Human FEZ1 cDNA Clone Expression Plasmid – Cat# MBS1273455

FEZ1 cDNA Clone – Fasciculation and Elongation Protein Zeta 1 (Zygin I) (Human)

Name: FEZ1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273455
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273455

MBS1273455 is a cDNA clone targeting FEZ1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FEZ1, cDNA Clone

Full Product Name

FEZ1 cDNA Clone

Product Gene Name

FEZ1 cdna clone

Sequence

atggaggccc cactggtgag tctggatgaa gagtttgagg accttcgacc ctcctgctcg gaggacccgg aggagaagcc ccagtgtttc tatggttcat ctccccacca tctcgaggac ccctccctct ccgagcttga gaatttttct tccgaaataa tcagcttcaa gtccatggag gacctcgtaa atgaatttga tgagaagctc aatgtctgct ttcggaacta caacgccaag accgagaacc tagctcccgt gaagaaccag ttacagatcc aagaggagga ggagaccctt caggacgagg aggtttggga tgctctgaca gacaattaca tcccttcact ctcagaagac tggagggatc caaacatcga ggctctgaat ggcaactgct ctgacactga gatccatgag aaagaagagg aagagttcaa tgagaagagt gaaaatgatt ccggtatcaa cgaggagcct ctgctcacag cagatcaggt aattgaggag attgaggaaa tgatgcagaa ctccccagac cctgaggaag aagaggaggt tctggaagaa gaggatggag gagaaacttc ctcccaggca gactcggtcc tcctgcagga gatgcaggca ttgacacaga ccttcaacaa caactggtcc tatgaagggc tgaggcacat gtctgggtct gagctgaccg agctgctgga ccaggtggag ggtgccatcc gtgacttctc ggaggagctg gtgcagcagc tggcccgccg ggacgagctg gagtttgaga aggaagtgaa gaactccttt atcacggtgc ttattgaggt tcagaacaag cagaaggagc agcgagaact gatgaaaaag aggcggaaag agaaagggct gagcctgcag agcagccgga tagagaaggg aaaccagatg cctctcaagc gcttcagcat ggaaggcatc tccaacattc tgcagagtgg catccgccag acctttggct cctcaggaac tgacaaacag tatctgaaca cagtcattcc ttacgagaag aaagcctctc ctccctcagt ggaagacctg cagatgctga caaacattct ctttgccatg aaggaggata atgagaaggt gcctactttg ctaacggact acattttaaa agtgctctgc cctacctaa

Molecular Weight

12,074 Da

OMIM

604825

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FEZ1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FEZ1. It may not necessarily be applicable to this product.

NCBI GI #

16306950

NCBI GeneID

9638

NCBI Accession #

BC009545

UniProt Secondary Accession #

O00679; O00728; Q6IBI7

UniProt Related Accession #

Q99689

NCBI Official Full Name

Homo sapiens fasciculation and elongation protein zeta 1 (zygin I), mRNA

NCBI Official Synonym Full Names

fasciculation and elongation protein zeta 1

NCBI Official Symbol

FEZ1

NCBI Official Synonym Symbols

UNC-76

UniProt Protein Name

Fasciculation and elongation protein zeta-1

UniProt Synonym Protein Names

Zygin I; Zygin-1

Protein Family

Fasciculation and elongation protein

UniProt Gene Name

FEZ1

UniProt Entry Name

FEZ1_HUMAN

NCBI Protein Information

fasciculation and elongation protein zeta-1

NCBI Summary for FEZ1

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for FEZ1

FEZ1: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: cytoplasm; Golgi apparatus; microtubule cytoskeleton

Molecular Function: protein binding

Biological Process: axon guidance; cell adhesion; nervous system development

Research Articles on FEZ1

1. FEZ1 promotes HIV-1 infection in non-neuronal cells via direct binding to the capsid and kinesin-1 to move the virus into the cell nucleus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with FEZ1 cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with FEZ1 and Nervous System Diseases
Urinary Bladder Neoplasms Antibodies	>4 publications with FEZ1 and Urinary Bladder Neoplasms
Brain Diseases Antibodies	>3 publications with FEZ1 and Brain Diseases
Neoplasms, Experimental Antibodies	>3 publications with FEZ1 and Neoplasms, Experimental
Carcinoma, Squamous Cell Antibodies	>3 publications with FEZ1 and Carcinoma, Squamous Cell
Congenital Abnormalities Antibodies	>2 publications with FEZ1 and Congenital Abnormalities
Abnormalities, Multiple Antibodies	>2 publications with FEZ1 and Abnormalities, Multiple
Neoplasm Metastasis Antibodies	>1 publications with FEZ1 and Neoplasm Metastasis
Neural Tube Defects Antibodies	>1 publications with FEZ1 and Neural Tube Defects
Carcinoma, Hepatocellular Antibodies	>1 publications with FEZ1 and Carcinoma, Hepatocellular

Organs/Tissues associated with FEZ1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>35 publications with FEZ1 and Brain
Kidney Antibodies	>6 publications with FEZ1 and Kidney
Embryonic Tissue Antibodies	>6 publications with FEZ1 and Embryonic Tissue
Lung Antibodies	>2 publications with FEZ1 and Lung
Testis Antibodies	>2 publications with FEZ1 and Testis
Mouth Antibodies	>1 publications with FEZ1 and Mouth