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FOS cDNA Clone – V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270804

MBS1270804 is a cDNA clone targeting FOS. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FOS, cDNA Clone
Full Product Name
FOS cDNA Clone
Product Gene Name
FOS cdna clone
Sequence
atgatgttct cgggcttcaa cgcagactac gaggcgtcat cctcccgctg cagcagcgcg tccccggccg gggatagcct ctcttactac cactcacccg cagactcctt ctccagcatg ggctcgcctg tcaacgcgca ggacttctgc acggacctgg ccgtctccag tgccaacttc attcccacgg tcactgccat ctcgaccagt ccggacctgc agtggctggt gcagcccgcc ctcgtctcct ctgtggcccc atcgcagacc agagcccctc accctttcgg agtccccgcc ccctccgctg gggcttactc cagggctggc gttgtgaaga ccatgacagg aggccgagcg cagagcattg gcaggagggg caaggtggaa cagttatctc cagaagaaga agagaaaagg agaatccgaa gggaaaggaa taagatggct gcagccaaat gccgcaaccg gaggagggag ctgactgata cactccaagc ggagacagac caactagaag atgagaagtc tgctttgcag accgagattg ccaacctgct gaaggagaag gaaaaactag agttcatcct ggcagctcac cgacctgcct gcaagatccc tgatgacctg ggcttcccag aagagatgtc tgtggcttcc cttgatctga ctgggggcct gccagaggtt gccaccccgg agtctgagga ggccttcacc ctgcctctcc tcaatgaccc tgagcccaag ccctcagtgg aacctgtcaa gagcatcagc agcatggagc tgaagaccga gccctttgat gacttcctgt tcccagcatc atccaggccc agtggctctg agacagcccg ctccgtgcca gacatggacc tatctgggtc cttctatgca gcagactggg agcctctgca cagtggctcc ctggggatgg ggcccatggc cacagagctg gagcccctgt gcactccggt ggtcacctgt actcccagct gcactgctta cacgtcttcc ttcgtcttca cctaccccga ggctgactcc ttccccagct gtgcagctgc ccaccgcaag ggcagcagca gcaatgagcc ttcctctgac tcgctcagct cacccacgct gctggccctg tga
Molecular Weight
36,301 Da
OMIM
164810
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FOS cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FOS. It may not necessarily be applicable to this product.

NCBI GI #
33872858
NCBI GeneID
2353
NCBI Accession #
BC004490
UniProt Secondary Accession #
P18849; A8K4E2; B4DQ65
UniProt Related Accession #
P01100
NCBI Official Full Name
Homo sapiens v-fos FBJ murine osteosarcoma viral oncogene homolog, mRNA
NCBI Official Synonym Full Names
Fos proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol
FOS
NCBI Official Synonym Symbols
p55; AP-1; C-FOS
UniProt Protein Name
Proto-oncogene c-Fos
UniProt Synonym Protein Names
Cellular oncogene fos; G0/G1 switch regulatory protein 7
Protein Family
Proto-oncogene
UniProt Gene Name
FOS
UniProt Synonym Gene Names
G0S7
UniProt Entry Name
FOS_HUMAN
NCBI Protein Information
proto-oncogene c-Fos

NCBI Summary for FOS

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
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UniProt Comments for FOS

Fos: a proto-oncogenic transcription factor of the bZIP family. Dimerizes with proteins of the JUN family, thereby forming the transcription factor complex AP-1. FOS proteins function as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of FOS has also been associated with apoptotic cell death. Expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Oncoprotein; Transcription factor

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; transcription factor activity; transcription factor binding

Biological Process: DNA methylation; inflammatory response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription factor activity; regulation of transcription from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway
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Research Articles on FOS

1. A novel AP-1 binding site at -1363 bp of the human TF promoter region was identified.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FOS cdna clone

 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies  Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram

Diseases associated with FOS cdna clone

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2578 publications with FOS and Nervous System Diseases
 Pain Antibodies  >1255 publications with FOS and Pain
 Drug Toxicity Antibodies  >897 publications with FOS and Drug Toxicity
 Inflammation Antibodies  >878 publications with FOS and Inflammation
 Necrosis Antibodies  >688 publications with FOS and Necrosis
 Epilepsy Antibodies  >481 publications with FOS and Epilepsy
 Seizures Antibodies  >476 publications with FOS and Seizures
 Liver Diseases Antibodies  >348 publications with FOS and Liver Diseases
 Hypertension Antibodies  >342 publications with FOS and Hypertension
 Heart Diseases Antibodies  >332 publications with FOS and Heart Diseases
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