Human CREB1 cDNA Clone Expression Plasmid – Cat# MBS1276069

CREB1 cDNA Clone – Camp Responsive Element Binding Protein 1 (Human)

Name: CREB1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276069
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276069

MBS1276069 is a cDNA clone targeting CREB1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CREB1, cDNA Clone

Full Product Name

CREB1 cDNA Clone

Product Gene Name

CREB1 cdna clone

Sequence

atgaccatgg aatctggagc cgagaaccag cagagtggag atgcagctgt aacagaagct gaaaaccaac aaatgacagt tcaagcccag ccacagattg ccacattagc ccaggtatct atgccagcag ctcatgcaac atcatctgct cccaccgtaa ctctagtaca gctgcccaat gggcagacag ttcaagtcca tggagtcatt caggcggccc agccatcagt tattcagtct ccacaagtcc aaacagttca gtcttcctgt aaggacttaa aaagactttt ctccggaaca cagatttcaa ctattgcaga aagtgaagat tcacaggagt cagtggatag tgtaactgat tcccaaaagc gaagggaaat tctttcaagg aggccttcct acaggaaaat tttgaatgac ttatcttctg atgcaccagg agtgccaagg attgaagaag agaagtctga agaggagact tcagcacctg ccatcaccac tgtaacggtg ccaactccaa tttaccaaac tagcagtgga cagtatattg ccattaccca gggaggagca atacagctgg ctaacaatgg taccgatggg gtacagggcc tgcaaacatt aaccatgacc aatgcagcag ccactcagcc gggtactacc attctacagt atgcacagac cactgatgga cagcagatct tagtgcccag caaccaagtt gttgttcaag ctgcctctgg agacgtacaa acataccaga ttcgcacagc acccactagc actattgccc ctggagttgt tatggcatcc tccccagcac ttcctacaca gcctgctgaa gaagcagcac gaaagagaga ggtccgtcta atgaagaaca gggaagcagc tcgagagtgt cgtagaaaga agaaagaata tgtgaaatgt ttagaaaaca gagtggcagt gcttgaaaat caaaacaaga cattgattga ggagctaaaa gcacttaagg acctttactg ccacaaatca gattaa

Molecular Weight

25,445 Da

OMIM

123810

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CREB1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CREB1. It may not necessarily be applicable to this product.

NCBI GI #

14714955

NCBI GeneID

1385

NCBI Accession #

BC010636

UniProt Secondary Accession #

P21934; Q6V963; Q9UMA7

UniProt Related Accession #

P16220

NCBI Official Full Name

Homo sapiens cAMP responsive element binding protein 1, mRNA

NCBI Official Synonym Full Names

cAMP responsive element binding protein 1

NCBI Official Symbol

CREB1

NCBI Official Synonym Symbols

CREB; CREB-1

UniProt Protein Name

Cyclic AMP-responsive element-binding protein 1

Protein Family

Cyclic AMP-responsive element-binding protein

UniProt Gene Name

CREB1

UniProt Synonym Gene Names

CREB-1; cAMP-responsive element-binding protein 1

UniProt Entry Name

CREB1_HUMAN

NCBI Protein Information

cyclic AMP-responsive element-binding protein 1

NCBI Summary for CREB1

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

UniProt Comments for CREB1

CREB: a transcription factor of the leucine zipper family of DNA binding proteins. Binds as a homodimer to the cAMP-responsive element (CRE). Phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 2q34

Cellular Component: nucleoplasm; nucleus

Molecular Function: enzyme binding; identical protein binding; protein binding; RNA polymerase II transcription factor activity, enhancer binding; transcription cofactor activity; transcription factor activity

Biological Process: axon guidance; circadian rhythm; positive regulation of fat cell differentiation; positive regulation of lipid biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid phosphorylation; protein stabilization; response to glucagon stimulus; response to organic substance; signal transduction

Disease: Histiocytoma, Angiomatoid Fibrous

Research Articles on CREB1

1. demonstrated that GSK-3alpha is regulated by CREB in lung cancer and is required for the cell viability. These findings implicate CREB-GSK-3alpha axis as a novel therapeutic target for lung cancer treatment

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CREB1 cdna clone

Products by Pathway	Pathway Diagram
AKT Phosphorylates Targets In The Nucleus Pathway antibodies	AKT Phosphorylates Targets In The Nucleus Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram

Diseases associated with CREB1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>166 publications with CREB1 and Neoplasms
Nervous System Diseases Antibodies	>82 publications with CREB1 and Nervous System Diseases
Inflammation Antibodies	>51 publications with CREB1 and Inflammation
Depressive Disorder Antibodies	>36 publications with CREB1 and Depressive Disorder
Necrosis Antibodies	>35 publications with CREB1 and Necrosis
Drug Toxicity Antibodies	>34 publications with CREB1 and Drug Toxicity
Memory Disorders Antibodies	>31 publications with CREB1 and Memory Disorders
Learning Disorders Antibodies	>23 publications with CREB1 and Learning Disorders
Cognition Disorders Antibodies	>14 publications with CREB1 and Cognition Disorders
Fibrosis Antibodies	>12 publications with CREB1 and Fibrosis

Organs/Tissues associated with CREB1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>228 publications with CREB1 and Brain
Blood Antibodies	>115 publications with CREB1 and Blood
Muscle Antibodies	>55 publications with CREB1 and Muscle
Lung Antibodies	>51 publications with CREB1 and Lung
Bone Antibodies	>49 publications with CREB1 and Bone
Vascular Antibodies	>46 publications with CREB1 and Vascular
Liver Antibodies	>42 publications with CREB1 and Liver
Heart Antibodies	>29 publications with CREB1 and Heart
Kidney Antibodies	>26 publications with CREB1 and Kidney
Skin Antibodies	>23 publications with CREB1 and Skin