Human GABRA6 cDNA Clone Expression Plasmid – Cat# MBS1268176

GABRA6 cDNA Clone – Gamma-Aminobutyric Acid (GABA) A Receptor, Alpha 6 (Human)

Name: GABRA6 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268176
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268176

MBS1268176 is a cDNA clone targeting GABRA6. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GABRA6, cDNA Clone

Full Product Name

GABRA6 cDNA Clone

Product Gene Name

GABRA6 cdna clone

Sequence

ATGGCGTCGT CTCTGCCCTG GCTGTGCATT ATTCTGTGGC TAGAAAATGC CCTAGGGAAA CTCGAAGTTG AAGGCAACTT CTACTCAGAA AACGTCAGTC GGATCCTGGA CAACTTGCTT GAAGGCTATG ACAATCGGCT GCGGCCGGGA TTTGGAGGTG CTGTCACTGA AGTCAAAACA GACATTTATG TGACCAGTTT TGGGCCCGTG TCAGATGTGG AGATGGAGTA TACGATGGAT GTTTTTTTCC GCCAGACCTG GACTGATGAG AGGTTGAAGT TTGGGGGGCC AACTGAGATT CTGAGTCTGA ATAATTTGAT GGTCAGTAAA ATCTGGACGC CTGACACCTT TTTCAGAAAT GGTAAAAAGT CCATTGCTCA CAACATGACA ACTCCTAATA AACTCTTCAG AATAATGCAG AATGGAACCA TTTTATACAC CATGAGGCTT ACCATCAATG CTGACTGTCC CATGAGGCTG GTTAACTTTC CTATGGATGG GCATGCTTGT CCACTCAAGT TTGGGAGCTA TGCTTATCCC AAAAGTGAAA TCATATATAC GTGGAAAAAA GGACCACTTT ACTCAGTAGA AGTCCCAGAA GAATCTTCAA GCCTTCTCCA GTATGATCTG ATTGGACAAA CAGTATCTAG TGAGACAATT AAATCTAACA CAGGTGAATA CGTTATAATG ACAGTTTACT TCCACTTGCA AAGGAAGATG GGCTACTTCA TGATACAGAT ATACACTCCT TGCATTATGA CAGTCATTCT TTCCCAGGTG TCTTTCTGGA TTAATAAGGA GTCCGTCCCA GCAAGAACTG TTTTTGGGAT CACCACTGTT TTAACTATGA CCACTTTGAG CATCAGTGCC CGGCACTCTT TGCCAAAAGT GTCATATGCC ACTGCCATGG ATTGGTTCAT AGCTGTTTGC TTTGCATTCG TCTTCTCTGC TCTTATCGAG TTCGCAGCTG TCAACTACTT TACCAATCTT CAGACACAGA AGGCCAAAAG GAAGGCACAG TTTGCAGCCC CACCCACAGT GACAATATCA AAAGCTACTG AACCTTTGGA AGCTGAGATT GTTTTGCATC CTGACTCCAA ATATCATCTG AAGAAAAGGA TCACTTCTCT GTCTTTGCCA ATAGTTTCAT CTTCCGAGGC CAATAAAGTG CTCACGAGAG CGCCCATCTT ACAATCAACA CCTGTCACAC CCCCACCACT CTCGCCAGCC TTTGGAGGCA CCAGTAAAAT AGACCAGTAT TCTCGAATTC TCTTCCCAGT TGCATTTGCA GGATTCAACC TTGTGTACTG GGTAGTTTAT CTTTCCAAAG ATACAATGGA AGTGAGTAGC AGTGTTGAAT AG

Molecular Weight

51,024 Da

OMIM

137143

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GABRA6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GABRA6. It may not necessarily be applicable to this product.

NCBI GI #

109731536

NCBI GeneID

2559

NCBI Accession #

BC096241

UniProt Secondary Accession #

Q4VAV2; A8K096

UniProt Related Accession #

Q16445

NCBI Official Full Name

Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 6, mRNA

NCBI Official Synonym Full Names

gamma-aminobutyric acid type A receptor alpha6 subunit

NCBI Official Symbol

GABRA6

UniProt Protein Name

Gamma-aminobutyric acid receptor subunit alpha-6

UniProt Synonym Protein Names

GABA(A) receptor subunit alpha-6

Protein Family

Gamma-aminobutyric acid receptor

UniProt Gene Name

GABRA6

UniProt Entry Name

GBRA6_HUMAN

NCBI Protein Information

gamma-aminobutyric acid receptor subunit alpha-6

NCBI Summary for GABRA6

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for GABRA6

GABRA6: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Channel, chloride; Membrane protein, integral; Transporter, ion channel

Chromosomal Location of Human Ortholog: 5q34

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: benzodiazepine receptor activity; GABA-A receptor activity

Biological Process: signal transduction; transport

Research Articles on GABRA6

1. TMEM132D, COMT and GABRA6 gene polymorphisms may influence susceptibility to panic disorder(PD) and major depressive disorder(MDD)in Japanese adults; these variants may increase vulnerability to PD by modulating oligodendrocytes and GABA and dopaminergic functions in related brain regions, altering neuronal processing of anxiety-related emotional signals

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GABRA6 cdna clone

Products by Pathway	Pathway Diagram
GABA A Receptor Activation Pathway antibodies	GABA A Receptor Activation Pathway Diagram
GABA Receptor Activation Pathway antibodies	GABA Receptor Activation Pathway Diagram
GABAergic Synapse Pathway antibodies	GABAergic Synapse Pathway Diagram
GABAergic Synapse Pathway antibodies	GABAergic Synapse Pathway Diagram
Ion Channel Transport Pathway antibodies	Ion Channel Transport Pathway Diagram
Ligand-gated Ion Channel Transport Pathway antibodies	Ligand-gated Ion Channel Transport Pathway Diagram
Morphine Addiction Pathway antibodies	Morphine Addiction Pathway Diagram
Morphine Addiction Pathway antibodies	Morphine Addiction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with GABRA6 cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>13 publications with GABRA6 and Nervous System Diseases
Brain Diseases Antibodies	>12 publications with GABRA6 and Brain Diseases
Central Nervous System Diseases Antibodies	>9 publications with GABRA6 and Central Nervous System Diseases
Epilepsy Antibodies	>7 publications with GABRA6 and Epilepsy
Anxiety Disorders Antibodies	>6 publications with GABRA6 and Anxiety Disorders
Seizures Antibodies	>6 publications with GABRA6 and Seizures
Schizophrenia Antibodies	>4 publications with GABRA6 and Schizophrenia
Ataxia Antibodies	>3 publications with GABRA6 and Ataxia
Pain Antibodies	>2 publications with GABRA6 and Pain
Unconsciousness Antibodies	>1 publications with GABRA6 and Unconsciousness

Organs/Tissues associated with GABRA6 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>43 publications with GABRA6 and Brain
Muscle Antibodies	>1 publications with GABRA6 and Muscle