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DECR2 cDNA Clone – Peroxisomal 2,4-Dienoyl-Coa Reductase

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200762

Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DECR2, cDNA Clone
Full Product Name
DECR2
Product Gene Name
DECR2 cdna clone
Product Synonym Names
PDCR; SDR17C1
Sequence
Nucleotide Sequence: ATGGCCCAGC CGCCGCCCGA CGTGGAGGGG GACGACTGTC TCCCCGCGTA CCGCCACCTC TTCTGCCCGG ACCTGCTGCG GGACAAAGTG GCCTTCATCA CAGGAGGCGG CTCTGGGATT GGGTTCCGGA TTGCTGAGAT TTTCATGCGG CACGGCTGCC ATACGGTGAT TGCCAGTAGG AGCCTGCCGC GAGTGCTGAC GGCCGCCAGG AAGCTGGCTG GGGCCACCGG CCGGCGCTGC CTCCCTCTCT CTATGGACGT CCGAGCGCCC CCAGCTGTCA TGGCCGCCGT GGACCAGGCT CTGAAGGAGT TTGGCAGAAT CGACATTCTC ATTAACTGTG CGGCCGGGAA CTTCCTGTGC CCCGCTGGCG CCTTGTCCTT CAACGCCTTC AAGACCGTGA TGGACATCGA TACCAGCGGC ACCTTCAATG TGTCTCGTGT GCTCTATGAG AAGTTCTTCC GGGACCACGG AGGGGTGATC GTGAACATCA CTGCCACCCT GGGGAACCGG GGGCAGGCGC TCCAGGTGCA TGCAGGCTCC GCCAAGGCCG CTGTGGACGC GATGACGCGG CACTTGGCTG TGGAGTGGGG TCCCCAAAAC ATCCGCGTCA ACAGCCTCGC CCCTGGCCCC ATCAGTGGCA CAGAGGGGCT CCGGCGACTG GGTGGCCCTC AGGCCAGCCT GAGCACCAAG GTCACTGCCA GCCCGCTGCA GAGGCTGGGG AACAAGACCG AGATCGCCCA CAGCGTGCTC TACCTGGCCA GCCCTCTGGC TTCCTACGTG ACGGGGGCCG TGCTGGTGGC CGATGGCGGG GCATGGTTGA CGTTCCCAAA CGGTGTCAAA GGGCTGCCGG ATTTCGCATC CTTCTCTGCT AAGCTCTAG< br>
Tra nslation Sequence: MAQPPPDVEG DDCLPAYRHL FCPDLLRDKV AFITGGGSGI GFRIAEIFMR HGCHTVIASR SLPRVLTAAR KLAGATGRRC LPLSMDVRAP PAVMAAVDQA LKEFGRIDIL INCAAGNFLC PAGALSFNAF KTVMDIDTSG TFNVSRVLYE KFFRDHGGVI VNITATLGNR GQALQVHAGS AKAAVDAMTR HLAVEWGPQN IRVNSLAPGP ISGTEGLRRL GGPQASLSTK VTASPLQRLG NKTEIAHSVL YLASPLASYV TGAVLVADGG AWLTFPNGVK GLPDFASFSA KL
Form/Format
Lyophilized
Preparation and Storage
Store the plasmid at -20 degree C.
3D Structure
ModBase 3D Structure for Q9NUI1
Species
Human
Chromosome Location
16p13.3
OMIM Reference Number
615839
cDNA Size
879bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

Product Categories/Family for DECR2 cdna clone

Metabolism; Signal Transduction

Other Notes

Small volumes of DECR2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DECR2 purchase

MBS200762 is a cDNA clone targeting DECR2.

Additional Details

NCBI/Uniprot data below describe general gene information for DECR2. It may not necessarily be applicable to this product.

NCBI GI #
10190704
NCBI GeneID
26063
NCBI Accession #
NP_065715.1
UniProt Primary Accession #
Q9NUI1
UniProt Related Accession #
Q9NUI1
GenBank Nucleotide #
NM_020664.3
NCBI Official Full Name
peroxisomal 2,4-dienoyl-CoA reductase
NCBI Official Synonym Full Names
2,4-dienoyl-CoA reductase 2
NCBI Official Symbol
DECR2
NCBI Official Synonym Symbols
PDCR; SDR17C1
UniProt Protein Name
Peroxisomal 2,4-dienoyl-CoA reductase
UniProt Synonym Protein Names
2,4-dienoyl-CoA reductase 2
UniProt Gene Name
DECR2
UniProt Synonym Gene Names
PDCR; pDCR
UniProt Entry Name
DECR2_HUMAN
NCBI Protein Information
peroxisomal 2,4-dienoyl-CoA reductase

UniProt Comments for DECR2

DECR2: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.3.1.34

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: peroxisomal membrane

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; receptor binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: unsaturated fatty acid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DECR2 cdna clone

 Products by Pathway  Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
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