Human DDX20 cDNA Clone Expression Plasmid – Cat# MBS1266975

DDX20 cDNA Clone – DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (Human)

Name: DDX20 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266975
Price: 920 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266975

MBS1266975 is a cDNA clone targeting DDX20. More details

$920 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DDX20, cDNA Clone

Full Product Name

DDX20 cDNA Clone

Product Gene Name

DDX20 cdna clone

Sequence

atggcggcgg catttgaagc ctcgggagcc ttagcggcag tggcgactgc tatgccggct gagcatgtgg ccgtgcaggt cccggcccca gagccaacac ccgggcctgt gaggatcctg cggaccgctc aggatctcag cagcccgcgg acccgcacgg gggatgtgct gttggcggag ccggccgact tcgagtcact gctgctttcg cggccggtgc tggaggggct gcgggcggcc ggcttcgaga ggccctcgcc ggtgcagctc aaggccatcc cgctggggcg ctgcgggctc gatttaattg ttcaagctaa atctggcacc gggaaaacct gtgtgttctc caccatagct ttggactctc ttgttcttga aaacttaagt acccagattt tgatcttggc tcctacaaga gaaattgctg tacagataca ttctgttatt acagccattg gaataaaaat ggaaggctta gagtgtcatg tctttattgg agggacccca ttatcacaag acaaaaccag acttaaaaag tgtcatattg ctgttggatc tcctggcaga attaagcaac tcatagaact tgactacttg aacccaggca gtatacgcct ctttattctt gatgaagcag ataagctttt agaagaaggc agcttccagg agcaaataaa ttggatttat tcttccttgc ctgccagtaa acagatgctg gcagtatcag ctacttatcc cgaatttttg gctaatgctt tgacaaagta catgagagat cccacttttg taagactgaa ttccagtgat ccaagtctca taggtttgaa gcagtattac aaagttgtca attcataccc tttggcacat aaggtttttg aggaaaagac tcagcattta caggaactgt tcagcagaat tccatttaat caagctttag tcttttctaa tttgcacagc agagcacaac atttggctga tatcctttct tctaaaggct ttcctgctga gtgcatttca ggcaatatga atcagaatca gcgtcttgat gctatggcta aactgaagca ctttcattgc agagtcctca tttccacaga tttgacttct cgtgggattg atgctgagaa ggtgaatctg gttgtaaatc tggatgtacc attggattgg gagacataca tgcatcggat tgggagagct ggccgttttg gtacattggg gctgacagtg acctactgtt gccggggaga ggaagaaaat atgatgatga gaattgccca gaaatgtaat atcaaccttc tccctttacc agatcccatt ccttctggtc tgatggaaga atgtgtggat tgggatgtgg aagttaaagc tgctgtgcat acatatggta tagcaagtgt acctaaccaa cccttaaaaa agcaaattca gaaaatagag agaacccttc aaattcagaa agctcatggt gaccacatgg cttcctctag aaataattct gtatctggac tatcagtcaa atcaaaaaat aataccaaac aaaagcttcc tgtgaaaagc cactcagaat gtggaatcat agaaaaagca acatcaccaa aagaactggg ctgtgacagg caatccgaag agcaaatgaa gaattctgtt cagactcccg ttgaaaactc caccaacagt cagcaccagg tcaaagaagc tttacctgtg tcactccccc agattccttg tctgtcttcc tttaaaatcc atcagccata cacgttgact tttgctgaat tggtagagga ttatgaacat tatattaaag aggggttaga gaaacctgtg gaaatcatca ggcactacac aggccctggg gatcagactg tgaatcctca aaatggtttt gtgagaaata aagttactga acagagagtc cctgtattgg caagtagtag ccaatctgga gactctgaga gtgacagtga ttcttacagc tcaagaacct cttcccagag caaaggaaat aagtcatact tggaaggctc ttctgataat cagctgaaag actctgaatc tacgcctgtg gatgatcgta tttctttgga acaaccacca aatggaagtg acacccccaa tccagagaaa tatcaagaat cacctggaat ccagatgaag acaagactta aagagggggc tagccagaga gctaagcaga gccggagaaa cctacccagg cggtcttcct tcagattgca gactgaagcc caggaagatg attggtatga ctgtcatagg gaaatacgtc tgagtttttc tgatacctat caggattatg aggagtactg gagagcttac tacagggcat ggcaagaata ttatgctgcc gcttctcatt catattattg gaatgctcag agacatccaa gttggatggc agcttatcac atgaatacca tttatctaca agaaatgatg catagtaacc agtga

Molecular Weight

14,272 Da

OMIM

606168

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DDX20 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DDX20. It may not necessarily be applicable to this product.

