Human CAPNS1 cDNA Clone Expression Plasmid – Cat# MBS1270742

CAPNS1 cDNA Clone – Calpain, Small Subunit 1 (Human)

Name: CAPNS1 cDNA Clone; Calpain, Small Subunit 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270742
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270742

MBS1270742 is a cDNA clone targeting CAPNS1. More details

$405 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CAPNS1, cDNA Clone

Full Product Name

CAPNS1 cDNA Clone

Product Gene Name

CAPNS1 cdna clone

Sequence

atgttcctgg ttaactcgtt cttgaagggc ggcggcggcg gcggcggggg aggcgggggc ctgggtgggg gcctgggaaa tgtgcttgga ggcctgatca gcggggccgg gggcggcggc ggcggcggcg gcggcggcgg cggtggtgga ggcggcggtg gcggtggaac ggccatgcgc atcctaggcg gagtcatcag cgccatcagc gaggcggctg cgcagtacaa cccggagccc ccgcccccac gcacacatta ctccaacatt gaggccaacg agagtgagga ggtccggcag ttccggagac tctttgccca gctggctgga gatgacatgg aggtcagcgc cacagaactc atgaacattc tcaataaggt tgtgacacga caccctgatc tgaagactga tggttttggc attgacacat gtcgcagcat ggtggccgtg atggatagcg acaccacagg caagctgggc tttgaggaat tcaagtactt gtggaacaac atcaaaaggt ggcaggccat atacaaacag ttcgacactg accgatcagg gaccatttgc agtagtgaac tcccaggtgc ctttgaggca gcagggttcc acctgaatga gcatctctat aacatgatca tccgacgcta ctcagatgaa agtgggaaca tggattttga caacttcatc agctgcttgg tcaggctgga cgccatgttc cgtgccttca aatctcttga caaagatggc actggacaaa tccaggtgaa catccaggag gtaaggaccc ccatattggg gtatgggtgc ctgggaggac cccacccctc agcccttcat accagctctg agctgcagtc cccttcctcc tattttgcca gccgtccctg ggtgagggca aaggggctgg tgctcttggg gttccctgtc ctcactctcc accctcctct ccccagtggc tgcagctga

Molecular Weight

28,316 Da

OMIM

114170

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CAPNS1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAPNS1. It may not necessarily be applicable to this product.

NCBI GI #

33873870

NCBI GeneID

826

NCBI Accession #

BC011903

UniProt Secondary Accession #

Q8WTX3; Q96EW0; A8K0P1

UniProt Related Accession #

P04632

NCBI Official Full Name

Homo sapiens calpain, small subunit 1, mRNA

NCBI Official Synonym Full Names

calpain small subunit 1

NCBI Official Symbol

CAPNS1

NCBI Official Synonym Symbols

CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4

UniProt Protein Name

Calpain small subunit 1

UniProt Synonym Protein Names

Calcium-activated neutral proteinase small subunit; CANP small subunit; Calcium-dependent protease small subunit; CDPS; Calcium-dependent protease small subunit 1; Calpain regulatory subunit

Protein Family

Calpain

UniProt Gene Name

CAPNS1

UniProt Synonym Gene Names

CAPN4; CAPNS; CSS1; CANP small subunit; CDPS

UniProt Entry Name

CPNS1_HUMAN

NCBI Protein Information

calpain small subunit 1

NCBI Summary for CAPNS1

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

UniProt Comments for CAPNS1

CAPNS1: Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Protein type: Protease; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: cytosol; membrane

Molecular Function: calcium-dependent cysteine-type endopeptidase activity; protein binding

Biological Process: extracellular matrix disassembly; positive regulation of cell proliferation

Research Articles on CAPNS1

1. High levels of Capn4 expression were associated with lymph node metastasis and large tumor size in non-small cell lung cancer patients.Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CAPNS1 cdna clone

Products by Pathway	Pathway Diagram
Apoptosis Modulation And Signaling Pathway antibodies	Apoptosis Modulation And Signaling Pathway Diagram
Integrin-mediated Cell Adhesion Pathway antibodies	Integrin-mediated Cell Adhesion Pathway Diagram

Diseases associated with CAPNS1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with CAPNS1 and Neoplasms
Carcinoma Antibodies	>5 publications with CAPNS1 and Carcinoma
Death Antibodies	>4 publications with CAPNS1 and Death
Carcinoma, Hepatocellular Antibodies	>4 publications with CAPNS1 and Carcinoma, Hepatocellular
Adenocarcinoma Antibodies	>3 publications with CAPNS1 and Adenocarcinoma
Liver Neoplasms Antibodies	>3 publications with CAPNS1 and Liver Neoplasms
Liver Diseases Antibodies	>3 publications with CAPNS1 and Liver Diseases
Fibrosis Antibodies	>2 publications with CAPNS1 and Fibrosis
Heart Diseases Antibodies	>2 publications with CAPNS1 and Heart Diseases
Cardiovascular Diseases Antibodies	>2 publications with CAPNS1 and Cardiovascular Diseases