Human CKAP5 cDNA Clone Expression Plasmid – Cat# MBS1278659

CKAP5 cDNA Clone – Cytoskeleton Associated Protein 5 (Human)

Name: CKAP5 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278659
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278659

MBS1278659 is a cDNA clone targeting CKAP5. More details

$1060 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CKAP5, cDNA Clone

Full Product Name

CKAP5 cDNA Clone

Product Gene Name

CKAP5 cdna clone

Sequence

atgccagcca agcctgctcc acccactaaa gcaacttcta aaccaatggg agggtccgct ccagccaaat tccagcctgc atcagcacct gctgaagatt gtatttccag cagtacagaa cccaaacctg atccaaaaaa ggccaaagct ccaggattat cctctaaagc aaagagtgca caagggaaga agatgccaag caaaaccagc ttaaaggagg atgaagacaa atccgggcct atttttattg ttgttccaaa tggaaaagag caaaggatga aagatgaaaa aggattgaag gtgctaaagt ggaattttac taccccacgg gatgaataca ttgagcaact aaagactcaa atgtctagct gtgtggctaa atggttacaa gatgagatgt ttcactcaga ctttcagcat cataacaaag cccttgctgt tatggttgat cacttggaga gtgaaaaaga aggagttatt ggttgcctgg atcttatctt aaagtggctt accctgaggt tttttgacac caatacaagc gtcctgatga aagcactaga atatttaaaa ttgctcttca ccttgctaag tgaagaagaa tatcatctta ctgagaatga agcatcttcc ttcatcccct atcttgtcgt caaggttgga gaaccaaagg atgtcattcg taaagatgtt cgtgccatcc tgaaccggat gtgccttgtc tacccagcta gcaagatgtt tccctttatc atggaaggaa ccaaatccaa aaactctaag cagagagcag agtgcctgga agagctggga tgtctggttg agtcctatgg catgaatgtt tgccaaccaa ccccaggaaa agccttaaag gaaatagctg ttcacatagg agaccgtgac aatgctgtac gcaatgctgc actcaacacc attgtaacgg tgtacaatgt acatggggat caggtgttca aactgattgg aaatctttct gaaaaggata tgagcatgct cgaggagagg attaagcggt cagcaaagag accctctgct gcaccaatag aacaggtgga agagaaacct cagcgtgcac agaacataag ctccaatgcc aacatgttac gcaagggacc agctgaggac atgtcttcca aactcaacca agcccgaagc atgagtgggc atcctgaggc agcccagatg gtccgccgag aattccagct ggatctagat gagattgaga atgacaatgg tacagtccga tgtgaaatgc cagaacttgt tcagcacaaa ctggatgaca tttttgagcc agtccttatt cctgaaccca agatccgggc tgtttctcca cacttcgatg acatgcacag taatacagca tccacaatca atttcattat ctcccaagta gccagtggtg acatcaacac aagtatccaa gctctgacac agatcgatga ggtcctgaga caggaagaca aagctgaagc catgtccggc catattgatc agtttctgat agccactttt atgcagctaa gactcatcta caacacacac atggcagatg agaaattgga gaaggacgag atcatcaagt tgtatagctg tatcattggc aacatgattt cgctgtttca gatagagagc cttgcccggg aggcctccac tggagtacta aaagacctaa tgcatggcct catcacctta atgctggatt ctcggattga agatcttgag gaaggacaac aggtcatccg ctctgtgaac ctcttggtgg tgaaggttct ggagaagtca gaccagacca acatcctgag tgccctactt gttttgctcc aagacagcct gctagcaaca gccagttctc ccaaattctc agagcttgtt atgaagtgtc tctggagaat ggttcgactg ttgcctgata ccatcaatag cattaaccta gacagaattc ttctggatat ccacattttc atgaaggtct tccccaaaga gaaactgaag caatgcaaaa gtgaatttcc cataaggacc ctaaagaccc tgctacacac cttatgcaaa ttaaaagggc ccaagatcct ggaccaccta acgatgatcg acaacaaaaa cgagtctgag ctggaggccc atctctgccg gatgatgaag cacagtatgg accagactgg gagcaagtct gataaggaaa cagaaaaggg agcatctcga atagatgaaa aatcatcaaa ggccaaagtg aatgatttct tagctgagat ttttaagaag attggctcta aagaaaacac taaagaggga ctagcagagt tatatgaata taagaagaaa tactcagatg ctgacattga accatttctg aaaaattcct cacagttctt ccagagctat gtcgaaagag gccttcgggt gattgagatg gagagggagg gcaaaggtcg tatttccact tcaacaggca tctcccctca gatggaagtc acatgtgtgc ccacgcccac aagcacagtg tcctccatag gtaacacaaa tggggaagaa gtggggccat ctgtctactt ggaaaggcta aagatcctcc gacagcgatg tggtctggac aacacaaagc aagatgaccg acctcctttg acctctttgc tctccaaacc agcagttcct actgtcgcct cttccacaga catgctccac agcaaactct ctcagctccg ggagtcacgg gagcagcacc agcattcaga cctggattct aaccagactc actcttcagg aactgtgacc tcctcctcct ccacagctaa catagacgac ttgaaaaaaa gactggagag aataaagagc agtcgcaaat ga

