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CDKN2AIP cDNA Clone – CDKN2A Interacting Protein (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268786

MBS1268786 is a cDNA clone targeting CDKN2AIP. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDKN2AIP, cDNA Clone
Full Product Name
CDKN2AIP cDNA Clone
Product Gene Name
CDKN2AIP cdna clone
Sequence
atggcgcagg aggtgtcgga gtacctgagc cagaacccgc gggtggcagc ctgggtggag gcgctgcgct gcgacggcga gactgacaaa cactggcgcc accgccggga ttttttgctt cgcaacgccg gggacctggc ccccgctggc ggcgctgcct ccgctagcac ggatgaagct gccgacgccg agagcgggac ccgaaaccgg cagctgcagc agctcatctc cttttccatg gcctgggcga accacgtctt cctcgggtgc cgataccctc aaaaagttat ggataaaata cttagtatgg ctgaaggcat caaagtgaca gatgctccaa cctatacaac aagagatgaa ctggttgcca aggtgaagaa aagagggata tcgagtagca atgaaggggt agaagagcca tccaaaaaac gagttataga aggaaaaaac agttctgcag ttgagcaaga tcacgcaaaa acctctgcca agacagaacg tgcatcagct cagcaggaaa acagttcaac gtgtataggg tcggccatca aatcagagag tgggaactca gctcggagct ctggcatctc cagtcagaat agctctacaa gtgatggaga tcgatctgtt tccagccaaa gcagcagcag cgtttcctct caggtaacaa cggcaggatc tgggaaagct tctgaagcag aagctccaga taaacacggt tcatcatttg tttccttgct gaaatccagt gtgaatagtc acatgaccca atccactgat tctagacaac aaagtggatc acctaaaaag agtgctttgg aaggctcttc agcctcagct tctcaaagca gctcagagat cgaggtgccc ttgttgggct cctcaggaag ctcagaggta gaattgccac tattgtcttc caaacctagt tcagagacag cttcaagtgg gttaacttcc aaaactagtt cagaggcaag tgtttcatca tcagttgcta aaaacagttc ctcatcaggc acatccttac tgactcccaa gagcagctct tcaacaaata catcgctgct aacttccaag agcacttccc aggtagctgc atcactacta gcttccaaga gcagctccca gaccagtgga tctctggttt ccaaaagcac ttccttagca agtgtgtccc agttggcttc taagagtagt tctcagacta gcacctcaca gttgccttct aaaagtactt cacagtcaag tgagagttct gtcaaattct cttgcaagtt aaccaatgaa gatgtgaaac agaagcaacc ttttttcaat agactatata aaacggtggc atggaagttg gtagctgttg gtggctttag tcccaatgtg aatcatggag agctcctaaa tgcagctatt gaggctctga aagcaacact ggatgtattt tttgtcccac taaaagaatt ggcagatctg cctcaaaata agagctctca agaaagtatt gtttgtgaat tgaggtgcaa gtctgtgtat ttgggcactg gctgtggaaa aagcaaagaa aatgcaaaag cagttgcatc aagagaagca ttgaagttat ttctcaagaa aaaggtggtg gtaaaaatat gtaaaaggaa atacagaggc agtgaaatag aagatctagt actccttgat gaagaatcga ggcctgtaaa cttacctcca gcactaaaac atcctcaaga attactataa
Molecular Weight
61,125 Da
OMIM
615914
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CDKN2AIP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDKN2AIP. It may not necessarily be applicable to this product.

NCBI GI #
18490354
NCBI GeneID
55602
NCBI Accession #
BC022270
UniProt Secondary Accession #
Q8TBM5; Q9NYH0
UniProt Related Accession #
Q9NXV6
NCBI Official Full Name
Homo sapiens CDKN2A interacting protein, mRNA
NCBI Official Synonym Full Names
CDKN2A interacting protein
NCBI Official Symbol
CDKN2AIP
NCBI Official Synonym Symbols
CARF
UniProt Protein Name
CDKN2A-interacting protein
UniProt Synonym Protein Names
Collaborator of ARF
Protein Family
CDKN2A-interacting protein
UniProt Gene Name
CDKN2AIP
UniProt Synonym Gene Names
CARF
UniProt Entry Name
CARF_HUMAN
NCBI Protein Information
CDKN2A-interacting protein

NCBI Summary for CDKN2AIP

The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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UniProt Comments for CDKN2AIP

CDKN2AIP: co-localizes and interacts with p14ARF in the nucleolus. Co-regulated with ARF and cooperates with it in activating p53.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: granular component; nucleolus; nucleoplasm

Molecular Function: p53 binding; protein binding

Biological Process: negative regulation of cell growth; positive regulation of cell growth; positive regulation of signal transduction; regulation of protein stability; response to DNA damage stimulus
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Research Articles on CDKN2AIP

1. CARF promotes carcinogenesis in p53-deficient cells by repressing p21WAF1 and promoting cell cycle progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CDKN2AIP cdna clone

 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >1 publications with CDKN2AIP and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >1 publications with CDKN2AIP and Breast Neoplasms
 Drug Toxicity Antibodies  >1 publications with CDKN2AIP and Drug Toxicity
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