.

NCBI GI #

18088820

NCBI GeneID

735

NCBI Accession #

BC020721

UniProt Related Accession #

P02748

NCBI Official Full Name

Homo sapiens complement component 9, mRNA

NCBI Official Synonym Full Names

complement C9

NCBI Official Symbol

NCBI Official Synonym Symbols

C9D; ARMD15

UniProt Protein Name

Complement component C9

Protein Family

Complement component

UniProt Gene Name

UniProt Entry Name

CO9_HUMAN

NCBI Protein Information

complement component C9

NCBI Summary for C9

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]

UniProt Comments for C9

C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Extracellular matrix; Membrane protein, multi-pass; Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: cytoplasm; extracellular region; integral to plasma membrane; plasma membrane

Biological Process: hemolysis by symbiont of host red blood cells; regulation of complement activation

Disease: Complement Component 9 Deficiency; Macular Degeneration, Age-related, 15

Research Articles on C9

1. Serum-expressed apolipoprotein B-100 protein, C9 Complement, and gelsolin can be used for differential diagnosis of Barrertts esophagus and adenocarcinoma of esophagus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with C9 cdna clone

Products by Pathway	Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Complement Activation, Classical Pathway antibodies	Complement Activation, Classical Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Prion Diseases Pathway antibodies	Prion Diseases Pathway Diagram

Diseases associated with C9 cdna clone

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>127 publications with C9 and Kidney Diseases
Death Antibodies	>109 publications with C9 and Death
Drug Toxicity Antibodies	>84 publications with C9 and Drug Toxicity
Necrosis Antibodies	>82 publications with C9 and Necrosis
Brain Diseases Antibodies	>71 publications with C9 and Brain Diseases
Fatty Liver Antibodies	>54 publications with C9 and Fatty Liver
Liver Diseases Antibodies	>47 publications with C9 and Liver Diseases
Weight Loss Antibodies	>34 publications with C9 and Weight Loss
Immunologic Deficiency Syndromes Antibodies	>28 publications with C9 and Immunologic Deficiency Syndromes
Liver Neoplasms Antibodies	>21 publications with C9 and Liver Neoplasms

Organs/Tissues associated with C9 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>233 publications with C9 and Liver
Muscle Antibodies	>167 publications with C9 and Muscle
Kidney Antibodies	>166 publications with C9 and Kidney
Placenta Antibodies	>12 publications with C9 and Placenta
Pancreas Antibodies	>12 publications with C9 and Pancreas
Uncharacterized Tissue Antibodies	>1 publications with C9 and Uncharacterized Tissue