Human DLX3 cDNA Clone Expression Plasmid – Cat# MBS1274914

DLX3 cDNA Clone – Distal-Less Homeobox 3 (Human)

Name: DLX3 cDNA Clone; Distal-Less Homeobox 3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274914
Price: 365 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274914

MBS1274914 is a cDNA clone targeting DLX3. More details

$365 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DLX3, cDNA Clone

Full Product Name

DLX3 cDNA Clone

Product Gene Name

DLX3 cdna clone

Sequence

atgagtggct ccttcgatcg caagctcagc agcatcctca ccgacatctc cagctccctt agctgccatg cgggctccaa ggactcgcct accctgcccg agtcttctgt cactgacctg ggctactaca gcgctcccca gcacgattac tactcgggcc agccctatgg ccagacggtg aacccctaca cctaccacca ccaattcaat ctcaatgggc ttgcaggcac gggcgcttac tcgcccaagt cggaatatac ctacggagcc tcctaccggc aatacggggc gtatcgggag cagccgctgc cagcccagga cccagtgtcg gtgaaggagg agccggaagc agaggtgcgc atggtgaatg ggaagcccaa gaaggtccga aagccgcgta caatctactc cagctaccag ctggccgccc tgcagcgccg cttccagaag gcccagtacc tggcgctgcc cgagcgcgcc gagctggccg cgcagctggg cctcacgcag acacaggtga aaatctggtt ccagaaccgc cgttccaagt tcaagaaact ctacaagaac ggggaggtgc cgctggagca cagtcccaat aacagtgatt ccatggcctg caactcacca ccatcacccg ccctctggga cacctcttcc cactccactc cggcccctgc ccgcagtcag ctgcccccgc cgctcccata cagtgcctcc cccagctacc tggacgaccc caccaactcc tggtatcacg cacagaacct gagtggaccc cacttacagc agcagccgcc tcagccagcc accctgcacc atgcctctcc cgggcccccg cccaaccctg gggctgtgta ctga

Molecular Weight

31,738 Da

OMIM

104510

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DLX3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DLX3. It may not necessarily be applicable to this product.

NCBI GI #

15214474

NCBI GeneID

1747

NCBI Accession #

BC012361

UniProt Secondary Accession #

B3KQL6

UniProt Related Accession #

O60479

NCBI Official Full Name

Homo sapiens distal-less homeobox 3, mRNA

NCBI Official Synonym Full Names

distal-less homeobox 3

NCBI Official Symbol

DLX3

NCBI Official Synonym Symbols

AI4; TDO

UniProt Protein Name

Homeobox protein DLX-3

Protein Family

Distal-less-like protein

UniProt Gene Name

DLX3

UniProt Entry Name

DLX3_HUMAN

NCBI Protein Information

homeobox protein DLX-3

NCBI Summary for DLX3

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]

UniProt Comments for DLX3

DLX3: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Defects in DLX3 are a cause of trichodentoosseous syndrome (TDO). TDO is an autosomal dominant syndrome characterized by enamel hypoplasia and hypocalcification with associated strikingly curly hair. Defects in DLX3 are the cause of amelogenesis imperfecta type 4 (AI4); also known as amelogenesis imperfecta hypomaturation-hypoplastic type with taurodontism. AI4 is an autosomal dominant defect of enamel formation associated with enlarged pulp chambers. Belongs to the distal-less homeobox family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 17q21

Molecular Function: transcription factor activity

Disease: Amelogenesis Imperfecta, Type Iv; Trichodentoosseous Syndrome

Research Articles on DLX3

1. Results suggest that Dlx3 is a novel target of PKA, and that PKA mediates BMP signaling during osteoblast differentiation, at least in part, by phosphorylating Dlx3 and modulating its stability and function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with DLX3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>12 publications with DLX3 and Neoplasms
Pregnancy Complications Antibodies	>5 publications with DLX3 and Pregnancy Complications
Carcinoma Antibodies	>4 publications with DLX3 and Carcinoma
Abnormalities, Drug-Induced Antibodies	>2 publications with DLX3 and Abnormalities, Drug-Induced
Fetal Death Antibodies	>2 publications with DLX3 and Fetal Death
Premature Birth Antibodies	>1 publications with DLX3 and Premature Birth
Hyperplasia Antibodies	>1 publications with DLX3 and Hyperplasia
Drug Toxicity Antibodies	>1 publications with DLX3 and Drug Toxicity
Cardiovascular Diseases Antibodies	>1 publications with DLX3 and Cardiovascular Diseases

Organs/Tissues associated with DLX3 cdna clone

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>23 publications with DLX3 and Placenta
Embryonic Tissue Antibodies	>20 publications with DLX3 and Embryonic Tissue
Mouth Antibodies	>14 publications with DLX3 and Mouth
Connective Tissue Antibodies	>12 publications with DLX3 and Connective Tissue
Brain Antibodies	>10 publications with DLX3 and Brain
Eye Antibodies	>3 publications with DLX3 and Eye
Heart Antibodies	>2 publications with DLX3 and Heart