Human EXOC6 cDNA Clone Expression Plasmid – Cat# MBS1274285

EXOC6 cDNA Clone – Exocyst Complex Component 6 (Human)

Name: EXOC6 cDNA Clone; Exocyst Complex Component 6; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274285
Price: 900 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274285

MBS1274285 is a cDNA clone targeting EXOC6. More details

$900 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EXOC6, cDNA Clone

Full Product Name

EXOC6 cDNA Clone

Product Gene Name

EXOC6 cdna clone

Sequence

atggcggaga acagcgagag tctgggcacc gtccccgagc acgagcggat cttgcaggag atcgagagca ccgacaccgc ctgtgtgggg cccaccctcc ggtctgtgta tgatgaccaa ccaaatgcgc acaagaagtt tatggaaaag ttagatgctt gtatccgtaa tcatgacaag gaaattgaaa agatgtgtaa ttttcatcat cagggttttg tagatgctat tacagaactc cttaaagtaa ggactgatgc agaaaaactg aaggtgcaag ttactgatac caaccgaagg tttcaagatg ctggaaaaga ggtgatagtc cacacagaag atatcattcg atgtagaatt cagcagagaa atattacaac tgtagtagaa aaattgcagt tatgccttcc tgtgctagaa atgtacagta agctgaaaga acagatgagt gccaaaaggt actattctgc cctaaaaact atggaacaat tagagaatgt gtactttccc tgggttagtc aataccggtt ttgtcagctc atgatagaaa atcttcccaa actccgtgag gatattaaag aaatctccat gtctgatctc aaagactttt tggaaagtat tcgaaaacat tctgacaaaa taggtgaaac agcaatgaaa caggcacagc atcagaaaac cttcagtgtt tctctgcaga aacaaaataa aatgaaattt gggaaaaata tgtatataaa tcgtgataga attccagagg aaaggaatga aactgtattg aaacattcac ttgaagaaga ggatgagaat gaagaagaga tcttaactgt tcaggatctt gttgattttt cccctgttta tcgatgtttg cacatttatt ctgttttggg tgacgaggaa acatttgaaa actattatcg aaaacaaaga aagaaacaag caagactggt attgcaaccc cagtcgaata tgcatgaaac agttgatggc tatagaagat atttcactca aattgtaggg ttctttgtgg tagaagatca cattttacat gtgacccaag gattagtaac cagggcatac actgatgaac tttggaacat ggccctctca aagataattg ctgtccttag agctcattca tcctattgca ctgatcctga tcttgttctg gagctgaaga atcttattgt aatatttgca gatactttac agggttatgg ttttccagtg aaccgacttt ttgacctttt atttgaaata agagaccaat acaatgaaac actgcttaag aaatgggctg gagttttcag ggacattttt gaagaagata attacagccc catccctgtt gtcaatgaag aagaatataa aattgtcatc agcaaatttc cctttcaaga tccagacctt gaaaagcagt ctttcccaaa gaaattcccc atgtctcagt cagtgcctca tatttacatt caagttaaag aatttattta tgccagcctt aaattttcag agtcactaca ccggagctca acagaaatag acgatatgct tagaaaatca acaaatctgc tgctgaccag aactttgagt agctgtttac tgaaccttat tagaaaacct catataggtt tgacagagct ggtacaaatc atcataaaca caacacacct ggagcaagct tgtaaatatc ttgaggactt tataactaac attacaaata tttcccaaga aactgttcat actacaagac tttatggact ttctactttc aaggatgctc gacatgcagc agaaggagaa atatatacca aactgaatca aaaaattgat gaatttgttc agcttgctga ttatgactgg acaatgtctg agccagatgg aagagctagt ggttatttaa tggaccttat aaattttttg agaagcatct ttcaagtgtt tactcatttg cctgggaaag ttgctcagac agcttgcatg tcagcctgcc agcatctgtc aacatcctta atgcagatgc tactggacag tgagttaaaa caaataagca tgggagctgt tcagcagttt aacttagatg tcatacagtg tgaattgttt gccagctctg agcctgtgcc aggattccag ggggataccc tgcagctagc attcattgac ctcagacaac tccttgacct gtttatggtt tgggattggt ctacttacct agctgattat gggcagccag cttctaagta ccttcgggtg aatccaaaca cagcccttac tcttttggag aagatgaagg atactagcaa aaagaacaat atatttgctc agttcgggaa gaatgatcga gacaaacaga agttgataga gacagtcgtg aaacagctga gaagtttggt gaatggtatg tcccagcaca tgtag

Molecular Weight

93,407 Da

OMIM

609672

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EXOC6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EXOC6. It may not necessarily be applicable to this product.

NCBI GI #

34783238

NCBI GeneID

54536

NCBI Accession #

BC028395

UniProt Secondary Accession #

Q5VXH8; Q9NZ24; E9PHI3

UniProt Related Accession #

Q8TAG9

NCBI Official Full Name

Homo sapiens exocyst complex component 6, mRNA

NCBI Official Synonym Full Names

exocyst complex component 6

NCBI Official Symbol

EXOC6

NCBI Official Synonym Symbols

SEC15; EXOC6A; SEC15L; Sec15p; SEC15L1; SEC15L3

UniProt Protein Name

Exocyst complex component 6

UniProt Synonym Protein Names

Exocyst complex component Sec15A; SEC15-like protein 1

Protein Family

Exocyst complex component

UniProt Gene Name

EXOC6

UniProt Synonym Gene Names

SEC15A; SEC15L; SEC15L1

UniProt Entry Name

EXOC6_HUMAN

NCBI Protein Information

exocyst complex component 6

NCBI Summary for EXOC6

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016]

UniProt Comments for EXOC6

EXOC6: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC15 family.

Chromosomal Location of Human Ortholog: 10q23.33

Cellular Component: cytosol; plasma membrane

Molecular Function: protein binding

Research Articles on EXOC6

1. NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by triggering the switch in binding specificity of Rabin8 from PS to Sec15.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with EXOC6 cdna clone

Products by Pathway	Pathway Diagram
Arf6 Trafficking Events Pathway antibodies	Arf6 Trafficking Events Pathway Diagram
Insulin Pathway antibodies	Insulin Pathway Diagram
Insulin Processing Pathway antibodies	Insulin Processing Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies	Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram

Diseases associated with EXOC6 cdna clone

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with EXOC6 and Breast Neoplasms
Brain Diseases Antibodies	>1 publications with EXOC6 and Brain Diseases
Neoplasms Antibodies	>1 publications with EXOC6 and Neoplasms

Organs/Tissues associated with EXOC6 cdna clone

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>1 publications with EXOC6 and Nerve
Eye Antibodies	>1 publications with EXOC6 and Eye
Brain Antibodies	>1 publications with EXOC6 and Brain