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GBP2 cDNA Clone – Guanylate Binding Protein 2, Interferon-Inducible (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269072

MBS1269072 is a cDNA clone targeting GBP2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GBP2, cDNA Clone
Full Product Name
GBP2 cDNA Clone
Product Gene Name
GBP2 cdna clone
Sequence
atggctccag agatcaactt gccgggccca atgagcctca ttgataacac taaagggcag ctggtggtga atccagaagc tctgaagatc ctatctgcaa ttacgcagcc tgtggtggtg gtggcgattg tgggcctcta tcgcacaggc aaatcctacc tgatgaacaa gctggctggg aagaaaaacg gcttctctct aggctccaca gtgaagtctc acaccaaggg aatctggatg tggtgtgtgc ctcatcccaa gaagccagaa cacaccctag ttctgctcga cactgagggc ctgggagata tagagaaggg tgacaatgag aatgactcct ggatctttgc cttggccatc ctcctgagca gcaccttcgt gtacaatagc atgggaacca tcaaccagca ggccatggac caacttcact atgtgacaga gctgacagat cgaatcaagg caaactcctc acctggtaac aattctgtag acgactcagc tgactttgtg agcttttttc cagcatttgt gtggactctc agagatttca ccctggaact ggaagtagat ggagaaccca tcactgctga tgactacttg gagctttcgc taaagctaag aaaaggtact gataagaaaa gtaaaagctt taatgatcct cggttgtgca tccgaaagtt cttccccaag aggaagtgct tcgtcttcga ttggcccgct cctaagaagt accttgctca cctagagcag ctaaaggagg aagagctgaa ccctgatttc atagaacaag ttgcagaatt ttgttcctac atcctcagcc attccaatgt caagactctt tcaggtggca ttccagtcaa tgggcctcgt ctagagagcc tggtgctgac ctacgtcaat gccatcagca gtggggatct accctgcagg gagaacgcag tcctggcctt ggcccagata gagaactcag ccgcagtgga aaaggctatt gcccactatg aacagcagat gggccagaag gtgcagctgc ccacggaaac cctccaggag ctgctggacc tgcacaggga cagtgagaga gaggccattg aagtcttcat gaagaactct ttcaaggatg tggaccaaat gttccagagg aaattagggg cccagttgga agcaaggcga gatgactttt gtaagcagaa ttccaaagca tcatcagatt gttgcatggc tttacttcag gatatatttg gccctttaga agaagatgtc aagcagggaa cattttctaa accaggaggt taccgtctct ttactcagaa gctgcaggag ctgaagaata agtactacca ggtgccaagg aaggggatac aggccaaaga ggtgctgaaa aaatatttgg agtccaagga ggatgtggct gatgcacttc tacagactga tcagtcactc tcagaaaagg aaaaagcgat tgaagtggaa cgtataaagg ctgaatctgc agaagctgca aagaaaatgt tggaggaaat acaaaagaag aatgaggaga tgatggaaca gaaagagaag agttatcagg aacatgtgaa acaattgact gagaagatgg agagggacag ggcccagtta atggcagagc aagagaagac cctcgctctt aaacttcagg aacaggaacg ccttctcaag gagggattcg agaatgagag caagagactt caaaaagaca tatgggatat ccagatgaga agcaaatcat tggagccaat atgtaacata ctctaa
Molecular Weight
67,209 Da
OMIM
600412
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GBP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GBP2. It may not necessarily be applicable to this product.

NCBI GI #
49119633
NCBI GeneID
2634
NCBI Accession #
BC073163
UniProt Secondary Accession #
Q6GPH0; Q6IAU2; Q86TB0
UniProt Related Accession #
P32456
NCBI Official Full Name
Homo sapiens guanylate binding protein 2, interferon-inducible, mRNA
NCBI Official Synonym Full Names
guanylate binding protein 2
NCBI Official Symbol
GBP2
UniProt Protein Name
Guanylate-binding protein 2
UniProt Synonym Protein Names
GTP-binding protein 2; GBP-2; HuGBP-2; Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2
Protein Family
Guanylate-binding protein
UniProt Gene Name
GBP2
UniProt Synonym Gene Names
GBP-2; HuGBP-2
UniProt Entry Name
GBP2_HUMAN
NCBI Protein Information
guanylate-binding protein 2

NCBI Summary for GBP2

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]
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UniProt Comments for GBP2

GBP2: a member of the family of large GTP-binding proteins (GBPs) that is inducible by interferon. Possesses a high GTP hydrolysis activity. GBPs are the most abundant cellular proteins expressed in response to interferon-gamma (IFN-gamma). IFN-gamma, tumor necrosis factor-alpha (TNF-alpha), and interleukin-1beta (IL-1beta) strongly induce the expression of GBP-1, -2, and -3.

Protein type: Hydrolase; Vesicle

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: immune response
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Research Articles on GBP2

1. Low GBP2 expression is associated with metastasis in breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GBP2 cdna clone

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram

Diseases associated with GBP2 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with GBP2 and Neoplasms
 Inflammation Antibodies  >5 publications with GBP2 and Inflammation
 Necrosis Antibodies  >3 publications with GBP2 and Necrosis
 Cardiovascular Diseases Antibodies  >2 publications with GBP2 and Cardiovascular Diseases
 Liver Diseases Antibodies  >2 publications with GBP2 and Liver Diseases
 Nervous System Diseases Antibodies  >2 publications with GBP2 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with GBP2 and Cell Transformation, Neoplastic
 Weight Gain Antibodies  >1 publications with GBP2 and Weight Gain
 Brain Diseases Antibodies  >1 publications with GBP2 and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with GBP2 and Kidney Diseases

Organs/Tissues associated with GBP2 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with GBP2 and Blood
 Liver Antibodies  >3 publications with GBP2 and Liver
 Lung Antibodies  >3 publications with GBP2 and Lung
 Ovary Antibodies  >2 publications with GBP2 and Ovary
 Lymph Node Antibodies  >2 publications with GBP2 and Lymph Node
 Connective Tissue Antibodies  >2 publications with GBP2 and Connective Tissue
 Vascular Antibodies  >2 publications with GBP2 and Vascular
 Muscle Antibodies  >1 publications with GBP2 and Muscle
 Kidney Antibodies  >1 publications with GBP2 and Kidney
 Bladder Antibodies  >1 publications with GBP2 and Bladder
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