Human CRAT cDNA Clone Expression Plasmid – Cat# MBS1266028

CRAT cDNA Clone – Carnitine Acetyltransferase (Human)

Name: CRAT cDNA Clone; Carnitine Acetyltransferase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266028
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266028

MBS1266028 is a cDNA clone targeting CRAT. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CRAT, cDNA Clone

Full Product Name

CRAT cDNA Clone

Product Gene Name

CRAT cdna clone

Sequence

atgttagcct tcgctgccag gaccgtggtg aagcctctgg gcttcctgaa gcccttctcc ttgatgaagg cttccagccg cttcaaggca caccaggatg cactgccacg gctgcccgtg ccccctctcc agcagtccct ggaccactac ctgaaggcgc tgcagcccat cgtgagtgag gaggagtggg cccacaccaa gcagctggtg gatgagtttc aggcctcagg aggtgtaggg gagcgcctgc agaaggggct ggagcgtcgg gccaggaaga cggagaactg gctgtctgag tggtggctca agaccgccta cctccagtac cgccagcctg tggtcatcta ctcgagccca ggcgtgatgc tacccaagca ggacttcgtg gacctgcagg gtcagctccg atttgctgcc aaactcattg agggtgtgtt ggatttcaag gtcatgattg acaacgagac cctgcccgtg gagtacctgg gggggaagcc actgtgcatg aaccagtact atcagatctt gtcctcctgc cgagtgccgg gccccaagca ggacacagtc agcaacttca gcaagaccaa gaagcctccc acgcacatca ccgtggtaca caactaccag ttttttgagc tggatgtgta ccacagtgac gggacacccc tcactgcgga tcagatcttt gtgcagctgg agaagatctg gaactcatcc ctacagacca acaaggagcc tgtgggcatc ctcacctcca accaccgcaa ctcctgggcc aaggcataca acaccctcat caaagacaag gtgaaccggg attccgtgcg ctccatccag aagaaacccg agcttgtgcg gtctcccatg gtgcccctgc ccatgcccaa gaagctgcgg ttcaacatca cccccgagat caagagcgac atcgagaagg ccaagcagaa cctcagcatc atgatccagg acctggatat caccgtgatg gtgttccacc attttggaaa agacttcccc aagtcggaga agctaagccc agatgccttc atccagatgg ctttgcagct ggcctactac aggatctacg gacaggcatg tgccacctat gaaagtgcct ccctgcgcat gtttcacctg ggccgcaccg acaccatccg ctcggcttcc atggactcac tcacctttgt caaggccatg gatgactcca gcgtcacgga gcaccagaag gtggagctgc tgcggaaggc cgtgcaggcc caccgaggct acaccgaccg ggccatccgc ggggaggcct ttgatcgaca cctgctgggc ctgaagctgc aggccatcga ggacctggtg agcatgcccg acatcttcat ggacacctcc tacgccatcg ccatgcactt ccacctctcc accagccagg tccctgccaa gacagactgt gtcatgttct tcgggcccgt ggtccccgac ggctacggtg tctgctataa ccccatggag gcccacatca acttctccct gtcggcctac aacagctgcg cggagaccaa cgccgcccgc ctggcgcatt acctggagaa ggcgctcctg gacatgcgtg ccctgctgca gagccacccc cgggccaagc tctga

Molecular Weight

61,870 Da

OMIM

600184

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CRAT cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRAT. It may not necessarily be applicable to this product.

NCBI GI #

33872619

NCBI GeneID

1384

NCBI Accession #

BC000723

UniProt Secondary Accession #

Q5T952; Q9BW16

UniProt Related Accession #

P43155

NCBI Official Full Name

Homo sapiens carnitine acetyltransferase, mRNA

NCBI Official Synonym Full Names

carnitine O-acetyltransferase

NCBI Official Symbol

CRAT

NCBI Official Synonym Symbols

CAT1

UniProt Protein Name

Carnitine O-acetyltransferase

UniProt Synonym Protein Names

Carnitine acetyltransferase; CAT; CrAT

Protein Family

Carnitine O-acetyltransferase

UniProt Gene Name

CRAT

UniProt Synonym Gene Names

CAT1; Carnitine acetylase; CAT; CrAT

UniProt Entry Name

CACP_HUMAN

NCBI Protein Information

carnitine O-acetyltransferase

NCBI Summary for CRAT

This gene encodes carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

UniProt Comments for CRAT

CRAT: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Belongs to the carnitine/choline acetyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Acetyltransferase; EC 2.3.1.7

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: mitochondrion; peroxisomal matrix; peroxisome

Molecular Function: carnitine O-acetyltransferase activity; receptor binding

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA oxidase

Research Articles on CRAT

1. CrAT turned out to be active towards some but not all the BCAAO intermediates tested and no activity was found with dicarboxylic acyl-CoA esters.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CRAT cdna clone

Products by Pathway	Pathway Diagram
Beta-oxidation Of Pristanoyl-CoA Pathway antibodies	Beta-oxidation Of Pristanoyl-CoA Pathway Diagram
Beta-oxidation Of Very Long Chain Fatty Acids Pathway antibodies	Beta-oxidation Of Very Long Chain Fatty Acids Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Peroxisomal Lipid Metabolism Pathway antibodies	Peroxisomal Lipid Metabolism Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram

Diseases associated with CRAT cdna clone

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>13 publications with CRAT and Kidney Diseases
Inflammation Antibodies	>4 publications with CRAT and Inflammation
Drug Toxicity Antibodies	>3 publications with CRAT and Drug Toxicity
Cardiovascular Diseases Antibodies	>3 publications with CRAT and Cardiovascular Diseases
Nervous System Diseases Antibodies	>3 publications with CRAT and Nervous System Diseases
Abnormalities, Drug-Induced Antibodies	>2 publications with CRAT and Abnormalities, Drug-Induced
Hypertension Antibodies	>2 publications with CRAT and Hypertension
Insulin Resistance Antibodies	>2 publications with CRAT and Insulin Resistance
Muscular Diseases Antibodies	>1 publications with CRAT and Muscular Diseases
Hyperglycemia Antibodies	>1 publications with CRAT and Hyperglycemia

Organs/Tissues associated with CRAT cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>25 publications with CRAT and Blood
Bone Antibodies	>16 publications with CRAT and Bone
Kidney Antibodies	>15 publications with CRAT and Kidney
Muscle Antibodies	>7 publications with CRAT and Muscle
Heart Antibodies	>7 publications with CRAT and Heart
Liver Antibodies	>6 publications with CRAT and Liver
Lung Antibodies	>3 publications with CRAT and Lung
Connective Tissue Antibodies	>2 publications with CRAT and Connective Tissue
Brain Antibodies	>2 publications with CRAT and Brain
Intestine Antibodies	>1 publications with CRAT and Intestine