Human FPR1 cDNA Clone Expression Plasmid – Cat# MBS1269918

FPR1 cDNA Clone – Formyl Peptide Receptor 1 (Human)

Name: FPR1 cDNA Clone; Formyl Peptide Receptor 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269918
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269918

MBS1269918 is a cDNA clone targeting FPR1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FPR1, cDNA Clone

Full Product Name

FPR1 cDNA Clone

Product Gene Name

FPR1 cdna clone

Sequence

atggagacaa attcctctct ccccacgaac atctctggag ggacacctgc tgtatctgct ggctatctct tcctggatat catcacttat ctggtatttg cagtcacctt tgtcctcggg gtcctgggca acgggcttgt gatctgggtg gctggattcc ggatgacaca cacagtcacc accatcagtt acctgaacct ggccgtggct gacttctgtt tcacctccac tttgccattc ttcatggtca ggaaggccat gggaggacat tggcctttcg gctggttcct gtgcaaattc gtctttacca tagtggacat caacttgttc ggaagtgtct tcctgatcgc cctcattgct ctggaccgct gtgtttgcgt cctgcatcca gtctggaccc agaaccaccg caccgtgagc ctggccaaga aggtgatcat tgggccctgg gtgatggctc tgctcctcac attgccagtt atcattcgtg tgactacagt acctggtaaa acggggacag tagcctgcac ttttaacttt tcgccctgga ccaacgaccc taaagagagg ataaatgtgg ccgttgccat gttgacggtg agaggcatca tccggttcat cattggcttc agcgcaccca tgtccatcgt tgctgtcagt tatgggctta ttgccaccaa gatccacaag caaggcttga ttaagtccag tcgtccctta cgggtcctct cctttgtcgc agcagccttt tttctctgct ggtccccata tcaggtggtg gcccttatag ccacagtcag aatccgtgag ttattgcaag gcatgtacaa agaaattggt attgcagtgg atgtgacaag tgccctggcc ttcttcaaca gctgcctcaa ccccatgctc tatgtcttca tgggccagga cttccgggag aggctgatcc acgcccttcc cgccagtctg gagagggccc tgaccgagga ctcaacccaa actagtgaca cagctaccaa ttctacttta ccttctgcag aggtggagtt acaggcaaag tga

Molecular Weight

38,446 Da

OMIM

136537

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FPR1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FPR1. It may not necessarily be applicable to this product.

NCBI GI #

13529064

NCBI GeneID

2357

NCBI Accession #

BC005315

UniProt Secondary Accession #

Q14939; Q7Z6A4; Q86U52; Q9NS48

UniProt Related Accession #

P21462

NCBI Official Full Name

Homo sapiens formyl peptide receptor 1, mRNA

NCBI Official Synonym Full Names

formyl peptide receptor 1

NCBI Official Symbol

FPR1

NCBI Official Synonym Symbols

FPR; FMLP

UniProt Protein Name

fMet-Leu-Phe receptor

UniProt Synonym Protein Names

N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor

Protein Family

FK506-binding protein

UniProt Gene Name

FPR1

UniProt Synonym Gene Names

fMLP receptor; FPR

UniProt Entry Name

FPR1_HUMAN

NCBI Protein Information

fMet-Leu-Phe receptor

NCBI Summary for FPR1

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

UniProt Comments for FPR1

FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Motility/polarity/chemotaxis; GPCR, family 1

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: endosome; plasma membrane

Molecular Function: N-formyl peptide receptor activity; protein binding; receptor activity

Biological Process: activation of MAPK activity; cell motility; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); nitric oxide mediated signal transduction; signal transduction

Research Articles on FPR1

1. FAM19A4 is a novel ligand of formyl peptide receptor 1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FPR1 cdna clone

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies	Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with FPR1 cdna clone

Disease Name	Pubmed Publications
Inflammation Antibodies	>55 publications with FPR1 and Inflammation
Cardiovascular Diseases Antibodies	>6 publications with FPR1 and Cardiovascular Diseases
Necrosis Antibodies	>6 publications with FPR1 and Necrosis
Nervous System Diseases Antibodies	>6 publications with FPR1 and Nervous System Diseases
Vascular Diseases Antibodies	>4 publications with FPR1 and Vascular Diseases
Drug Toxicity Antibodies	>4 publications with FPR1 and Drug Toxicity
Liver Diseases Antibodies	>3 publications with FPR1 and Liver Diseases
Pain Antibodies	>3 publications with FPR1 and Pain
Lung Diseases Antibodies	>3 publications with FPR1 and Lung Diseases
Asthma Antibodies	>3 publications with FPR1 and Asthma

Organs/Tissues associated with FPR1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>62 publications with FPR1 and Blood
Brain Antibodies	>8 publications with FPR1 and Brain
Lung Antibodies	>8 publications with FPR1 and Lung
Intestine Antibodies	>6 publications with FPR1 and Intestine
Bone Marrow Antibodies	>6 publications with FPR1 and Bone Marrow
Kidney Antibodies	>5 publications with FPR1 and Kidney
Heart Antibodies	>4 publications with FPR1 and Heart
Eye Antibodies	>4 publications with FPR1 and Eye
Stomach Antibodies	>2 publications with FPR1 and Stomach
Spleen Antibodies	>2 publications with FPR1 and Spleen