Molecular Weight

226,258 Da

OMIM

611142

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CKAP5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CKAP5. It may not necessarily be applicable to this product.

NCBI GI #

23272299

NCBI GeneID

9793

NCBI Accession #

BC035554

UniProt Secondary Accession #

Q05D70; Q0VAX7; Q0VAX8; Q14668; Q2TA89; Q6NSH4

UniProt Related Accession #

Q14008

NCBI Official Full Name

Homo sapiens cytoskeleton associated protein 5, mRNA

NCBI Official Synonym Full Names

cytoskeleton associated protein 5

NCBI Official Symbol

CKAP5

NCBI Official Synonym Symbols

TOG; MSPS; TOGp; CHTOG; ch-TOG

UniProt Protein Name

Cytoskeleton-associated protein 5

UniProt Synonym Protein Names

Colonic and hepatic tumor overexpressed gene protein; Ch-TOG

Protein Family

Cytoskeleton-associated protein

UniProt Gene Name

CKAP5

UniProt Synonym Gene Names

KIAA0097; Ch-TOG

UniProt Entry Name

CKAP5_HUMAN

NCBI Protein Information

cytoskeleton-associated protein 5

NCBI Summary for CKAP5

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

UniProt Comments for CKAP5

CKAP5: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. Belongs to the TOG/XMAP215 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: cell-cell adherens junction; centrosome; cytosol; gamma-tubulin complex; membrane; microtubule cytoskeleton; protein complex; spindle pole

Molecular Function: protein binding

Biological Process: centrosome organization and biogenesis; establishment and/or maintenance of microtubule cytoskeleton polarity; G2/M transition of mitotic cell cycle; RNA transport; sister chromatid cohesion; spindle organization and biogenesis

Research Articles on CKAP5

1. Data show that cytoskeleton associated protein 5 (chTOG) only weakly promotes importin-regulated microtubule nucleation, but acts synergistically with microtubule- associated protein TPX2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CKAP5 cdna clone

Products by Pathway	Pathway Diagram
Aurora A Signaling Pathway antibodies	Aurora A Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Centrosome Maturation Pathway antibodies	Centrosome Maturation Pathway Diagram
G2/M Transition Pathway antibodies	G2/M Transition Pathway Diagram
Loss Of Nlp From Mitotic Centrosomes Pathway antibodies	Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
Loss Of Proteins Required For Interphase Microtubule OrganizationÃ‚Â From The Centrosome Pathway antibodies	Loss Of Proteins Required For Interphase Microtubule OrganizationÃ‚Â From The Centrosome Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Anaphase Pathway antibodies	Mitotic Anaphase Pathway Diagram
Mitotic G2-G2/M Phases Pathway antibodies	Mitotic G2-G2/M Phases Pathway Diagram

Diseases associated with CKAP5 cdna clone

Disease Name	Pubmed Publications
Carcinoma Antibodies	>2 publications with CKAP5 and Carcinoma