Human CTBP2 cDNA Clone Expression Plasmid – Cat# MBS1268391

CTBP2 cDNA Clone – C-Terminal Binding Protein 2 (Human)

Name: CTBP2 cDNA Clone; C-Terminal Binding Protein 2; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268391
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268391

MBS1268391 is a cDNA clone targeting CTBP2. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CTBP2, cDNA Clone

Full Product Name

CTBP2 cDNA Clone

Product Gene Name

CTBP2 cdna clone

Sequence

atgagaccag gacttccagg ccccacaggg ttgtgcgctc agacctcaag taggggccag aagagtgtac tgaaacagaa ggaatcttgt ggaatttggc agttgtacca ttttcttagc agaaaacagg agcccaggtg ggagccatgt gtgtcgggtt cctcgtcagg tgacggtgct gttgcggatc tcgcggatga gctgaggggg tatccagctt tgtgctgcac gcttcctgtc cactcataca ggtcgtgggc tggtatccgc ccccagatca tgaacggccc cctgcacccc cgccccctgg tggcgctgct ggacggccgc gactgcactg tggagatgcc catcctgaag gacctggcca ctgtggcctt ctgtgacgcg cagtcgacgc aggaaatcca cgagaaggtt ctaaacgaag ccgtgggcgc catgatgtac cacaccatca ccctcaccag ggaggacctg gagaagttca aggccctgag agtgatcgtg cggataggca gtggctatga caacgtggac atcaaggctg ccggcgagct cggaattgcc gtgtgcaaca tcccgtctgc agccgtggaa gagacagcgg actctaccat ctgccacatc ctcaacctgt accggaggaa cacgtggctg taccaggcac tgcgggaagg cacgcgggtt cagagcgtgg agcagatccg cgaggtggcc tcgggagcgg cccgcatccg tggggagacg ctgggcctca ttggctttgg tcgcacgggg caggcggttg cagttcgagc caaggccttt ggattcagcg tcatatttta tgacccctac ttgcaggatg ggatcgagcg gtccctgggc gtgcagaggg tctacaccct gcaggatttg ctgtatcaga gcgactgcgt ctccttgcac tgcaatctca acgaacataa ccaccacctc atcaatgact ttaccataaa gcagatgagg cagggagcat tccttgtgaa cgcagcccgt ggcggcctgg tggacgagaa agccttagca caagccctca aggagggcag gatacgaagg gcagccctcg acgtgcatga gtcagagccc ttcagctttg ctcagggtcc gttgaaagat gccccgaatc tcatctgcac tcctcacact gcctggtaca gtgagcaggc gtcactggag atgagggagg cagctgccac cgagatccgc cgagccatca caggtcgcat cccagaaagc ttaagaaatt gtgtgaacaa ggaattcttt gtcacatcag cgccttggtc agtaatagac cagcaagcaa ttcatcctga gctcaatggt gccacataca gatatccgcc aggcatcgtg ggtgtggctc caggaggact tcctgcagcc atggaaggga tcatccctgg aggcatccca gtgactcaca acctcccgac agtggcacat ccttcccaag cgccctctcc caaccagccc acaaaacacg gggacaatcg agagcacccc aacgagcaat ag

Molecular Weight

106,187 Da

OMIM

602619

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CTBP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CTBP2. It may not necessarily be applicable to this product.

NCBI GI #

34192801

NCBI GeneID

1488

NCBI Accession #

BC037900

UniProt Secondary Accession #

O43449; Q5SQP7; Q69YI3; Q86SV0; Q9H2T8; A8K2X5; D3DRF5

UniProt Related Accession #

P56545

NCBI Official Full Name

Homo sapiens C-terminal binding protein 2, mRNA

NCBI Official Synonym Full Names

C-terminal binding protein 2

NCBI Official Symbol

CTBP2

UniProt Protein Name

C-terminal-binding protein 2

Protein Family

C-terminal-binding protein

UniProt Gene Name

CTBP2

UniProt Synonym Gene Names

CtBP2

UniProt Entry Name

CTBP2_HUMAN

NCBI Protein Information

C-terminal-binding protein 2

NCBI Summary for CTBP2

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

UniProt Comments for CTBP2

CTBP2: Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: nucleus; transcriptional repressor complex

Molecular Function: protein binding; protein homodimerization activity; transcription corepressor activity

Biological Process: negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of retinoic acid receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; viral genome replication; white fat cell differentiation

Research Articles on CTBP2

1. Our results indicated that CCNH/CDK7-CtBP2 axis may augment ESCC cell migration, and targeting the interaction of both may provide a novel therapeutic target of esophageal squamous cell carcinoma .

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CTBP2 cdna clone

Products by Pathway	Pathway Diagram
Chronic Myeloid Leukemia Pathway antibodies	Chronic Myeloid Leukemia Pathway Diagram
Chronic Myeloid Leukemia Pathway antibodies	Chronic Myeloid Leukemia Pathway Diagram
Neural Crest Differentiation Pathway antibodies	Neural Crest Differentiation Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Pathways In Cancer antibodies	Pathways In Cancer Diagram
Wnt Signaling Pathway NetPath antibodies	Wnt Signaling Pathway NetPath Diagram
Wnt Signaling Pathway And Pluripotency antibodies	Wnt Signaling Pathway And Pluripotency Diagram
Wnt Signaling Pathway antibodies	Wnt Signaling Pathway Diagram

Diseases associated with CTBP2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>17 publications with CTBP2 and Neoplasms
Carcinoma Antibodies	>7 publications with CTBP2 and Carcinoma
Nervous System Diseases Antibodies	>6 publications with CTBP2 and Nervous System Diseases
Breast Neoplasms Antibodies	>5 publications with CTBP2 and Breast Neoplasms
Adenocarcinoma Antibodies	>3 publications with CTBP2 and Adenocarcinoma
Cell Transformation, Neoplastic Antibodies	>3 publications with CTBP2 and Cell Transformation, Neoplastic
Skin Diseases Antibodies	>3 publications with CTBP2 and Skin Diseases
Congenital Abnormalities Antibodies	>3 publications with CTBP2 and Congenital Abnormalities
Prostatic Neoplasms Antibodies	>3 publications with CTBP2 and Prostatic Neoplasms
Pancreatic Neoplasms Antibodies	>1 publications with CTBP2 and Pancreatic Neoplasms

Organs/Tissues associated with CTBP2 cdna clone

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>56 publications with CTBP2 and Eye
Nerve Antibodies	>54 publications with CTBP2 and Nerve
Brain Antibodies	>20 publications with CTBP2 and Brain
Ear Antibodies	>16 publications with CTBP2 and Ear
Embryonic Tissue Antibodies	>7 publications with CTBP2 and Embryonic Tissue
Blood Antibodies	>7 publications with CTBP2 and Blood
Lung Antibodies	>4 publications with CTBP2 and Lung
Prostate Antibodies	>3 publications with CTBP2 and Prostate
Heart Antibodies	>3 publications with CTBP2 and Heart
Adipose Tissue Antibodies	>2 publications with CTBP2 and Adipose Tissue