Human FCN1 cDNA Clone Expression Plasmid – Cat# MBS1268659

FCN1 cDNA Clone – Ficolin (Collagen/Fibrinogen Domain Containing) 1 (Human)

Name: FCN1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268659
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268659

MBS1268659 is a cDNA clone targeting FCN1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FCN1, cDNA Clone

Full Product Name

FCN1 cDNA Clone

Product Gene Name

FCN1 cdna clone

Sequence

atggagctga gtggagccac catggcccgg ggtctcgctg tcctgctagt cttgttcctg catatcaaga acctgcctgc ccaggctgcg gacacatgtc cagaggtgaa ggtggtgggc ctggagggct ctgacaagct caccattctc cgaggctgcc cggggctgcc cggggcccca gggccaaagg gagaggcagg tgtcattgga gagagaggag aacgcggtct ccctggagcc cctggaaagg caggaccagt ggggcccaaa ggagaccgag gagagaaggg gatgcgtgga gagaaaggag acgctgggca gtctcagtcg tgtgcgacag gcccacgcaa ctgcaaggac ctgctagacc gggggtattt cctgagcggc tggcacacca tctacctgcc cgactgccgg cccctgactg tgctctgtga catggacacg gacggagggg gctggaccgt tttccagcgg aggatggatg gctctgtgga cttctatcgg gactgggccg catacaagca gggcttcggc agtcagctgg gggagttctg gctggggaac gacaacatcc acgccctgac tgcccaggga agcagcgagc tccgtgtaga cctggtggac tttgagggca accaccagtt tgctaagtac aaatcattca aggtggctga cgaggcagag aagtacaagc tggtactggg agcctttgtc gggggcagtg cgggtaattc tctaacgggc cacaacaaca acttcttctc caccaaagac caagacaatg atgtgagttc ttcgaattgt gctgagaagt tccagggagc ctggtggtac gccgactgtc atgcttcaaa cctcaatggt ctctacctca tgggacccca tgagagctat gccaatggta tcaactggag tgcggcgaag gggtacaaat atagctacaa ggtgtcagag atgaaggtgc ggcccgccta g

Molecular Weight

35,078 Da

OMIM

601252

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FCN1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FCN1. It may not necessarily be applicable to this product.

NCBI GI #

18088848

NCBI GeneID

2219

NCBI Accession #

BC020635

UniProt Secondary Accession #

Q5VYV5; Q92596

UniProt Related Accession #

O00602

NCBI Official Full Name

Homo sapiens ficolin (collagen/fibrinogen domain containing) 1, mRNA

NCBI Official Synonym Full Names

ficolin 1

NCBI Official Symbol

FCN1

NCBI Official Synonym Symbols

FCNM

UniProt Protein Name

Ficolin-1

UniProt Synonym Protein Names

Collagen/fibrinogen domain-containing protein 1; Ficolin-A; Ficolin-alpha; M-ficolin

Protein Family

Ficolin

UniProt Gene Name

FCN1

UniProt Synonym Gene Names

FCNM

UniProt Entry Name

FCN1_HUMAN

NCBI Protein Information

ficolin-1

NCBI Summary for FCN1

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

UniProt Comments for FCN1

FCN1: Complement-activating lectin and pattern recognition receptor. Binds GlcNAc. Binds preferentially to 9-O-acetylated 2- 6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. Belongs to the ficolin lectin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular region; extrinsic to external side of plasma membrane

Molecular Function: G-protein-coupled receptor binding; pattern recognition receptor activity; protein binding; serine-type endopeptidase activity; sialic acid binding

Biological Process: cell surface pattern recognition receptor signaling pathway; complement activation; complement activation, lectin pathway; G-protein coupled receptor protein signaling pathway; negative regulation of virion penetration into host cell; recognition of apoptotic cell

Research Articles on FCN1

1. Data indicate differences in the plasma concentrations of collectin liver 1 and collectin kidney 1, M-ficolin and H-ficol in systemic lupus erythematosus (SLE) patients compared to a group of healthy controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with FCN1 cdna clone

Disease Name	Pubmed Publications
Gastrointestinal Diseases Antibodies	>1 publications with FCN1 and Gastrointestinal Diseases
Fatigue Antibodies	>1 publications with FCN1 and Fatigue
Inflammatory Bowel Diseases Antibodies	>1 publications with FCN1 and Inflammatory Bowel Diseases

Organs/Tissues associated with FCN1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>9 publications with FCN1 and Blood
Bone Antibodies	>1 publications with FCN1 and Bone
Brain Antibodies	>1 publications with FCN1 and Brain
Bone Marrow Antibodies	>1 publications with FCN1 and Bone Marrow
Intestine Antibodies	>1 publications with FCN1 and Intestine
Lung Antibodies	>1 publications with FCN1 and Lung