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CD1B cDNA Clone – Cd1b Molecule (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273790

MBS1273790 is a cDNA clone targeting CD1B. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD1B, cDNA Clone
Full Product Name
CD1B cDNA Clone
Product Gene Name
CD1B cdna clone
Sequence
atgctgctgc tgccatttca actgttagct gttctctttc ctggtggtaa cagtgaacat gccttccagg ggccgacctc ctttcatgtt atccagacct cgtcctttac caatagtacc tgggcacaaa ctcaaggctc aggctggttg gatgatttgc agattcatgg ctgggatagc gactcaggca ctgccatatt cctgaagcct tggtctaaag gtaactttag tgataaggag gttgctgagt tagaggagat attccgagtc tacatctttg gattcgctcg agaagtacaa gactttgccg gtgatttcca gatgaaatac ccctttgaga tccagggcat agcaggctgt gagctacatt ctggaggtgc catagtaagc ttcctgaggg gagctctagg aggattggat ttcctgagtg tcaagaatgc ttcatgtgtg ccttccccag aaggtggcag cagggcacag aaattctgtg cactaatcat acaatatcaa ggtatcatgg aaactgtgag aattctcctc tatgaaacct gcccccgata tctcttgggc gtcctcaatg caggaaaagc agatctgcaa agacaagtga agcctgaggc ctggctgtcc agtggcccca gtcctggacc tggccgtctg cagcttgtgt gccatgtctc aggattctac ccaaagcccg tgtgggtgat gtggatgcgg ggtgagcagg agcagcaggg cactcagcta ggggacatcc tgcccaatgc taactggaca tggtatctcc gagcaaccct ggatgtggca gatggggagg cggctggcct gtcctgtcgg gtgaagcaca gcagtttaga gggccaggac atcatcctct actggagaaa ccccacctcc attggctcaa ttgttttggc aataatagtg ccttccttgc tccttttgct atgccttgca ttatggtata tgaggcgccg gtcatatcag aatatcccat ga
Molecular Weight
30,740 Da
OMIM
188360
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CD1B cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD1B. It may not necessarily be applicable to this product.

NCBI GI #
47481187
NCBI GeneID
910
NCBI Accession #
BC069481
UniProt Secondary Accession #
Q5TDK9; Q5TDL0; Q9UMM2
UniProt Related Accession #
P29016
NCBI Official Full Name
Homo sapiens CD1b molecule, mRNA
NCBI Official Synonym Full Names
CD1b molecule
NCBI Official Symbol
CD1B
NCBI Official Synonym Symbols
R1; CD1; CD1A
UniProt Protein Name
T-cell surface glycoprotein CD1b
UniProt Synonym Protein Names
CD_antigen: CD1b
Protein Family
T-cell surface glycoprotein
UniProt Gene Name
CD1B
UniProt Entry Name
CD1B_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD1b

NCBI Summary for CD1B

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD1B

CD1B: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: cell surface; plasma membrane

Molecular Function: beta-2-microglobulin binding; endogenous lipid antigen binding; exogenous lipid antigen binding; protein binding

Biological Process: antigen processing and presentation, exogenous lipid antigen via MHC class Ib; regulation of immune response
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Research Articles on CD1B

1. the development of polyvalent complexes of CD1b proteins and carbohydrate backbones (dextramers) and their use in identifying CD1b autoreactive T cells from human donors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CD1B cdna clone

 Products by Pathway  Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with CD1B cdna clone

 Disease Name  Pubmed Publications
 Leukemia Antibodies  >16 publications with CD1B and Leukemia
 Lymphoma Antibodies  >11 publications with CD1B and Lymphoma
 Necrosis Antibodies  >9 publications with CD1B and Necrosis
 Dermatitis Antibodies  >8 publications with CD1B and Dermatitis
 Lymphoma, Non-Hodgkin Antibodies  >5 publications with CD1B and Lymphoma, Non-Hodgkin
 Neurologic Manifestations Antibodies  >4 publications with CD1B and Neurologic Manifestations
 Hematologic Diseases Antibodies  >4 publications with CD1B and Hematologic Diseases
 Lung Diseases, Interstitial Antibodies  >4 publications with CD1B and Lung Diseases, Interstitial
 Bone Marrow Diseases Antibodies  >3 publications with CD1B and Bone Marrow Diseases
 Encephalomyelitis Antibodies  >3 publications with CD1B and Encephalomyelitis

Organs/Tissues associated with CD1B cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >197 publications with CD1B and Blood
 Thymus Antibodies  >20 publications with CD1B and Thymus
 Heart Antibodies  >5 publications with CD1B and Heart
 Kidney Antibodies  >5 publications with CD1B and Kidney
 Lung Antibodies  >4 publications with CD1B and Lung
 Eye Antibodies  >1 publications with CD1B and Eye
 Pharynx Antibodies  >1 publications with CD1B and Pharynx
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