Human DGKE cDNA Clone Expression Plasmid – Cat# MBS1277936

DGKE cDNA Clone – Diacylglycerol Kinase, Epsilon 64kDa (Human)

Name: DGKE cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1277936
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277936

MBS1277936 is a cDNA clone targeting DGKE. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DGKE, cDNA Clone

Full Product Name

DGKE cDNA Clone

Product Gene Name

DGKE cdna clone

Sequence

atggaagcgg agaggcggcc ggcgccgggc tcgccctccg agggcctgtt tgcggacggg cacctgatct tgtggacgct gtgctcggtc ctgctgccgg tgttcatcac cttctggtgt agcctccagc ggtcgcgccg gcagctgcac cgcagggaca tcttccgcaa gagcaagcac gggtggcgcg acacggacct gttcagccag cccacctact gctgcgtgtg cgcgcagcac attctgcagg gcgccttctg cgactgctgc gggctccgcg tggacgaggg ctgcctcagg aaggccgaca agcgcttcca gtgcaaggag attatgctca agaatgacac caaggtcctg gacgccatgc cccaccactg gatccggggc aacgtgcccc tgtgcagtta ctgtatggtt tgcaagcagc agtgtggctg tcaacccaag ctttgcgatt acaggtgcat ttggtgccag aaaacagtac atgatgagtg catgaaaaat agtttaaaga atgaaaaatg tgattttgga gaattcaaaa acctaatcat tccaccaagt tatttaacct ccattaatca gatgcgtaaa gacaaaaaaa cagattatga agtgctagcc tctaagcttg gaaagcagtg gaccccatta ataatcctgg ccaactctcg tagtggaact aatatgggag aaggactgtt gggagaattt aggatcttgt tgaatccagt ccaggttttt gatgtaacta aaactcctcc tatcaaagcc ctacaactct gtactcttct cccatattat tcagctcgag tacttgtttg tggaggggat gggactgtag ggtgggtcct ggatgcagtt gatgacatga agattaaggg acaagaaaag tacattccac aagttgcagt tttgcctctg ggaacaggca acgatctatc caatacattg ggttggggta caggttatgc tggagaaatt ccagttgcgc aggttttgcg aaatgtaatg gaagcagatg gaattaaact agatcgatgg aaagttcaag taacaaataa aggatactac aacttaagaa aacccaagga attcacaatg aacaactatt tttctgttgg acctgatgct ctcatggctc tcaattttca tgctcatcgt gagaaggcac catctctgtt ttctagcaga attcttaata aggcggttta cttattctat ggaaccaaag attgtttagt gcaagaatgt aaagatttga ataaaaaagt tgagctagaa ctggatggtg agcgagtagc actgcccagc ttggaaggta ttatagttct gaacatcgga tactggggcg gtggctgcag actatgggaa gggatggggg acgagactta ccctctagcc aggcatgacg atggtctgct ggaagtcgtt ggagtatatg ggtctttcca ctgtgctcag attcaagtaa aactggctaa tccttttcga ataggacagg cacatacagt gaggctgatt ttgaagtgct ccatgatgcc aatgcaggtg gatggggagc cttgggccca agggccctgc actgtcacca taactcacaa gacacatgca atgatgttat atttctctgg agaacaaaca gatgatgaca tctctagtac ttcggatcaa gaagatataa aggcgactga atag

Molecular Weight

20,452 Da

OMIM

601440

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DGKE cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DGKE. It may not necessarily be applicable to this product.

NCBI GI #

120659969

NCBI GeneID

8526

NCBI Accession #

BC130629

UniProt Secondary Accession #

Q8TBM4; Q9UKQ3

UniProt Related Accession #

P52429

NCBI Official Full Name

Homo sapiens diacylglycerol kinase, epsilon 64kDa, mRNA

NCBI Official Synonym Full Names

diacylglycerol kinase epsilon

NCBI Official Symbol

DGKE

NCBI Official Synonym Symbols

DGK; AHUS7; DAGK5; DAGK6; NPHS7

UniProt Protein Name

Diacylglycerol kinase epsilon

UniProt Synonym Protein Names

Diglyceride kinase epsilon; DGK-epsilon

Protein Family

Diacylglycerol kinase

UniProt Gene Name

DGKE

UniProt Synonym Gene Names

DAGK5; DAG kinase epsilon; DGK-epsilon

UniProt Entry Name

DGKE_HUMAN

NCBI Protein Information

diacylglycerol kinase epsilon

NCBI Summary for DGKE

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008]

UniProt Comments for DGKE

DGKE: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. Belongs to the eukaryotic diacylglycerol kinase family.

Protein type: Membrane protein, integral; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; EC 2.7.1.107; Membrane protein, multi-pass; Lipid Metabolism - glycerolipid; Kinase, lipid

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: cytoplasm; membrane; plasma membrane

Molecular Function: diacylglycerol kinase activity

Biological Process: phospholipid biosynthetic process; platelet activation

Disease: Nephrotic Syndrome, Type 7

Research Articles on DGKE

1. Letter/Case Report: atypical haemolytic uraemic syndrome in a Japanese patient with DGKE genetic mutations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DGKE cdna clone

Products by Pathway	Pathway Diagram
Effects Of PIP2 Hydrolysis Pathway antibodies	Effects Of PIP2 Hydrolysis Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Phosphatidylinositol Signaling System Pathway antibodies	Phosphatidylinositol Signaling System Pathway Diagram

Diseases associated with DGKE cdna clone

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>3 publications with DGKE and Kidney Diseases
Atypical hemolytic uremic syndrome Antibodies	>3 publications with DGKE and Atypical hemolytic uremic syndrome
Hematologic Diseases Antibodies	>2 publications with DGKE and Hematologic Diseases
Seizures Antibodies	>1 publications with DGKE and Seizures
Depressive Disorder Antibodies	>1 publications with DGKE and Depressive Disorder

Organs/Tissues associated with DGKE cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with DGKE and Kidney
Liver Antibodies	>1 publications with DGKE and Liver
Vascular Antibodies	>1 publications with DGKE and Vascular
Brain Antibodies	>1 publications with DGKE and Brain