Human CHRM1 cDNA Clone Expression Plasmid – Cat# MBS1266676

CHRM1 cDNA Clone – Cholinergic Receptor, Muscarinic 1 (Human)

Name: CHRM1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266676
Price: 555 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266676

MBS1266676 is a cDNA clone targeting CHRM1. More details

$555 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CHRM1, cDNA Clone

Full Product Name

CHRM1 cDNA Clone

Product Gene Name

CHRM1 cdna clone

Sequence

atgaacactt cagccccacc tgctgtcagc cccaacatca ccgtcctggc accaggaaag ggtccctggc aagtggcctt cattgggatc accacgggcc tcctgtcgct agccacagtg acaggcaacc tgctggtact catctctttc aaggtcaaca cggagctcaa gacagtcaat aactacttcc tgctgagcct ggcctgtgct gacctcatca tcggtacctt ctccatgaac ctctatacca cgtacctgct catgggccac tgggctctgg gcacgctggc ttgtgacctc tggctggccc tggactatgt ggccagcaat gcctccgtca tgaatctgct gctcatcagc tttgaccgct acttctccgt gactcggccc ctgagctacc gtgccaagcg cacaccccgc cgggcagctc tgatgatcgg cctggcctgg ctggtttcct ttgtgctctg ggccccagcc atcctcttct ggcagtacct ggtaggggag cggacagtgc tagctgggca gtgctacatc cagttcctct cccagcccat catcaccttt ggcacagcca tggctgcctt ctacctccct gtcacagtca tgtgcacgct ctactggcgc atctaccggg agacagagaa ccgagcacgg gagctggcag cccttcaggg ctccgagacg ccaggcaaag ggggtggcag cagcagcagc tcagagaggt ctcagccagg ggctgagggc tcaccagaga ctcctccagg ccgctgctgt cgctgctgcc gggcccccag gctgctgcag gcctacagct ggaaggaaga agaggaagag gacgaaggct ccatggagtc cctcacatcc tcagagggag aggagcctgg ctccgaagtg gtgatcaaga tgccaatggt ggaccccgag gcacaggccc ccaccaagca gcccccacgg agctccccaa atacagtcaa gaggccgact aagaaagggc gtgatcgagc tggcaagggc cagaagcccc gtggaaagga gcagctggcc aagcggaaga ccttctcgct ggtcaaggag aagaaggcgg ctcggaccct gagtgccatc ctcctggcct tcatcctcac ctggacaccg tacaacatca tggtgctggt gtccaccttc tgcaaggact gtgttcccga gaccctgtgg gagctgggct actggctgtg ctacgtcaac agcaccatca accccatgtg ctacgcactc tgcaacaaag ccttccggga cacctttcgc ctgctgctgc tttgccgctg ggacaagaga cgctggcgca agatccccaa gcgccctggc tccgtgcacc gcactccctc ccgccaatgc tga

Molecular Weight

50,748 Da

OMIM

118510

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CHRM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHRM1. It may not necessarily be applicable to this product.

NCBI GI #

33871631

NCBI GeneID

1128

NCBI Accession #

BC007740

UniProt Secondary Accession #

Q96RH1

UniProt Related Accession #

P11229

NCBI Official Full Name

Homo sapiens cholinergic receptor, muscarinic 1, mRNA

NCBI Official Synonym Full Names

cholinergic receptor muscarinic 1

NCBI Official Symbol

CHRM1

NCBI Official Synonym Symbols

M1; HM1; M1R

UniProt Protein Name

Muscarinic acetylcholine receptor M1

Protein Family

Muscarinic acetylcholine receptor

UniProt Gene Name

CHRM1

UniProt Entry Name

ACM1_HUMAN

NCBI Protein Information

muscarinic acetylcholine receptor M1

NCBI Summary for CHRM1

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]

UniProt Comments for CHRM1

mAChR m1: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: membrane; plasma membrane; synapse

Molecular Function: phosphoinositide phospholipase C activity

Biological Process: acetylcholine receptor signaling, muscarinic pathway; cell proliferation; G-protein coupled receptor protein signaling pathway; muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway; muscarinic acetylcholine receptor, phospholipase C activating pathway; nervous system development; positive regulation of cell proliferation; positive regulation of ion transport; protein kinase C activation; protein modification process; regulation of vascular smooth muscle contraction; signal transduction; synaptic transmission, cholinergic

Research Articles on CHRM1

1. The rs2067477 muscarinic M1 receptor genotype is associated with grey matter volume in schizophrenia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CHRM1 cdna clone

Products by Pathway	Pathway Diagram
Amine Ligand-binding Receptors Pathway antibodies	Amine Ligand-binding Receptors Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Cholinergic Synapse Pathway antibodies	Cholinergic Synapse Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with CHRM1 cdna clone

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>14 publications with CHRM1 and Mental Disorders
Nervous System Diseases Antibodies	>5 publications with CHRM1 and Nervous System Diseases
Inflammation Antibodies	>2 publications with CHRM1 and Inflammation
Cognition Disorders Antibodies	>2 publications with CHRM1 and Cognition Disorders
Dementia Antibodies	>2 publications with CHRM1 and Dementia
Cardiovascular Diseases Antibodies	>1 publications with CHRM1 and Cardiovascular Diseases
Poisoning Antibodies	>1 publications with CHRM1 and Poisoning
Muscular Diseases Antibodies	>1 publications with CHRM1 and Muscular Diseases
Weight Loss Antibodies	>1 publications with CHRM1 and Weight Loss
Basal Ganglia Diseases Antibodies	>1 publications with CHRM1 and Basal Ganglia Diseases

Organs/Tissues associated with CHRM1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>13 publications with CHRM1 and Brain
Kidney Antibodies	>3 publications with CHRM1 and Kidney
Eye Antibodies	>3 publications with CHRM1 and Eye
Lung Antibodies	>1 publications with CHRM1 and Lung
Prostate Antibodies	>1 publications with CHRM1 and Prostate