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ECHS1 cDNA Clone – Enoyl Coenzyme A Hydratase, Short Chain, 1, Mitochondrial (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267978

MBS1267978 is a cDNA clone targeting ECHS1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ECHS1, cDNA Clone
Full Product Name
ECHS1 cDNA Clone
Product Gene Name
ECHS1 cdna clone
Sequence
atggccgccc tgcgtgtcct gctgtcctgc gtccgcggcc cgctgaggcc cccggttcgc tgtcccgcct ggcgtccctt cgcctcgggt gctaactttg agtacatcat cgcagaaaaa agagggaaga ataacaccgt ggggttgatc caactgaacc gccccaaggc cctcaatgca ctttgcgatg gcctgattga cgagctcaac caggccctga agatcttcga ggaggacccg gccgtggggg ccattgtcct caccggcggg gataaggcct ttgcagctgg agctgatatc aaggaaatgc agaacctgag tttccaggac tgttactcca gcaagttctt gaagcactgg gaccacctca cccaggtcaa gaagccagtc atcgctgctg tcaatggcta tgcctttggc gggggctgtg agcttgccat gatgtgtgat atcatctatg ccggtgagaa ggcccagttt gcacagccgg agatcttaat aggaaccatc ccaggtgcgg gcggcaccca gagactcacc cgtgctgttg ggaagtcgct ggcgatggag atggtcctca ccggtgaccg gatctcagcc caggacgcca agcaagcagg tcttgtcagc aagatttgtc ctgttgagac actggtggaa gaagccatcc agtgtgcaga aaaaattgcc agcaattcta aaattgtagt agcgatggcc aaagaatcag tgaatgcagc ttttgaaatg acattaacag aaggaagtaa gttggagaag aaactctttt attcaacctt tgccactgat gaccggaaag aagggatgac cgcgtttgtg gaaaagagaa aggccaactt caaagaccag tga
Molecular Weight
31,387 Da
OMIM
602292
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ECHS1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ECHS1. It may not necessarily be applicable to this product.

NCBI GI #
34783845
NCBI GeneID
1892
NCBI Accession #
BC008906
UniProt Secondary Accession #
O00739; Q5VWY1; Q96H54
UniProt Related Accession #
P30084
NCBI Official Full Name
Homo sapiens enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, mRNA
NCBI Official Synonym Full Names
enoyl-CoA hydratase, short chain 1
NCBI Official Symbol
ECHS1
NCBI Official Synonym Symbols
SCEH; ECHS1D
UniProt Protein Name
Enoyl-CoA hydratase, mitochondrial
UniProt Synonym Protein Names
Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase; SCEH
Protein Family
Enoyl-CoA hydratase
UniProt Gene Name
ECHS1
UniProt Synonym Gene Names
SCEH
UniProt Entry Name
ECHM_HUMAN
NCBI Protein Information
enoyl-CoA hydratase, mitochondrial

NCBI Summary for ECHS1

The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]
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UniProt Comments for ECHS1

ECHS1: Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Belongs to the enoyl-CoA hydratase/isomerase family.

Protein type: Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - tryptophan; EC 4.2.1.17; Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lyase; Carbohydrate Metabolism - butanoate; Secondary Metabolites Metabolism - limonene and pinene degradation; Mitochondrial

Chromosomal Location of Human Ortholog: 10q26.2-q26.3

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: enoyl-CoA hydratase activity; protein binding

Biological Process: fatty acid beta-oxidation

Disease: Mitochondrial Short-chain Enoyl-coa Hydratase 1 Deficiency
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Research Articles on ECHS1

1. These results suggested that ECHS1 may promote cell proliferation in hepatocellular carcinoma in an EGFR-dependent manner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ECHS1 cdna clone

 Products by Pathway  Pathway Diagram
 Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway antibodies  Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway Diagram
 Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway antibodies  Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway Diagram
 Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway antibodies  Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway Diagram

Diseases associated with ECHS1 cdna clone

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >6 publications with ECHS1 and Liver Diseases
 Fatty Liver Antibodies  >6 publications with ECHS1 and Fatty Liver
 Carcinoma, Hepatocellular Antibodies  >3 publications with ECHS1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >3 publications with ECHS1 and Liver Neoplasms
 Hepatitis Antibodies  >3 publications with ECHS1 and Hepatitis
 Inflammation Antibodies  >2 publications with ECHS1 and Inflammation
 Hyperplasia Antibodies  >2 publications with ECHS1 and Hyperplasia
 Obesity Antibodies  >2 publications with ECHS1 and Obesity
 Heart Diseases Antibodies  >1 publications with ECHS1 and Heart Diseases
 Cardiovascular Diseases Antibodies  >1 publications with ECHS1 and Cardiovascular Diseases

Organs/Tissues associated with ECHS1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with ECHS1 and Liver
 Testis Antibodies  >2 publications with ECHS1 and Testis
 Nerve Antibodies  >2 publications with ECHS1 and Nerve
 Brain Antibodies  >2 publications with ECHS1 and Brain
 Lymph Antibodies  >1 publications with ECHS1 and Lymph
 Ovary Antibodies  >1 publications with ECHS1 and Ovary
 Thyroid Antibodies  >1 publications with ECHS1 and Thyroid
 Lung Antibodies  >1 publications with ECHS1 and Lung
 Prostate Antibodies  >1 publications with ECHS1 and Prostate
 Skin Antibodies  >1 publications with ECHS1 and Skin
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