Human CRHBP cDNA Clone Expression Plasmid – Cat# MBS1272617

CRHBP cDNA Clone – Corticotropin Releasing Hormone Binding Protein (Human)

Name: CRHBP cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272617
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272617

MBS1272617 is a cDNA clone targeting CRHBP. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CRHBP, cDNA Clone

Full Product Name

CRHBP cDNA Clone

Product Gene Name

CRHBP cdna clone

Sequence

atgtcgccca acttcaaact tcagtgtcac ttcattctca tcttcctgac ggctctaaga ggggaaagcc ggtacctaga gctgagggaa gcggcggact acgatccttt cctgctcttc agcgccaacc tgaagcggga gctggctggg gagcagccgt accgccgcgc tctgcggtgc ctggacatgc tgagcctcca gggccagttc accttcaccg ccgaccggcc gcagctgcac tgcgcagcct tcttcatcag cgagcccgag gagttcatta ccatccacta cgaccaggtc tccatcgact gtcagggcgg cgacttcctg aaggtatttg atggttggat tctcaagggg gagaagttcc ccagttccca ggatcatcct ctcccctcag ctgagcggta catagatttc tgtgagagtg gtcttagcag gaggagcatc agatcttccc agaatgtggc catgatcttc ttccgagtcc atgaaccagg aaatggattc acattaacca taaagacaga ccccaacctc tttccttgca atgtcatttc tcagactcca aatggaaagt ttaccctggt agttccacac cagcatcgaa actgcagctt ctccataatt tatcctgtgg tgatcaaaat atctgatctt accctgggac acgtaaatgg tcttcagtta aagaaatcct cagcaggttg cgagggaata ggagactttg tggagctgct gggaggaact ggattggacc cttccaagat gacgccttta gctgatctct gctacccctt tcatggcccg gcccagatga aagttggctg tgacaacact gtggtgcgca tggtctccag tggaaaacac gtaaatcgtg tgacttttga gtatcgtcag ctggagccgt acgagctgga aaacccaaat ggaaacagta tcggggaatt ctgtttgtct ggtctttga

Molecular Weight

36,144 Da

OMIM

122559

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CRHBP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRHBP. It may not necessarily be applicable to this product.

NCBI GI #

17390069

NCBI GeneID

1393

NCBI Accession #

BC018038

UniProt Secondary Accession #

Q53F32; Q6FHT5

UniProt Related Accession #

P24387

NCBI Official Full Name

Homo sapiens corticotropin releasing hormone binding protein, mRNA

NCBI Official Synonym Full Names

corticotropin releasing hormone binding protein

NCBI Official Symbol

CRHBP

NCBI Official Synonym Symbols

CRFBP; CRF-BP

UniProt Protein Name

Corticotropin-releasing factor-binding protein

UniProt Synonym Protein Names

Corticotropin-releasing hormone-binding protein; CRH-BP

Protein Family

Corticotropin-releasing factor-binding protein

UniProt Gene Name

CRHBP

UniProt Synonym Gene Names

CRFBP; CRF-BP; CRF-binding protein; CRH-BP

UniProt Entry Name

CRHBP_HUMAN

NCBI Protein Information

corticotropin-releasing factor-binding protein

NCBI Summary for CRHBP

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]

UniProt Comments for CRHBP

CRHBP: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: dendrite; endoplasmic reticulum; extracellular space; Golgi apparatus; intracellular; microtubule; multivesicular body; nerve terminal; nucleus; perikaryon; secretory granule

Molecular Function: corticotropin-releasing hormone binding; peptide binding; protein binding

Biological Process: behavioral response to ethanol; cellular response to stress; female pregnancy; hormone-mediated signaling; inflammatory response; learning and/or memory; negative regulation of adrenocorticotropic hormone secretion; regulated secretory pathway; regulation of adrenocorticotropin hormone secretion; signal transduction; synaptic transmission, dopaminergic

Research Articles on CRHBP

1. These results suggest that the CRH and CRH-BP genes have no direct effect on Irritable bowel syndrome status.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CRHBP cdna clone

Disease Name	Pubmed Publications
Pain Antibodies	>3 publications with CRHBP and Pain
Inflammation Antibodies	>3 publications with CRHBP and Inflammation
Depressive Disorder Antibodies	>2 publications with CRHBP and Depressive Disorder
Premature Birth Antibodies	>2 publications with CRHBP and Premature Birth
Disease Models, Animal Antibodies	>1 publications with CRHBP and Disease Models, Animal
Nervous System Diseases Antibodies	>1 publications with CRHBP and Nervous System Diseases
Drug Toxicity Antibodies	>1 publications with CRHBP and Drug Toxicity
Edema Antibodies	>1 publications with CRHBP and Edema
Necrosis Antibodies	>1 publications with CRHBP and Necrosis

Organs/Tissues associated with CRHBP cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with CRHBP and Brain
Kidney Antibodies	>4 publications with CRHBP and Kidney
Placenta Antibodies	>4 publications with CRHBP and Placenta
Ovary Antibodies	>3 publications with CRHBP and Ovary
Skin Antibodies	>3 publications with CRHBP and Skin
Embryonic Tissue Antibodies	>2 publications with CRHBP and Embryonic Tissue
Adrenal Gland Antibodies	>2 publications with CRHBP and Adrenal Gland
Liver Antibodies	>2 publications with CRHBP and Liver
Connective Tissue Antibodies	>1 publications with CRHBP and Connective Tissue
Uterus Antibodies	>1 publications with CRHBP and Uterus