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EFTUD2 cDNA Clone – Elongation Factor Tu GTP Binding Domain Containing 2 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267916

MBS1267916 is a cDNA clone targeting EFTUD2. More details

$630 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EFTUD2, cDNA Clone
Full Product Name
EFTUD2 cDNA Clone
Product Gene Name
Sequence
atggataccg acttatatga tgagtttggg aattatattg gaccagagct tgattctgat gaagatgatg atgaattggg tagagagacc aaagatcttg atgagatgga tgatgatgac gacgacgatg acgtaggaga tcatgacgat gaccaccctg ggatggaggt ggtgctgcat gaggacaaga agtactaccc aacagccgag gaggtgtatg gtcctgaggt ggagaccata gttcaagagg aagacactca gcctctcaca gaacccatta ttaagccagt gaaaaccaag aaattcactc tgatggagca gacattacct gttacggtgt atgagatgga tttcttggcg gatctgatgg ataactcaga gctcatcaga aatgtgaccc tttgtggaca tctccaccat ggcaagacat gttttgtgga ttgtttaatt gaacagactc acccggaaat cagaaagcgc tatgaccaag atctgtgcta tactgacatc ctcttcacag agcaagagag aggtgtaggc atcaaaagca ctcctgtgac agtggtcttg ccagacacca aaggaaaatc ttatctcttc aatatcatgg acactccagg acatgtgaat ttctctgatg aggtcacagc tggcttgcgc atctcagatg gagtggtcct tttcattgat gctgctgagg gggtgatgct gaacacagag cggctgatca agcatgcggt gcaggagagg ctggcagtca ctgtgtgcat caacaagatt gaccggctga tcctggagct gaagctgcct ccaactgatg cttattacaa gctgcgccac attgtggatg aggtcaatgg attaataagc atgtattcca ctgatgagaa cctgatcctt tccccactcc tgggtaacgt ctgcttctcc agctcccagt acagcatctg cttcacgctg gtctcctttg ccaagatcta tgccgacacc tttggtgaca ttaattacca agaatttgct aaaagactct ggggtgacat ctacttcaac cctaagacgc gaaagttcac caaaaaggcc ccaactagca gctcccagag aagtttcgtg gagtttatct tggagcctct ttataagatc ctcgcccagg ttgtaggtga cgtggacacc agcctcccac ggaccctaga cgagcttggc atccacctga cgaaggagga gctgaagctg aacatccgcc ccttgctcag gctggtctgc aaaaagttct ttggcgagtt cacaggcttt gtggacatgt gtgtgcagca tatcccttct ccaaaggtgg gcgccaagcc caagattgag cacacctaca ccggtggtgt ggactccgac ctcggcgagg ctatgagtga ctgtgaccct gatggccccc tgatgtgcca cactactaag atgtacagca cagatgatgg agtccagttt cacgcctttg gccgggtgct gagtggcacc attcatgctg ggcagcctgt gaaggtactg ggggagaact acaccctgga ggatgaggaa gactcccaga tatgcaccgt gggccgcctt tggatctctg tggccaggta ccacatcgag gtgaaccgtg ttcctgctgg caactgggtt ctgattgaag gtgttgatca accaattgtg aagacagcaa ccataaccga accccgaggc aatgaggagg ctcagatttt ccgacccttg aagttcaata ccacatctgt tatcaagatt gctgtggagc cagtcaaccc ctcagagctg cccaagatgc ttgatggcct gcgcaaggtc aacaagagct atccatccct caccaccaag gtggaggagt ctggcgagca tgtgatcctg ggcactgggg agctctacct ggactgtgtg atgcatgatt tgcggaagat gtactcagag atagacatca aggtggctga cccagttgtc acgttttgtg agacggtggt ggaaacatcc tccctcaagt gctttgctga aacgcctaat aagaagaaca agatcaccat gattgctgag cctcttgaga agggcctggc agaggacata gagaatgagg tggtccagat tacgtggaac aggaagaagc tgggagagtt cttccagacc aagtacgatt gggatctgct ggctgcccgt tccatctggg cttttggccc tgatgcgact ggccccaaca ttctggtgga tgatactctg ccctctgagg tggacaaggc tcttcttggt tcagtgaagg acagcatcgt tcaaggtttc cagtggggaa ccagggaggg ccccctctgt gatgaattga ttcggaatgt caagtttaag atcctggatg cggtggttgc ccaggagccc ctgcaccggg gcgggggcca gatcatcccc acagccagga gagtcgtcta ctctgccttc ctcatggcta ctcctcgtct gatggagcct tactactttg tagaggtcca ggcccctgca gattgcgtct ctgcagttta taccgtcctg gccaggcgca gggggcacgt gactcaggat gcacccatcc caggctcccc tctgtacacc atcaaagctt ttatcccggc catcgactct tttggctttg agactgatct ccggactcac acccagggac aagccttttc tctgtctgtc ttccaccact ggcagattgt gcctggtgat cccctggaca agagcattgt catccgcccc ttggagccac agccagctcc tcacctggcc cgggaattca tgatcaaaac ccgccgtagg aagggcctca gtgaagatgt gagcatcagc aaattcttcg atgatcctat gttgctggaa cttgccaaac aggatgttgt gctcaattac cccatgtga
Molecular Weight
108,283 Da
OMIM
603892
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EFTUD2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EFTUD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens elongation factor Tu GTP binding domain containing 2, mRNA
NCBI Official Synonym Full Names
elongation factor Tu GTP binding domain containing 2
NCBI Official Symbol
EFTUD2
NCBI Official Synonym Symbols
MFDM; MFDGA; Snu114; Snrp116; SNRNP116; U5-116KD
UniProt Protein Name
116 kDa U5 small nuclear ribonucleoprotein component
UniProt Synonym Protein Names
Elongation factor Tu GTP-binding domain-containing protein 2; SNU114 homolog; hSNU114; U5 snRNP-specific protein, 116 kDa; U5-116 kDa
UniProt Gene Name
EFTUD2
UniProt Synonym Gene Names
KIAA0031; SNRP116; hSNU114; U5-116 kDa
UniProt Entry Name
U5S1_HUMAN
NCBI Protein Information
116 kDa U5 small nuclear ribonucleoprotein component

NCBI Summary for EFTUD2

This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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UniProt Comments for EFTUD2

EFTUD2: Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP. Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM). A rare syndrome characterized by progressive microcephaly, midface and malar hypoplasia, micrognathia, microtia, dysplastic ears, preauricular skin tags, significant developmental delay, and speech delay. Many patients have major sequelae, including choanal atresia that results in respiratory difficulties, conductive hearing loss, and cleft palate. Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA-binding; RNA splicing

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: Cajal body; cytoplasm; extracellular matrix; membrane; nuclear speck; nucleoplasm; spliceosome

Molecular Function: protein binding

Biological Process: mRNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing; translation

Disease: Mandibulofacial Dysostosis, Guion-almeida Type
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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