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EIF5 cDNA Clone – Eukaryotic Translation Initiation Factor 5 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275275

MBS1275275 is a cDNA clone targeting EIF5. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EIF5, cDNA Clone
Full Product Name
EIF5 cDNA Clone
Product Gene Name
EIF5 cdna clone
Sequence
atgtctgtca atgtcaaccg cagcgtgtca gaccagttct atcgctacaa gatgccccgt ctgattgcca aggttgaggg caaaggcaat ggaatcaaga cagttatagt caacatggtt gacgttgcaa aggcgcttaa tcggcctcca acgtatccca ccaaatattt tggttgtgag ctgggagcac agacccagtt tgatgttaag aatgaccgtt acattgtcaa tggatctcat gaggcgaata agctgcaaga catgttggat ggattcatta aaaaatttgt tctctgtcct gaatgtgaga atcctgaaac agatttgcat gtcaatccaa agaagcaaac aataggtaat tcttgtaaag cctgtggcta tcgaggcatg cttgacacac atcataaact ctgcacattc attctcaaaa acccacctga gaatagtgac agtggtacag gaaagaaaga aaaagaaaag aaaaacagaa agggcaaaga caaggaaaat ggctccgtat ccagcagtga gacaccacca ccaccaccac caccaaatga aattaatcct cctccacata caatggaaga agaggaggat gatgactggg gagaagatac aactgaggaa gctcaaaggc gtcgaatgga tgaaatcagt gaccatgcaa aagttctgac actcagtgat gatttggaaa gaacaattga ggagagggtc aatatcctct ttgattttgt taagaaaaag aaagaagagg gtgttattga ttcatctgac aaagaaatcg ttgctgaagc agaaagactg gatgtaaaag ccatgggccc tcttgttcta actgaagttc tttttaatga gaagattaga gaacagatta agaaatacag gcgccatttc ctacgatttt gtcacaacaa caaaaaagcc aaacggtacc ttcttcatgg tttggagtgt gtggtagcaa tgcatcaagc tcagcttatc tccaagattc cacatatctt gaaggagatg tacgatgcag accttttaga agaagaggtc atcatcagct ggtcggaaaa ggcctctaag aaatatgtct ccaaagaact tgccaaagag attcgtgtca aagcagaacc atttataaaa tggttgaagg aggcagagga agaatcttct ggtggcgaag aagaagatga agatgagaac attgaggtgg tgtattcgaa ggctgccagt gtaccgaaag ttgagactgt aaagtcagac aacaaggatg acgacatcga tattgatgcc atttaa
Molecular Weight
49,223 Da
OMIM
601710
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EIF5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF5. It may not necessarily be applicable to this product.

NCBI GI #
34193752
NCBI GeneID
1983
NCBI Accession #
BC032866
UniProt Secondary Accession #
Q53XB3; Q9H5N2; Q9UG48
UniProt Related Accession #
P55010
NCBI Official Full Name
Homo sapiens eukaryotic translation initiation factor 5, mRNA
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 5
NCBI Official Symbol
EIF5
NCBI Official Synonym Symbols
EIF-5; EIF-5A
UniProt Protein Name
Eukaryotic translation initiation factor 5
UniProt Gene Name
EIF5
UniProt Synonym Gene Names
eIF-5
UniProt Entry Name
IF5_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 5

NCBI Summary for EIF5

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]
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UniProt Comments for EIF5

EIF5: eukaryotic translation initiation factor 5. Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex.

Protein type: Translation; Translation initiation

Chromosomal Location of Human Ortholog: 14q32.32

Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; nucleus; plasma membrane

Molecular Function: GTPase activity; protein binding; translation factor activity, nucleic acid binding

Biological Process: regulation of translational initiation
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Research Articles on EIF5

1. it is eIF5-induced GTP hydrolysis and Pi release that irreversibly trap the 48S complex, and this complex is further stabilized by eIF5B and 60S joining.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with EIF5 cdna clone

 Products by Pathway  Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Ribosomal Scanning And Start Codon Recognition Pathway antibodies  Ribosomal Scanning And Start Codon Recognition Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 Translation Factors Pathway antibodies  Translation Factors Pathway Diagram

Diseases associated with EIF5 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with EIF5 and Neoplasms
 Carcinoma Antibodies  >4 publications with EIF5 and Carcinoma
 Adenocarcinoma Antibodies  >2 publications with EIF5 and Adenocarcinoma
 Weight Loss Antibodies  >1 publications with EIF5 and Weight Loss
 Lung Neoplasms Antibodies  >1 publications with EIF5 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with EIF5 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with EIF5 and Liver Diseases
 Neoplasms, Experimental Antibodies  >1 publications with EIF5 and Neoplasms, Experimental
 Lung Diseases Antibodies  >1 publications with EIF5 and Lung Diseases
 Liver Neoplasms Antibodies  >1 publications with EIF5 and Liver Neoplasms

Organs/Tissues associated with EIF5 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with EIF5 and Blood
 Liver Antibodies  >2 publications with EIF5 and Liver
 Lymph Node Antibodies  >1 publications with EIF5 and Lymph Node
 Muscle Antibodies  >1 publications with EIF5 and Muscle
 Lung Antibodies  >1 publications with EIF5 and Lung
 Kidney Antibodies  >1 publications with EIF5 and Kidney
 Brain Antibodies  >1 publications with EIF5 and Brain
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