NCBI GI #

15079430

NCBI GeneID

11218

NCBI Accession #

BC011556

UniProt Secondary Accession #

Q96F72; Q9NVM3; Q9UF59; Q9UIY0; Q9Y659; B4DWV7

UniProt Related Accession #

Q9UHI6

NCBI Official Full Name

Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 20, mRNA

NCBI Official Synonym Full Names

DEAD-box helicase 20

NCBI Official Symbol

DDX20

NCBI Official Synonym Symbols

DP103; GEMIN3

UniProt Protein Name

Probable ATP-dependent RNA helicase DDX20

UniProt Synonym Protein Names

Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3

Protein Family

Probable ATP-dependent RNA helicase

UniProt Gene Name

DDX20

UniProt Synonym Gene Names

DP103; GEMIN3

UniProt Entry Name

DDX20_HUMAN

NCBI Protein Information

probable ATP-dependent RNA helicase DDX20

NCBI Summary for DDX20

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]

UniProt Comments for DDX20

GEMIN3: an ubiquitous DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. Interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.

Protein type: EC 3.6.4.13; Nuclear receptor co-regulator; RNA splicing; Helicase

Chromosomal Location of Human Ortholog: 1p21.1-p13.2

Cellular Component: cytoplasm; cytoskeleton; cytosol; membrane; nucleoplasm; nucleus; SMN complex

Molecular Function: ATP-dependent RNA helicase activity; protein binding

Biological Process: assembly of spliceosomal tri-snRNP; negative regulation of transcription from RNA polymerase II promoter; nuclear import; positive regulation of apoptosis; RNA processing; RNA secondary structure unwinding; spliceosomal snRNP biogenesis

Research Articles on DDX20

1. In stage-adjusted analysis, the nominal associations of DDX20-rs197412, PTGS2-rs5275, and HSPA5-rs391957 with DFS were detected. However, after FDR correction none of these polymorphisms remained significantly associated with the survival outcomes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DDX20 cdna clone

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Of Non-coding RNA Pathway antibodies	Metabolism Of Non-coding RNA Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
Survival Motor Neuron (SMN) Complex Pathway antibodies	Survival Motor Neuron (SMN) Complex Pathway Diagram
MRNA Processing Pathway antibodies	MRNA Processing Pathway Diagram
SnRNP Assembly Pathway antibodies	SnRNP Assembly Pathway Diagram

Diseases associated with DDX20 cdna clone

Disease Name	Pubmed Publications
Atrophy Antibodies	>12 publications with DDX20 and Atrophy
Neoplasms Antibodies	>4 publications with DDX20 and Neoplasms
Liver Diseases Antibodies	>2 publications with DDX20 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with DDX20 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>2 publications with DDX20 and Carcinoma, Hepatocellular
Congenital Abnormalities Antibodies	>1 publications with DDX20 and Congenital Abnormalities
Neoplasms, Experimental Antibodies	>1 publications with DDX20 and Neoplasms, Experimental
Death Antibodies	>1 publications with DDX20 and Death
Necrosis Antibodies	>1 publications with DDX20 and Necrosis

Organs/Tissues associated with DDX20 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with DDX20 and Liver
Blood Antibodies	>3 publications with DDX20 and Blood
Embryonic Tissue Antibodies	>2 publications with DDX20 and Embryonic Tissue
Uncharacterized Tissue Antibodies	>2 publications with DDX20 and Uncharacterized Tissue
Ovary Antibodies	>2 publications with DDX20 and Ovary
Brain Antibodies	>2 publications with DDX20 and Brain
Adrenal Gland Antibodies	>1 publications with DDX20 and Adrenal Gland
Placenta Antibodies	>1 publications with DDX20 and Placenta
Kidney Antibodies	>1 publications with DDX20 and Kidney
Muscle Antibodies	>1 publications with DDX20 and Muscle