Human CACNG3 cDNA Clone Expression Plasmid – Cat# MBS1270761

CACNG3 cDNA Clone – Calcium Channel, Voltage-Dependent, Gamma Subunit 3 (Human)

Name: CACNG3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270761
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270761

MBS1270761 is a cDNA clone targeting CACNG3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CACNG3, cDNA Clone

Full Product Name

CACNG3 cDNA Clone

Product Gene Name

CACNG3 cdna clone

Sequence

atgaggatgt gtgacagagg tatccagatg ttgatcacca ctgtaggagc ctttgccgct tttagtttaa tgaccattgc agtgggcacg gactactggt tatattccag aggtgtgtgc aggactaaat ctacaagtga taatgaaacc agcaggaaga atgaagaagt aatgacccat tcggggctgt ggaggacctg ctgcctagaa ggggctttcc gaggcgtgtg caagaaaatc gatcacttcc ctgaagatgc tgactacgaa caggacacag ccgaatatct cctgcgagct gtgagggcct ccagtgtctt ccccatcctc agtgtcacgc tgctgttctt cggcgggctc tgcgtggcag ccagtgagtt ccaccgcagc agacacaacg tcattctcag cgcgggcatc ttttttgtct ctgcagggtt aagcaacatc attggcatca tagtttatat atcagccaac gccggagacc ccgggcagcg tgactccaaa aaaagttact cctatggttg gtccttttat ttcggagcct tctctttcat catcgcagaa attgtaggag tggttgccgt gcacatctat attgaaaaac atcagcagtt acgagccaaa tcccactcgg agttcctgaa gaaatctact tttgcccgcc tcccacccta caggtatcga ttccggaggc ggtcaagttc tcgctccacc gagcccagat cccgagacct gtcccccatc agcaaaggct tccacaccat cccttccact gacatctcga tgttcaccct ctcccgggac ccctcaaaga tcaccatggg gaccctcctc aactccgacc gggaccacgc ttttctacag ttccacaatt ccacacccaa agagttcaaa gagtcactgc ataataatcc ggccaacagg cgcaccacgc ccgtctga

Molecular Weight

35,549 Da

OMIM

606403

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CACNG3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CACNG3. It may not necessarily be applicable to this product.

NCBI GI #

25058363

NCBI GeneID

10368

NCBI Accession #

BC040005

UniProt Related Accession #

O60359

NCBI Official Full Name

Homo sapiens calcium channel, voltage-dependent, gamma subunit 3, mRNA

NCBI Official Synonym Full Names

calcium voltage-gated channel auxiliary subunit gamma 3

NCBI Official Symbol

CACNG3

UniProt Protein Name

Voltage-dependent calcium channel gamma-3 subunit

UniProt Synonym Protein Names

Neuronal voltage-gated calcium channel gamma-3 subunit; Transmembrane AMPAR regulatory protein gamma-3; TARP gamma-3

Protein Family

Voltage-dependent calcium channel

UniProt Gene Name

CACNG3

UniProt Synonym Gene Names

TARP gamma-3

UniProt Entry Name

CCG3_HUMAN

NCBI Protein Information

voltage-dependent calcium channel gamma-3 subunit

NCBI Summary for CACNG3

The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010]

UniProt Comments for CACNG3

CACNG3: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

Protein type: Channel, calcium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p12.1

Cellular Component: plasma membrane

Molecular Function: channel regulator activity; voltage-gated calcium channel activity

Biological Process: transmission of nerve impulse

Research Articles on CACNG3

1. These results suggest that CACNG3 is the best candidate for an age-related macular degeneration risk gene within the 16p12 linkage peak.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CACNG3 cdna clone

Products by Pathway	Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram
Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram
Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway antibodies	Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway Diagram
Hypertrophic Cardiomyopathy (HCM) Pathway antibodies	Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
Hypertrophic Cardiomyopathy (HCM) Pathway antibodies	Hypertrophic Cardiomyopathy (HCM) Pathway Diagram

Diseases associated with CACNG3 cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>4 publications with CACNG3 and Nervous System Diseases
Seizures Antibodies	>3 publications with CACNG3 and Seizures
Brain Diseases Antibodies	>3 publications with CACNG3 and Brain Diseases
Movement Disorders Antibodies	>1 publications with CACNG3 and Movement Disorders
Disease Models, Animal Antibodies	>1 publications with CACNG3 and Disease Models, Animal

Organs/Tissues associated with CACNG3 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with CACNG3 and Brain